MESO-Rx Sponsor Pharmacom Labs officials and our Basicstero.com store

[-Maui-]

That's one conclusion. Any other ones? Purpose of needlessly using EO in the products? Oil preservative? Let's get real.

EO can be dangerous for mitochondria at the site of synthesis during ethanol metabolism. The hydrolyzed eo enters the bloodstream. The study modeled an increase in concentration in the myocardium, for this it was necessary to inject EO directly into the heart, which is logical.

 

[RThoads]

Discussions, concerns, and suggestions regarding ways to improve the products are positive and valuable. None of us, no matter what one's background or experiences, know everything and there is always room for each of us to learn more. This is one of the most powerful benefits to our networking online, such as being part of the community here.
I appreciate positions, arguments, experiences, and, most of all, references on either side of a discussion or debate because I can learn something from everyone.

If there are recurring common concerns about something or many people have similar suggestions, that means it important enough for me to ask the source to take into consideration. Regardless of what is decided by discussions or debates here, it is part of my job, and good for the business, for me to facilitate communication and try the best within my power and ability to use the insight to foster positive outcomes for everyone involved.

We all want the same things such as access to good safe products and the freedom to make our own choices without the agenda of governments, and other institutions, interfering or limiting our freedom.
If we all keep these things in mind, we realize that we're all on the same team here just trying to learn, be healthy, and be free.

 

[pipo]

You did?

MESO-Rx Sponsor Post in thread 'Pharmacom Labs officials and our Basicstero.com store'

Nov 28, 2024

Myocardial Cell Damage by Fatty Acid Ethyl Esters : Journal of Cardiovascular Pharmacology

e (FAEE) to mitochondria and their capacity to hydrolyze these FAEE. In vivo effects of ethyl esters were studied by the direct transfer of [3H]oleate into the myocardium. Mitochondria were prepared from the myocardium of injected rats, and the amount of [3H]oleate bound to them was determined...

journals.lww.com

https://onlinelibrary.wiley.com/doi/10.1080/13556219872308

• readalot

• 

Still nothing. We don’t inject pure eo in heart. If you find something that studies how it act when is injected IM I'm all ears.

 

[readalot]

Still nothing. We don’t inject pure eo in heart. If you find something that studies how it act when is injected IM I'm all ears.

So I take it you didn't read second paper? Won't look even when it is put under your nose? Ok.

 

[pipo]

That's one conclusion. Any other ones? Purpose of needlessly using EO in the products? Oil preservative? Let's get real.

Smoother injection is one reason. Is a difference in how it feels a injection with some eo in it or no eo. For them is that the oils don't crash when shipped in the winter

In the past I used pharmacom for many years until I start brew my oils.
I have brew and use all kind of oils(gso,mct,peanuts, sesame, castor,peach) and was a difference between those and what pharmacom would feels at site injection.
Then I start to use their recipe and add 10-15% EO in gso oil and it was better. That's why I usually use eo in my brews as I don't see any evidence why I wouldn't.

I don't promote to use eo but if anyone is so against it and it's seen like the devil point some evidence.

 

[readalot]

Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase - PMC

The recent identification of myocardial metabolites of ethanol--fatty acid ethyl esters--suggests that some of the pathophysiological derangements associated with alcohol-induced heart muscle disease may be a consequence of products of myocardial ...

pmc.ncbi.nlm.nih.gov

 

[readalot]

Metabolism background:

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism - PMC

Fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of ethanol that accumulate in human tissues upon ethanol intake. Although FAEEs are considered as toxic metabolites causing cellular dysfunction and tissue damage, the enzymology of FAEE ...

pmc.ncbi.nlm.nih.gov

 

[readalot]

For them is that the oils don't crash when shipped when it's cold

Bingo! Well done.

 

[RThoads]

@readalot I'm just quoting these so I may find them in my post history again at a later date. Thank you for sharing information.

Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase - PMC

The recent identification of myocardial metabolites of ethanol--fatty acid ethyl esters--suggests that some of the pathophysiological derangements associated with alcohol-induced heart muscle disease may be a consequence of products of myocardial ...

pmc.ncbi.nlm.nih.gov

Metabolism background:

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism - PMC

Fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of ethanol that accumulate in human tissues upon ethanol intake. Although FAEEs are considered as toxic metabolites causing cellular dysfunction and tissue damage, the enzymology of FAEE ...

pmc.ncbi.nlm.nih.gov

 

[pipo]

So I take it you didn't read second paper? Won't look even when it is put under your nose? Ok.

Poison is in the dosage. It's like you compare apples to oranges

 

[readalot]

Poison is in the dosage.

Absolutely.

It's like you compare apples to oranges

???

Reader can decide whether claim by Pharmacom that EO is innocuous is correct.

 

[readalot]

Fatty Acid Ethyl Esters

Despite the fact that alcoholism is a major cause of disease in society, little is known about the mechanism by which ethanol abuse induces organ damage. One increasingly compelling hypothesis is that fatty acid ethyl esters (FAEEs), esterified products of fatty...

link.springer.com

 

[readalot]

Fatty Acid Ethyl Ethers: New Modulators of Acute Ethanol-Mediated Hepatotoxicity? - PMC

pmc.ncbi.nlm.nih.gov

 

[readalot]

Fatty acid ethyl esters: current facts and speculations - PubMed

Increasing evidence indicates that fatty acid ethyl esters (FAEE) play a role in ethanol-induced organ damage and may serve as long-term markers of ethanol intake. This report summarizes the current knowledge on the toxicity of FAEE, the enzymes associated with FAEE synthesis, FAEE as fatty acid...

pubmed.ncbi.nlm.nih.gov