primo and test lab work thread - e2 crushed from primo

[buzzingonaas]

Wver



Ever get a test while taking Tamoxifen? I had read it can actually be beneficial for lipid profile and found It works wonders on my lipid panel somehow, especially HDL. I’ve just never felt it was safe to run long term. But I think Im about to add a low dose to my last 4 weeks of this cycle to boost hdl.

I’ve heard that too, that’s interesting. Maybe adding in tamoxifen during a 20 week blast and then removing during an extended cruise period could be beneficial

And no I’ve never taken bloods while using tamoxifen, my experience with it is very very limited as my estrogen is usually controlled well by mast or primo

 

[Ouch]

I’ve heard that too, that’s interesting. Maybe adding in tamoxifen during a 20 week blast and then removing during an extended cruise period could be beneficial

And no I’ve never taken bloods while using tamoxifen, my experience with it is very very limited as my estrogen is usually controlled well by mast or primo

I’ve tested twice while on it. Once during a cycle of test/deca and one time natty trying a gyno protocol. Both times my lipids were way better than baseline. This was before starting a statin. My only hesitation now is with running primo which is already an oddball for e2 sides for me. But it’s only 4 weeks so gonna try it and probably run it through pct

 

[buzzingonaas]

I’ve tested twice while on it. Once during a cycle of test/deca and one time natty trying a gyno protocol. Both times my lipids were way better than baseline. This was before starting a statin. My only hesitation now is with running primo which is already an oddball for e2 sides for me. But it’s only 4 weeks so gonna try it and probably run it through pct

That’s interesting. My only hesitation to do so is just that I wouldn’t really need a serm unless I’m running dbol or deca or something? And then it comes down to which is potentially more harmful/side effects: ezetimibe, statins, or tamoxifen (probably statins then tamoxifen, then ezetimibe)

 

[egruberman]

then it comes down to which is potentially more harmful/side effects: ezetimibe, statins, or tamoxifen (probably statins then tamoxifen, then ezetimibe)

IMHO, the frequency of statin side effects is overstated. Especially if the doses are kept low.

That sounds interesting. Was it like a 23 and me type test or something more specialized?

The test was from Color. It was free. I can't see that I found it to be especially useful. Interesting, but not entirely useful.

Have you experienced that fast metabolism of caffeine in reality?

Yes. I can consume endless amounts of caffeine without getting jittery. It also doesn't impact my sleep, though I don't try to poke the bear in that regard because my sleep is bad enough as it is, so I cut off the caffeine at 2PM.

By relatively low are we talking like less than 50-60gs of added fats?

That seems about right. I used to eat a fair bit of butter, cream, and cook with ghee. My lipids weren't terrible when I was doing that, but I've backed way off on the saturated fats.

Now, I cook with avocado oil and mostly focus on leaner cuts. Added fat might be some olive oil or some nuts. I still occasionally consume fatty things, but it's not a component of my daily diet.

 

[Ouch]

If you have FH, I'm curious what your CAC score shows. Might as well get started with Repatha. Probably hard to get insurance to cover, but the copay card is easy to get.

IMHO, PCSK9 inhibitors are the best thing since statins.

Just reporting back as promised. My CAC score is 11. Which puts me in the 75th percentile for my age. All of the calcium score comes from the widow maker artery however.

 

[egruberman]

My CAC score is 11.

That’s low enough that it could be in the margin of error…. Though it’s likely there is *some* calcified plaque which also implies the presence of soft plaques.

A cardiologist probably wouldn’t treat it as a big deal, encouraging you to get on a statin. The threshold seems to be ~6% Framingham 10yr risk score.

If it were me and I’m in a similar situation with a 40-something CAC, not bad but not great, I’d try all the various interventions I could get my hands on and see what I can tolerate sustainably.

For me that’s all the things. Getting ready for a blast so I had a blood draw today to check my lipids among other things. Been on Repatha for 6 months. Curious to see how low my numbers will be in the presence of gear.

The development in plaque correlates with “time under the curve” for LDL and ApoB exposure. My working premise is that the lower I keep my lipids the more cycles I can run reasonably safely as I get old.

Ideally, I’ve had a bit of a reversal. I should repeat the CAC soon to see. Looking forward to that heart health thread.