Please help with injectable Dianabol.

[Khapp1]

I’m prepping for a Lean-Bulk cycle and was able to get some injectable D-bol from a reliable source. I couldn’t find much information on it here and online. I have tried the regular oral d-bol in the past with great success. My questions are as follows:
1. Does injectable have the same harsh effects on the liver or does it bypass this completely because it’s not being broken down in the stomach? Can I run this compound longer because it’s injectable?
2. What is the onset time with the injectable version?
3. What is the proper dosage for this? The vial I have is 50 mg/ 1 ml. Should I follow the same protocol as I normally do with the oral version? (Which is start with 25 mg and titrate up in the following weeks).
I’m new here so please forgive me if I missed anything and thank you for any advice or knowledge that you can provide.

 

[Spaceman Spiff]

To answer question 1.

Injectable drugs still has harsh effects on the liver. Your liver and kidneys still need to clear out drugs. Even intravenous drugs need to be cleared by organs.

 

[Mongo966]

1. It will still affect your liver but potentially not as much as oral because it skips the first pass.
2. 1 or 2 hours preworkout is fine.
3. Start at 25mg. If it's good dbol you'll likely need less of it than your oral dose.

Based on my limited personal experience with it. Take it for what it's worth.

 

[Khapp1]

Thank you !

 

[BigTomJ]

1. Does injectable have the same harsh effects on the liver or does it bypass this completely because it’s not being broken down in the stomach? Can I run this compound longer because it’s injecta

No.
There's pretty much zero reason to run injectable orals IMO.
Very little reason to run any orals for that matter for a non contest setting imo.

 

[AlexDavis43]

There's pretty much zero reason to run injectable orals IMO.

Whenever I read "Skips first pass liver metabolism,"
I think
"whoopty doo, but still experiences 2-99 passes until it's completely eliminated"

Injecting saved you <1% of a small number over oral intake.

So no difference unless you prefer orals over injecting for other reasons. Some people don't like injecting.

 

[Jin23]

I’m prepping for a Lean-Bulk cycle and was able to get some injectable D-bol from a reliable source. I couldn’t find much information on it here and online. I have tried the regular oral d-bol in the past with great success. My questions are as follows:
1. Does injectable have the same harsh effects on the liver or does it bypass this completely because it’s not being broken down in the stomach? Can I run this compound longer because it’s injectable?
2. What is the onset time with the injectable version?
3. What is the proper dosage for this? The vial I have is 50 mg/ 1 ml. Should I follow the same protocol as I normally do with the oral version? (Which is start with 25 mg and titrate up in the following weeks).
I’m new here so please forgive me if I missed anything and thank you for any advice or knowledge that you can provide.

Injectable orals do not present with the same pharmacokinetic profile. Tmax should be longer and thus the drug will have limited pre workout utility. This is due to the slower release of the drug from the oil depot into the bloodstream. I'm not aware of any official studies which have measured dbol's (suspended in oil) kinetics, thus everything is purely speculative from my part ...

The benefits of injectable oral steroids are certainly the avoidance of Gi disturbances. And for this purpose alone, depending on how susceptible one's gi is to sides, it makes a lot of sense to inject orals. Alterations to stomach HCL secretion, bile flow, microbiome alterations, etc, should be fairly common.

Regarding liver health, the biggest issue with oral ingestion is the concentration of the drug, to which the liver is exposed. Both routes will pass the liver, but when ingested, the liver enzymes have a higher chance of being saturated in comparison to the more slow and gradual release from the muscle depot.

Injecting a steroid delivers the compound directly to the blood stream and tissue's, where it actively binds to plasma proteins and the free portion of the steroid binds to AR's in muscle and organ tissue. The biggest difference in the routes of administration is going to be the active metabolites. Most all oral aas are in effect pro-drugs, and their metabolites can be stronger or simply have a profoundly different effect. When the drug is taken orally it will reach your target tissues only via: the portal vein - liver - blood stream and in this process the drug is heavily modified. Due to this it is hard to distinguish between how much mg's of one steroid you should inject, compared to per-os. Granted, when injecting dbol the bioavailability is greater, so more mg's will enter your blood stream (the difference can be substantial 30 - 50%), but if the active metabolites of the first liver pass are stronger then the parent compound (which is the only active compound when injected), you might need the same amount of the steroid when injecting to see similar results. And ofc taking in to account different androgenicity of parent compound vs active metabolites, subjectively judging the drugs effect might be a hard and fraudulent endavour (because you are in effect comparing two different drugs).

50mg's of orally ingested dbol is a high dose. 30 is plenty for most. I've personally never injected dbol so can't comment really, but I'd start somewhere around with 15 mg's when injecting.

 

[Khapp1]

Thanks for all the great input!

 

[Khapp1]

Injectable orals do not present with the same pharmacokinetic profile. Tmax should be longer and thus the drug will have limited pre workout utility. This is due to the slower release of the drug from the oil depot into the bloodstream. I'm not aware of any official studies which have measured dbol's (suspended in oil) kinetics, thus everything is purely speculative from my part ...

The benefits of injectable oral steroids are certainly the avoidance of Gi disturbances. And for this purpose alone, depending on how susceptible one's gi is to sides, it makes a lot of sense to inject orals. Alterations to stomach HCL secretion, bile flow, microbiome alterations, etc, should be fairly common.

Regarding liver health, the biggest issue with oral ingestion is the concentration of the drug, to which the liver is exposed. Both routes will pass the liver, but when ingested, the liver enzymes have a higher chance of being saturated in comparison to the more slow and gradual release from the muscle depot.

Injecting a steroid delivers the compound directly to the blood stream and tissue's, where it actively binds to plasma proteins and the free portion of the steroid binds to AR's in muscle and organ tissue. The biggest difference in the routes of administration is going to be the active metabolites. Most all oral aas are in effect pro-drugs, and their metabolites can be stronger or simply have a profoundly different effect. When the drug is taken orally it will reach your target tissues only via: the portal vein - liver - blood stream and in this process the drug is heavily modified. Due to this it is hard to distinguish between how much mg's of one steroid you should inject, compared to per-os. Granted, when injecting dbol the bioavailability is greater, so more mg's will enter your blood stream (the difference can be substantial 30 - 50%), but if the active metabolites of the first liver pass are stronger then the parent compound (which is the only active compound when injected), you might need the same amount of the steroid when injecting to see similar results. And ofc taking in to account different androgenicity of parent compound vs active metabolites, subjectively judging the drugs effect might be a hard and fraudulent endavour (because you are in effect comparing two different drugs).

50mg's of orally ingested dbol is a high dose. 30 is plenty for most. I've personally never injected dbol so can't comment really, but I'd start somewhere around with 15 mg's when injecting.

Thanks for the key input. You definitely know your compounds. I appreciate it.

 

[Bigbicep]

Does injectable dbol have the same effect as when taken orally ? As in gains wise ?

 

[caffaddicted]

why people still using dianabol?