TRT@40
Well-known Member
Being on prescription TRT for about 2 years now and a current cycle of prime (650mg/wk), test(400mg/wk), Anavar(25-50mg/wk), Deca (200mg/wk), about 2iu of pharma grade HGH, my sperm dropped to 2million from over 24million when I was not on TRT or cycle. My fertility doc is suggesting me to run 2500IU (yes, 2500) twice day for 2 months for restarting HPTA. He is a fertility/IVF doc who I think does not know enough in the area of TRT. I told him I want to kick start endogenous test production as this way ensures the best quality of sperm so he suggested that dose of HCG. My lady wants a 2nd baby and therefore, my quest for info on the subject.
Actually, my very first TRT protocol was HCG monotherapy with 1000IU EOD, test levels came up to about 700 from 200 at baseline but because the endo did not prescribe me an AI, e2 was really high. So, I know that on 5000IU of HCG per day, estrogen is going to really high.
For my current situation, fertility is the top priority and next one down is keeping the gains.
Now, I am kind of stuck between 2 options:
(1) stop TRT and the cycle completely to follow up with full PCT then go back to TRT/Cycling after a pregnancy. My natty test levels were low at 200 pre TRT which could be due to not doing PCT at the end of my last cycle about 14 years ago. Is there any chance that after following a proper PCT, my endogenous test production will be better than pre TRT levels of 200.
(2) stop the cycle and go back to TRT prescription of 200mg/wk test with 500iu HCG eod until pregnancy. There are some studies showing that this option might be the best compromise for maintaining fertility and staying on TRT prescription.
Study by Coviello, A.D., et al., tittled “Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression” demonstrated in men with normal reproductive physiology receiving 200mg/wk of test e and 500iu eod of HCG showed an increase in intra-testicular testosterone which I think may help with spermatogenesis.
Another study confirmed in TRT patients, intra-testicular testosterone can be maintained by combining 500iu of HCG eod along with Test. By adding HCG to Test for TRT therapy, there is no impact on the sperm parameters. Hsieh, T.C., et al., Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy. J Urol, 2013. 189(2): p. 647-50.
Either option needs to be followed at least 3 months before trying for a baby as it takes about 3 months for the sperm to mature.
Which option you fellas with knowledge on the subject think is the best choice for fertility? Any suggestions/advice will be greatly appreciated.
Cheers....
Note: I am on week 9 of the cycle. I have already stopped anavar as I had been on it for 8weeks. Test C has been tapered down to 200mg/wk since I started taking 1000iu eod which is going to increase test (and estrogen). I will increase HGH (generic) to 4iu/day once I cut the cycle.
Actually, my very first TRT protocol was HCG monotherapy with 1000IU EOD, test levels came up to about 700 from 200 at baseline but because the endo did not prescribe me an AI, e2 was really high. So, I know that on 5000IU of HCG per day, estrogen is going to really high.
For my current situation, fertility is the top priority and next one down is keeping the gains.
Now, I am kind of stuck between 2 options:
(1) stop TRT and the cycle completely to follow up with full PCT then go back to TRT/Cycling after a pregnancy. My natty test levels were low at 200 pre TRT which could be due to not doing PCT at the end of my last cycle about 14 years ago. Is there any chance that after following a proper PCT, my endogenous test production will be better than pre TRT levels of 200.
(2) stop the cycle and go back to TRT prescription of 200mg/wk test with 500iu HCG eod until pregnancy. There are some studies showing that this option might be the best compromise for maintaining fertility and staying on TRT prescription.
Study by Coviello, A.D., et al., tittled “Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression” demonstrated in men with normal reproductive physiology receiving 200mg/wk of test e and 500iu eod of HCG showed an increase in intra-testicular testosterone which I think may help with spermatogenesis.
Another study confirmed in TRT patients, intra-testicular testosterone can be maintained by combining 500iu of HCG eod along with Test. By adding HCG to Test for TRT therapy, there is no impact on the sperm parameters. Hsieh, T.C., et al., Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy. J Urol, 2013. 189(2): p. 647-50.
Either option needs to be followed at least 3 months before trying for a baby as it takes about 3 months for the sperm to mature.
Which option you fellas with knowledge on the subject think is the best choice for fertility? Any suggestions/advice will be greatly appreciated.
Cheers....
Note: I am on week 9 of the cycle. I have already stopped anavar as I had been on it for 8weeks. Test C has been tapered down to 200mg/wk since I started taking 1000iu eod which is going to increase test (and estrogen). I will increase HGH (generic) to 4iu/day once I cut the cycle.
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just my opinion
