Add this to the 673452648792 other things hypothesized to cause Alzheimer's.Hopefully for you it'll be something worse.
I'll be sure to send a get well card signed "Bubble Boy", lol.
The endotoxin hypothesis of Alzheimer’s disease - Molecular Neurodegeneration
Lipopolysaccharide (LPS) constitutes much of the surface of Gram-negative bacteria, and if LPS enters the human body or brain can induce inflammation and act as an endotoxin. We outline the hypothesis here that LPS may contribute to the pathophysiology of Alzheimer’s disease (AD) via peripheral...molecularneurodegeneration.biomedcentral.com
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MESO-Rx
Anabolic Steroids
Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic
- Thread starter Qingdao Sigma Chemicals
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egruberman
Well-known Member
This is not the sentence that comes out of an intelligent, mature, well-adjusted human being. If your arguments fail to be compelling to your audience, it could be that your audience lacks the capacity to understand them, but Occam's razor suggests otherwise.
AlexDavis43
Member
Or sent it in for the comprehensive Readalot heavy metal and sterility testing that he's demanding of others. Which he would never do.
Or saving a few bucks on that because the benefits (fat loss) far outweigh the risks (because he's very fat).
Roidzilla
Banned
Nothing more 2 say about this guy. On my ignorelist since months.
Ghoul
Well-known Member
Yes ofc. And if it turns out a simple heating process by the end user can ensure the sterility of UGL gear, is that a bad thing?
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Ghoul
Well-known Member
I've never demanded anyone do anything, you're lying in an attempt to get others to share your irrational anger over this topic.
MESO is a place where ideas are discussed and debated, where knowledge is shared and ideas are explored.
One can talk about the possibility of improving things by looking at best practices, in this case pharma, the underlying reasons those practices are used, and what can be reasonably employed from those in the way we do things.
It's how HARM REDUCTION moves forward.
You have to keep bringing up the heavy metal straw man argument, because the only response to my posts about ensuring sterility is "I haven't had to go to the hospital with an infection", which most who brew their gear like this can say too....
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Ghoul
Well-known Member
For my small but vocal clique of haters, don't worry, I haven't forgotten how much you love my advocacy of GLPs as the revolutionary health improvers they are. Let me take a moment pin your ass with this 16g harpoon:
-------------------------
Yale University professor Dr Harlan Krumholz, editor-in-chief of the Journals of the American College of Cardiology said:
These “remarkable” drugs are poised to revolutionize heart care and could even slow biological aging, allowing people to "live longer and better" lives."
The US expert added: "This is an anti-obesity medication but honestly you could just think about it as a health promotion medication, or in the case of these studies, heart medication.
"It’s a multi-purpose drug. The evidence does excite me. It’s an important inflection point in medicine to have a tool like this that can so promote health."
www.express.co.uk
And ironically;
"A leading theory is that the jabs reduce inflammation. Inflammation is a normal part of the body’s immune response to injury or infection but is believed to increase risk of many conditions, from arthritis and dementia to cancer and bowel disease."
Guess what gear with excess bacteria and endotoxin cause over time? Even in the absence of acute illness? Systemic inflammation.
So yeah @alan43 , the unending pain in those "achy knees" you'll likely experience for decades might be avoided by reducing inflammation and the things that contribute to it, like imperfectly sterilized gear injected a few times a week.
-------------------------
Yale University professor Dr Harlan Krumholz, editor-in-chief of the Journals of the American College of Cardiology said:
These “remarkable” drugs are poised to revolutionize heart care and could even slow biological aging, allowing people to "live longer and better" lives."
The US expert added: "This is an anti-obesity medication but honestly you could just think about it as a health promotion medication, or in the case of these studies, heart medication.
"It’s a multi-purpose drug. The evidence does excite me. It’s an important inflection point in medicine to have a tool like this that can so promote health."
'Remarkable' new drugs are set to slow ageing and unlock 'Fountain of Youth'
A raft of studies unveiled at the world's largest cardiology conference triggered fresh excitement about the potential health benefits of weight loss drugs.
And ironically;
"A leading theory is that the jabs reduce inflammation. Inflammation is a normal part of the body’s immune response to injury or infection but is believed to increase risk of many conditions, from arthritis and dementia to cancer and bowel disease."
Guess what gear with excess bacteria and endotoxin cause over time? Even in the absence of acute illness? Systemic inflammation.
So yeah @alan43 , the unending pain in those "achy knees" you'll likely experience for decades might be avoided by reducing inflammation and the things that contribute to it, like imperfectly sterilized gear injected a few times a week.
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Ghoul
Well-known Member
You won't find another population injecting as much endotoxin as gear users, it's prudent to pay close attention to the growing list of problems very recent research are pointing to endotoxin as a cause or contributor to.
It's far from just Alzheimer's.
I suggest finding a hobby rather than being on every topic writing endless posts.
Are you on house arrest and this is all you do all day that you post 20 times a day ?
Each to their own but find something better to do than this. You don't get extra points in life for doing this as all this is pointless anyway.
Are you on house arrest and this is all you do all day that you post 20 times a day ?
Each to their own but find something better to do than this. You don't get extra points in life for doing this as all this is pointless anyway.
Ghoul
Well-known Member
Thanks for the advice. I invite you to find the ignore button, one click will relieve you from forum police duties.
You respond faster than customer service. That's a whole new level of dedication to the forum that you have. Or nothing else to do all day just write a bunch of endless pointless things.
You don't impress anyone doing that neither you help. You just full your ego.
Try to be around here for no more than 30 minutes and get a dog and walk outside with the rest of your time or a cat if you are on house arrest. It will be more healthy for your mind than spending 12h on a forum doesn't matter if is this forum or other forum.
But whatever makes you happy
You don't impress anyone doing that neither you help. You just full your ego.
Try to be around here for no more than 30 minutes and get a dog and walk outside with the rest of your time or a cat if you are on house arrest. It will be more healthy for your mind than spending 12h on a forum doesn't matter if is this forum or other forum.
But whatever makes you happy
poolshockguy
New Member
Repatha works wonders. Nose dived my LDL from 170 to 38 fast . Been off for 5 months and still holding steady. I stock piled 7 boxes since I don't need it anymore.
Thegodofwar
New Member
When under extreme conditions, some bacteria will form endospores to protect themselves and become "deactivated". Benzyl alcohol is a bacteriostatic agent, which "stops bacteria from reproducing, while not necessarily killing them otherwise". Without "sterilization" (not disinfection), endospores may still be able to reactivate when the correct conditions are met (body temperature) and cause infection. Certain bacteria are highly resistant to common disinfection procedures and can be deadly if allowed to grow, e.g. Clostridium botulinum, Clostridium tetani, Geobacillus stearothermophilus.
Also, besides sterilization, depyrogenation is also very important in producing anything you gonna inject into your body and should be done simultaneously with sterilization. Pyrogens are the main cause of people having fever/flu-like symptoms because it is also resistant to a lot of chemicals like IPA. In order to remove pyrogens, prepare your bottles with a high heat (constant 260 °C for two hours, without preheating) or bleach or hydrogen peroxide (both need high conc.).
This is simply a precaution to minimize the risk for the sake of one's health. It is all a matter of probability, but you are the one who will decide whether to take the risk with your own body
Ghoul
Well-known Member
I appreciate you speaking on behalf of all MESO members.
Continue exercising bold leadership by finding this:
Otherwise you risk revealing how impotent in dictating my behavior as you are.
ZyzzReincarnate
Member
The variance on the orals is pretty mad. Dont know if I should order any. Hmmm.
What are your thoughts, gentlemen?
What are your thoughts, gentlemen?
Thegodofwar
New Member
Pyrogens cause fevers most likely in this case
Ghoul
Well-known Member
Bacteria looks like it's the far easier problem to deal with, since Terminal Sterilization cures all failures to control living bacteria.
The main issues left I see to advising "just throw the vial in an oven at 160c for 2 hours" is verifying which compounds besides Test can withstand this temp, and which stoppers are compatible. Chlorobutyl stoppers is what USP advises compounders to use for injectables getting Terminally Sterilized because it's more heat resistant, but Bromobutyl stoppers seem to be more common in UGL because they're slightly cheaper.
Dealing with pyrogens/endotoxins is gonna be the harder nut to crack. They exist on any non-sterile surface. The longer the state of non-sterility, the more endotoxin bacteria leave behind.
They can't be effectively filtered out usually..
The way pharma deals with this is aseptic processing, keeping everything sterile so endotoxins are kept to a minimum in the finished product. Compounders are allowed to "brew" using non-sterile products, but there's a time limit from how long the ingredient becomes non-sterile that it can be used(hours). UGL raws are often non-sterile for years, so the endotoxin content (the "bioburden") must be huge. A mountain of bacteria waste.
As you pointed out deactivation takes really high product destroying temperature.
There might be another way though. There's work being done that demonstrates not all endotoxins are as dangerous as others. The worst of them might be deactivated at lower temps. If that's the case, something like 170c for 3 hours could Terminally Sterilize and deactivate the endotoxins we need to be most concerned with in one easy step.
And anyone who doesn't give a shit, thinks real men thrive on a little dirt in their gear, or believe it's all a FDA/big science hoax, can keep on doing what they do.
No one's trying to force you, unlike the tough guys who demand this discussion get shut down.
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Cheburek1
Member
What's Test U 250mg/ml & 350mg/ml carrier oil? Also both versions have same oil?
@Qingdao Sigma Chemicals
@Qingdao Sigma Chemicals
So, did you have it tested? Before and after? Show us the test results please.
If you don’t have concrete evidence stop lying and spreading misinformation.
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