MESO-Rx

Anabolic Steroids

PAINTDRINKER X CHEMICAL WARFARE X REBOUND

Trenbolonetax said:
Have I told you, that I love you?

Separately, and not meant to detract from the main point of my post, how do you feel about the Cardarine cancer stuff?
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I’m driving right now so voice to text might absolutely butcher this but I think it 100% does cause cancer and it’s mutagenic the human equivalent dose that caused rapid cancers in mice is about 45 mg and the rapid cancer onset was within 6 to 8 weeks, roughly Anytime we see an over expression of PR in nature or in humans it always leads to tumor growth and a higher cancer rate we’ve even seen this in human thyroid cell lines. Now the tests were done on mice that were predisposed to rapid cancers, but there’s many other tests, like they ran some tests on these field mice that had , no predisposition to cancer and genetically modified one set to have an over expression of PPA are, and guess what happened all of the genetically modified ones died rapidly of multiple cancers and the regular field mice lived their expected lives so this whole argument that like it’s not toxic and it’s not bad is retarded people just need to read more But I think short term exposure for lipid recovery is probably a little bit safer than running megadose GH long-term I would almost kind of compare it to something like cigarettes you’re not gonna get cancer if you smoke a couple cigarettes here and there or you smoke a cigarette you’re not just gonna get cancer from it it’s repeatedly doing it over and over again that’s eventually gonna lead to some sort of cell mutation so I think megadosing it for like one week to rapidly raise. Your HDL is probably safer than running 20 mg a day for three months straight. It’s actually probably much safer so at the end of the day it’s definitely toxic. It definitely causes cancer but it’s extremely good for your heart and your kidneys so there’s a trade-off I don’t know don’t run it often use it when it’s necessarily short term.
 
PaintDrinker said:
I’m driving right now so voice to text might absolutely butcher this but I think it 100% does cause cancer and it’s mutagenic the human equivalent dose that caused rapid cancers in mice is about 45 mg and the rapid cancer onset was within 6 to 8 weeks, roughly Anytime we see an over expression of PR in nature or in humans it always leads to tumor growth and a higher cancer rate we’ve even seen this in human thyroid cell lines. Now the tests were done on mice that were predisposed to rapid cancers, but there’s many other tests, like they ran some tests on these field mice that had , no predisposition to cancer and genetically modified one set to have an over expression of PPA are, and guess what happened all of the genetically modified ones died rapidly of multiple cancers and the regular field mice lived their expected lives so this whole argument that like it’s not toxic and it’s not bad is retarded people just need to read more But I think short term exposure for lipid recovery is probably a little bit safer than running megadose GH long-term I would almost kind of compare it to something like cigarettes you’re not gonna get cancer if you smoke a couple cigarettes here and there or you smoke a cigarette you’re not just gonna get cancer from it it’s repeatedly doing it over and over again that’s eventually gonna lead to some sort of cell mutation so I think megadosing it for like one week to rapidly raise. Your HDL is probably safer than running 20 mg a day for three months straight. It’s actually probably much safer so at the end of the day it’s definitely toxic. It definitely causes cancer but it’s extremely good for your heart and your kidneys so there’s a trade-off I don’t know don’t run it often use it when it’s necessarily short term.
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Really appreciate your perspective!
 
rexy said:
What's the stack plan now that lipids have recovered?
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Test/eq/primo/gh

Only pre and post slin. Lantus is great but I’m not trying to become dependent on it. Keeping gh lower at 6IU.

Might do an experiment and see if eq/primo has any effect on my e2. I’m doubtful
 
PaintDrinker said:
Test/eq/primo/gh

Only pre and post slin. Lantus is great but I’m not trying to become dependent on it. Keeping gh lower at 6IU.

Might do an experiment and see if eq/primo has any effect on my e2. I’m doubtful
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Kinda jealous if neither primo nor EQ impact your e2 lol. Would love to run boatloads of primo and lower test from an aesthetic perspective without feeling like crap.
 
Trenbolonetax said:
Kinda jealous if neither primo nor EQ impact your e2 lol. Would love to run boatloads of primo and lower test from an aesthetic perspective without feeling like crap.
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Not sure I've seen it on here in this summised fashion, but the following is something @Type-IIx posted in his Discord about E2 management r.e EQ and Mast.

"Boldenone (EQ) is an aromatizable androgen. Practically, while its use can (often) lead to sub-normal estradiol (E2)_, since it suppresses endogenous testosterone (T)/E2 and aromatizes at only a small fraction of the rate (Vmax) of T to estrone (E1) & E2. E1 is a weak estrogen, with only 2% E2's ER-α potency. The degree to which EQ aromatizes to E1 depends on 17β-HSD isozyme expression, under genetic control. Learn More in the Primo / Equipoise Crashed my E2 – Help!" article. So, while practically, using EQ can cause symptoms associated with low estrogens (e.g., joints aching, malaise), it is not a consequence of its inhibiting aromatase since it actually aromatizes!

Drostanolone (Masteron) is an aromatase inhibitor, and also prevents estrogen uptake into cells or tissue (e.g., synovial cells [joints], breast cells [antigynecomastic]) in a tissue-selective manner. Evidence of Masteron's aromatase inhibition can be found here: Authoritative evidence that AAS with saturated A-ring structures (e.g., Masteron, Primo, Anavar, Superdrol, Proviron) all inhibit aromatase"
 
rexy said:
Not sure I've seen it on here in this summised fashion, but the following is something @Type-IIx posted in his Discord about E2 management r.e EQ and Mast.

"Boldenone (EQ) is an aromatizable androgen. Practically, while its use can (often) lead to sub-normal estradiol (E2)_, since it suppresses endogenous testosterone (T)/E2 and aromatizes at only a small fraction of the rate (Vmax) of T to estrone (E1) & E2. E1 is a weak estrogen, with only 2% E2's ER-α potency. The degree to which EQ aromatizes to E1 depends on 17β-HSD isozyme expression, under genetic control. Learn More in the Primo / Equipoise Crashed my E2 – Help!" article. So, while practically, using EQ can cause symptoms associated with low estrogens (e.g., joints aching, malaise), it is not a consequence of its inhibiting aromatase since it actually aromatizes!

Drostanolone (Masteron) is an aromatase inhibitor, and also prevents estrogen uptake into cells or tissue (e.g., synovial cells [joints], breast cells [antigynecomastic]) in a tissue-selective manner. Evidence of Masteron's aromatase inhibition can be found here: Authoritative evidence that AAS with saturated A-ring structures (e.g., Masteron, Primo, Anavar, Superdrol, Proviron) all inhibit aromatase"
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That’s a good summary of how EQ and mast both can reduce serum e2.

Anecdotally, primo murders my e2. 1.25g test and 600mg primo + 1000iu HCG EoD left me with e2 around 35. Perfect, but damn, powerful e2 management for me.

1.75g test + 1g mast + 1000iu HCG + 3x 25mg aromasin per week left me with e2 around 90.

I will be super curious to see the impact of EQ on my e2 + e1 when I get blood work done. My feels report says that it pretty powerfully lowers e2, and I’ve got no idea how it impacts my e1. Whatever it’s interplay between those two, I can say with almost certainty it results in a net estrogen lowering impact for me.

Currently running 1000iu HCG ED + 75iu HMG ED + 350mg test + 350mg mast + 1.2g EQ (just recently increased doses from where I was at), and zero AI.

Given how mast has historically had very little impact on my e2, I have to imagine that EQ is doing most of the heavy lifting in reducing my net estrogen burden since I’m not getting any typical elevated estrogen side effects. That leads me to believe I have lower 17β-HSD isozyme expression, too. I’m definitely getting the sides associated with lower estrogen balance but nothing too crazy.
 
Trenbolonetax said:
Anecdotally, primo murders my e2. 1.25g test and 600mg primo + 1000iu HCG EoD left me with e2 around 35. Perfect, but damn, powerful e2 management for me.
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Nuts. It did some stuff to me as well but not in that degree, 2/1 test/primo gave me a 45 e2 but without HCG, i'm taking DHEA though which raises estradiol but way lower than pure HCG.

Trenbolonetax said:
Currently running 1000iu HCG ED + 75iu HMG ED + 350mg test + 350mg mast + 1.2g EQ (just recently increased doses from where I was at), and zero AI.

Given how mast has historically had very little impact on my e2, I have to imagine that EQ is doing most of the heavy lifting in reducing my net estrogen burden since I’m not getting any typical elevated estrogen side effects. That leads me to believe I have lower 17β-HSD isozyme expression, too. I’m definitely getting the sides associated with lower estrogen balance but nothing too crazy.
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In about 2-3 hours i'll get my results to see where my e2 is with 500 test 300 EQ and 150 NPP and no AI, i was never able to pin point my "feels" regarding e2 but lately i'm feeling kinda off, fatigued and all joints hurt (despite the nandrolone). 5 weeks after 360 Test and 200 EQ my e2 was 25 (not ultrasensitive, which means actually lower value) and i have the impression that if i'd continue with the same dosages it would get even lower given the EQ halflife.

If EQ is THAT potent to reduce e2 i will never touch it again. Sometimes i feel fortunate not having to throw another med to control estrogen but man, that means i will never be able to push EQ or Primo above 500-600 without having a 1,2-1,5gr of test lol. I think the best case scenario is when you need to run them 1/1 to have a 40-50 estradiol.
 
Eddie. said:
Nuts. It did some stuff to me as well but not in that degree, 2/1 test/primo gave me a 45 e2 but without HCG, i'm taking DHEA though which raises estradiol but way lower than pure HCG.
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Yeah, I really wish it wasn't that good at lowering my E2 lol. I wondered in the past why 250 test and 200 primo didn't make me feel good...got my answer (probably) after doing bloods on the much higher doses. My e2 was probably wrecked.

Eddie. said:
In about 2-3 hours i'll get my results to see where my e2 is with 500 test 300 EQ and 150 NPP and no AI, i was never able to pin point my "feels" regarding e2 but lately i'm feeling kinda off, fatigued and all joints hurt (despite the nandrolone). 5 weeks after 360 Test and 200 EQ my e2 was 25 (not ultrasensitive, which means actually lower value) and i have the impression that if i'd continue with the same dosages it would get even lower given the EQ halflife.

If EQ is THAT potent to reduce e2 i will never touch it again. Sometimes i feel fortunate not having to throw another med to control estrogen but man, that means i will never be able to push EQ or Primo above 500-600 without having a 1,2-1,5gr of test lol. I think the best case scenario is when you need to run them 1/1 to have a 40-50 estradiol.
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Please update me with where your e2 is at those doses of test + EQ. Did you happen to get E1 tested?

I love EQ so far, but what I also really hate, is the fact it's such a long ester and it really does take quite a bit of time to reach "steady state" as far as E2 goes.

I'm with you; I wish I could run 1:1 test / primo and have higher e2. I'm cautiously optimistic that EQ isn't as potent at lowering net estrogen burden compared to primo for me, but we shall see with a bit of time.

I guess the case could be made that we both ought to be able to throw in Trestolone in low doses alongside primo / EQ with zero AI...maybe that has been our true calling all along!
 
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DugPrime said:
Have you ever tried dbol? For me, 50mg was much stronger than 100mg of anadrol in every aspect, but I don’t know how the dosages compare.
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Yeah I've tried dbol. Never actually ran a true cycle of it. Just have pulsed it randomly when I wanted a sick pump + feel good lift. I get a nice little mood boost from it.

For me, anadrol and dbol were somewhat similar in their antigravity effect when "pulsed" randomly on a day I wanted to PR. Though I think on a mg:mg basis dbol is stronger.

Sorry, @PaintDrinker for clogging up your log...tell me / us to beat it, please, if it's bothering you.
 
Trenbolonetax said:
Yeah I've tried dbol. Never actually ran a true cycle of it. Just have pulsed it randomly when I wanted a sick pump + feel good lift. I get a nice little mood boost from it.

For me, anadrol and dbol were somewhat similar in their antigravity effect when "pulsed" randomly on a day I wanted to PR. Though I think on a mg:mg basis dbol is stronger.

Sorry, @PaintDrinker for clogging up your log...tell me / us to beat it, please, if it's bothering you.
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No brother I actually enjoy reading through these comments I’m an absolute faggot that spends all his time talking to this one lady now so I apologize for that. I have 0 free time between work and this new obsession. I’m going to respond to everything on here later today. I do enjoy everyone’s insight especially on compounds and always big props to @rexy for dropping facts love it.

Still didn’t get a new phone after my telegram ban. No more edgy jokes allowed that AI is stupid. Need a new burner anyways.

Quick mention, I’ve never seen any e2 reduction from any steroid I still need ai. I was actually going to keep test maybe around 400-500 and push primo and eq up until e2 moves. I pull labs once a month so I’ll be monitoring it closely.

How about my 52 hdl! It hasn’t been this high since I started blasting almost 3 years ago. I think the 5amino and inject sr has a lot to do with it, I’m going to toy around with a longterm protocol but lower doses
 
PaintDrinker said:
My body wants to be trans so fucking bad I’m basically fucked dude.
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Interested Peeping Tom GIF
 
PaintDrinker said:
No brother I actually enjoy reading through these comments I’m an absolute faggot that spends all his time talking to this one lady now so I apologize for that. I have 0 free time between work and this new obsession. I’m going to respond to everything on here later today. I do enjoy everyone’s insight especially on compounds and always big props to @rexy for dropping facts love it.

Still didn’t get a new phone after my telegram ban. No more edgy jokes allowed that AI is stupid. Need a new burner anyways.

Quick mention, I’ve never seen any e2 reduction from any steroid I still need ai. I was actually going to keep test maybe around 400-500 and push primo and eq up until e2 moves. I pull labs once a month so I’ll be monitoring it closely.

How about my 52 hdl! It hasn’t been this high since I started blasting almost 3 years ago. I think the 5amino and inject sr has a lot to do with it, I’m going to toy around with a longterm protocol but lower doses
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hahaha sounds like you're in love, bro!

I'm not super familiar with telegram but this is a good PSA for me not to say stupid stuff on that thing.

Kinda jealous about you being able to push primo and EQ up with lower test...and also curious about your experiment with them.

Your 52 HDL is wild, man. I think you're right about the SR9009 and 5Amino also playing a big role. Curious how my lipids are holding up on the 5Amino...I need to get bloods soon but I keep fucking around with doses. Been a minute since I've run SR; I last got it from Modern Aminos. Suggestions for places to acquire?
 
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