PAINTDRINKER X CHEMICAL WARFARE X REBOUND

Have I told you, that I love you?

Separately, and not meant to detract from the main point of my post, how do you feel about the Cardarine cancer stuff?
I’m driving right now so voice to text might absolutely butcher this but I think it 100% does cause cancer and it’s mutagenic the human equivalent dose that caused rapid cancers in mice is about 45 mg and the rapid cancer onset was within 6 to 8 weeks, roughly Anytime we see an over expression of PR in nature or in humans it always leads to tumor growth and a higher cancer rate we’ve even seen this in human thyroid cell lines. Now the tests were done on mice that were predisposed to rapid cancers, but there’s many other tests, like they ran some tests on these field mice that had , no predisposition to cancer and genetically modified one set to have an over expression of PPA are, and guess what happened all of the genetically modified ones died rapidly of multiple cancers and the regular field mice lived their expected lives so this whole argument that like it’s not toxic and it’s not bad is retarded people just need to read more But I think short term exposure for lipid recovery is probably a little bit safer than running megadose GH long-term I would almost kind of compare it to something like cigarettes you’re not gonna get cancer if you smoke a couple cigarettes here and there or you smoke a cigarette you’re not just gonna get cancer from it it’s repeatedly doing it over and over again that’s eventually gonna lead to some sort of cell mutation so I think megadosing it for like one week to rapidly raise. Your HDL is probably safer than running 20 mg a day for three months straight. It’s actually probably much safer so at the end of the day it’s definitely toxic. It definitely causes cancer but it’s extremely good for your heart and your kidneys so there’s a trade-off I don’t know don’t run it often use it when it’s necessarily short term.
 
I’m driving right now so voice to text might absolutely butcher this but I think it 100% does cause cancer and it’s mutagenic the human equivalent dose that caused rapid cancers in mice is about 45 mg and the rapid cancer onset was within 6 to 8 weeks, roughly Anytime we see an over expression of PR in nature or in humans it always leads to tumor growth and a higher cancer rate we’ve even seen this in human thyroid cell lines. Now the tests were done on mice that were predisposed to rapid cancers, but there’s many other tests, like they ran some tests on these field mice that had , no predisposition to cancer and genetically modified one set to have an over expression of PPA are, and guess what happened all of the genetically modified ones died rapidly of multiple cancers and the regular field mice lived their expected lives so this whole argument that like it’s not toxic and it’s not bad is retarded people just need to read more But I think short term exposure for lipid recovery is probably a little bit safer than running megadose GH long-term I would almost kind of compare it to something like cigarettes you’re not gonna get cancer if you smoke a couple cigarettes here and there or you smoke a cigarette you’re not just gonna get cancer from it it’s repeatedly doing it over and over again that’s eventually gonna lead to some sort of cell mutation so I think megadosing it for like one week to rapidly raise. Your HDL is probably safer than running 20 mg a day for three months straight. It’s actually probably much safer so at the end of the day it’s definitely toxic. It definitely causes cancer but it’s extremely good for your heart and your kidneys so there’s a trade-off I don’t know don’t run it often use it when it’s necessarily short term.
Really appreciate your perspective!
 
Test/eq/primo/gh

Only pre and post slin. Lantus is great but I’m not trying to become dependent on it. Keeping gh lower at 6IU.

Might do an experiment and see if eq/primo has any effect on my e2. I’m doubtful
Kinda jealous if neither primo nor EQ impact your e2 lol. Would love to run boatloads of primo and lower test from an aesthetic perspective without feeling like crap.
 
Kinda jealous if neither primo nor EQ impact your e2 lol. Would love to run boatloads of primo and lower test from an aesthetic perspective without feeling like crap.
Not sure I've seen it on here in this summised fashion, but the following is something @Type-IIx posted in his Discord about E2 management r.e EQ and Mast.

"Boldenone (EQ) is an aromatizable androgen. Practically, while its use can (often) lead to sub-normal estradiol (E2)_, since it suppresses endogenous testosterone (T)/E2 and aromatizes at only a small fraction of the rate (Vmax) of T to estrone (E1) & E2. E1 is a weak estrogen, with only 2% E2's ER-α potency. The degree to which EQ aromatizes to E1 depends on 17β-HSD isozyme expression, under genetic control. Learn More in the Primo / Equipoise Crashed my E2 – Help!" article. So, while practically, using EQ can cause symptoms associated with low estrogens (e.g., joints aching, malaise), it is not a consequence of its inhibiting aromatase since it actually aromatizes!

Drostanolone (Masteron) is an aromatase inhibitor, and also prevents estrogen uptake into cells or tissue (e.g., synovial cells [joints], breast cells [antigynecomastic]) in a tissue-selective manner. Evidence of Masteron's aromatase inhibition can be found here: Authoritative evidence that AAS with saturated A-ring structures (e.g., Masteron, Primo, Anavar, Superdrol, Proviron) all inhibit aromatase"
 
Not sure I've seen it on here in this summised fashion, but the following is something @Type-IIx posted in his Discord about E2 management r.e EQ and Mast.

"Boldenone (EQ) is an aromatizable androgen. Practically, while its use can (often) lead to sub-normal estradiol (E2)_, since it suppresses endogenous testosterone (T)/E2 and aromatizes at only a small fraction of the rate (Vmax) of T to estrone (E1) & E2. E1 is a weak estrogen, with only 2% E2's ER-α potency. The degree to which EQ aromatizes to E1 depends on 17β-HSD isozyme expression, under genetic control. Learn More in the Primo / Equipoise Crashed my E2 – Help!" article. So, while practically, using EQ can cause symptoms associated with low estrogens (e.g., joints aching, malaise), it is not a consequence of its inhibiting aromatase since it actually aromatizes!

Drostanolone (Masteron) is an aromatase inhibitor, and also prevents estrogen uptake into cells or tissue (e.g., synovial cells [joints], breast cells [antigynecomastic]) in a tissue-selective manner. Evidence of Masteron's aromatase inhibition can be found here: Authoritative evidence that AAS with saturated A-ring structures (e.g., Masteron, Primo, Anavar, Superdrol, Proviron) all inhibit aromatase"
That’s a good summary of how EQ and mast both can reduce serum e2.

Anecdotally, primo murders my e2. 1.25g test and 600mg primo + 1000iu HCG EoD left me with e2 around 35. Perfect, but damn, powerful e2 management for me.

1.75g test + 1g mast + 1000iu HCG + 3x 25mg aromasin per week left me with e2 around 90.

I will be super curious to see the impact of EQ on my e2 + e1 when I get blood work done. My feels report says that it pretty powerfully lowers e2, and I’ve got no idea how it impacts my e1. Whatever it’s interplay between those two, I can say with almost certainty it results in a net estrogen lowering impact for me.

Currently running 1000iu HCG ED + 75iu HMG ED + 350mg test + 350mg mast + 1.2g EQ (just recently increased doses from where I was at), and zero AI.

Given how mast has historically had very little impact on my e2, I have to imagine that EQ is doing most of the heavy lifting in reducing my net estrogen burden since I’m not getting any typical elevated estrogen side effects. That leads me to believe I have lower 17β-HSD isozyme expression, too. I’m definitely getting the sides associated with lower estrogen balance but nothing too crazy.
 
Anecdotally, primo murders my e2. 1.25g test and 600mg primo + 1000iu HCG EoD left me with e2 around 35. Perfect, but damn, powerful e2 management for me.

Nuts. It did some stuff to me as well but not in that degree, 2/1 test/primo gave me a 45 e2 but without HCG, i'm taking DHEA though which raises estradiol but way lower than pure HCG.

Currently running 1000iu HCG ED + 75iu HMG ED + 350mg test + 350mg mast + 1.2g EQ (just recently increased doses from where I was at), and zero AI.

Given how mast has historically had very little impact on my e2, I have to imagine that EQ is doing most of the heavy lifting in reducing my net estrogen burden since I’m not getting any typical elevated estrogen side effects. That leads me to believe I have lower 17β-HSD isozyme expression, too. I’m definitely getting the sides associated with lower estrogen balance but nothing too crazy.

In about 2-3 hours i'll get my results to see where my e2 is with 500 test 300 EQ and 150 NPP and no AI, i was never able to pin point my "feels" regarding e2 but lately i'm feeling kinda off, fatigued and all joints hurt (despite the nandrolone). 5 weeks after 360 Test and 200 EQ my e2 was 25 (not ultrasensitive, which means actually lower value) and i have the impression that if i'd continue with the same dosages it would get even lower given the EQ halflife.

If EQ is THAT potent to reduce e2 i will never touch it again. Sometimes i feel fortunate not having to throw another med to control estrogen but man, that means i will never be able to push EQ or Primo above 500-600 without having a 1,2-1,5gr of test lol. I think the best case scenario is when you need to run them 1/1 to have a 40-50 estradiol.
 
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