Ghoul
Well-known Member
And in case anyone decides to follow up with more research, I'm aware high levels of retinoic acid (RA) are associated with depression and or personality changes sometimes experienced by people using standard/high levels of accutane, as well as with age related cognitive decline.
HOWEVER, these conditions are also associated with slower brain metabolism in the presence of high RA.
Low levels of Retinoic Acid, with normal brain metabolism, are associated with, to put it simply, being stupid, technically "low levels of cognition, learning, memory.".
I don't think it's retinoic acid causing the slower brain metabolism, but when it's slowed by some other factor, an unutilized surplus of RA builds up.
When RA is deficient, due to poor diet or some other factor, and brain metabolism is normal, cognition doesn't develop well and declines.
So possibly, with modafinil induced accelerated brain metabolism, a surplus supply of RA is put to use, building out the brain's capacity.
HOWEVER, these conditions are also associated with slower brain metabolism in the presence of high RA.
Low levels of Retinoic Acid, with normal brain metabolism, are associated with, to put it simply, being stupid, technically "low levels of cognition, learning, memory.".
I don't think it's retinoic acid causing the slower brain metabolism, but when it's slowed by some other factor, an unutilized surplus of RA builds up.
When RA is deficient, due to poor diet or some other factor, and brain metabolism is normal, cognition doesn't develop well and declines.
So possibly, with modafinil induced accelerated brain metabolism, a surplus supply of RA is put to use, building out the brain's capacity.