Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

A lady I know from work is taking sema 1mg a week. She gets crazy nausea from this amount but used to take 2.4mg from the pharma pens she claims. Any other GLP suggestions?

It needs to be a strong hunger suppressant because she told me she over eats to calm herself or because of anxiety.

She is a nice lady so I’m trying to help her out here.

She doesn’t take any other medications or drink or do drugs. No health conditions besides being overweight
 
A lady I know from work is taking sema 1mg a week. She gets crazy nausea from this amount but used to take 2.4mg from the pharma pens she claims. Any other GLP suggestions?

It needs to be a strong hunger suppressant because she told me she over eats to calm herself or because of anxiety.

She is a nice lady so I’m trying to help her out here.

She doesn’t take any other medications or drink or do drugs. No health conditions besides being overweight
Tirzepetide.
It is far superior with less sides and far greater appetite suppression in my opinion.
 
A lady I know from work is taking sema 1mg a week. She gets crazy nausea from this amount but used to take 2.4mg from the pharma pens she claims. Any other GLP suggestions?

It needs to be a strong hunger suppressant because she told me she over eats to calm herself or because of anxiety.

She is a nice lady so I’m trying to help her out here.

She doesn’t take any other medications or drink or do drugs. No health conditions besides being overweight
Tirzepatide. I ran sema for over a year and was in maintenance dose for quite some time, the sides could get pretty rough sometimes. Been on tirz for about 6 weeks now with minimal sides and great appetite suppression.
 
Inventory management at QSC seems to be a mess.

On 11/11, the day the promo is announced, I order the Reta 20mg... they never respond. I follow up 2 days later and finally get a response saying the 20mg is now out of stock. I am offered the 10mg as a replacement, and I take it and pay for it.

Then today, a week later, I get an email saying the 10mg is out of stock and if I'd like to order the 15mg and take a store credit... WTF? Endless nightmare.
 
It's a frustrating, moving target. The only time I got any appetite suppression was a few years ago when I first used Sema. It was fantastic. Then the two subsequent attempts yielded no appetite suppression and constipation I didn't have the first round. Enter Tirzepatide... initially fewer sides, better regularity, but again no appetite suppression. I've attempted to increase dose, but it makes me too sick the day of injection and yields no (perceivable) benefits. I do alright without either, but having that food noise and edge taken off in deficit is really pretty damned nice. I wouldn't be against taking any for the longer-term benefits, but even 3.3mg of the Tirz makes me sick... and without actual feels, it's hard to continue. Not sure if moving up the chain to Reta is worth it, or my body has just learned to recognize this class of medication and pretty much reject it.
 
A lady I know from work is taking sema 1mg a week. She gets crazy nausea from this amount but used to take 2.4mg from the pharma pens she claims. Any other GLP suggestions?

It needs to be a strong hunger suppressant because she told me she over eats to calm herself or because of anxiety.

She is a nice lady so I’m trying to help her out here.

She doesn’t take any other medications or drink or do drugs. No health conditions besides being overweight

Just to echo what Max said. GIP acts on the brain as an anti-nauseant. But to get enough GLP will require a high dose.

If she's used to 2.4mg pharma Sema, switch her to 10mg Tirz, and if that's not getting the job done just go straight to 15 on the next dose. Luckily Tirz has fallen so much in price. You can point out it's got additional health benefits beyond Sema as well,

Normally I would recommend caution, but if she needs very strong appetite suppression and already used to 2.4mg pharma Sema, this would be an exception.

Try to make sure her doses are .5ml in volume as well.

You're doing this woman a real kindness. It speaks to your character as a man.
 
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Inventory management at QSC seems to be a mess.

On 11/11, the day the promo is announced, I order the Reta 20mg... they never respond. I follow up 2 days later and finally get a response saying the 20mg is now out of stock. I am offered the 10mg as a replacement, and I take it and pay for it.

Then today, a week later, I get an email saying the 10mg is out of stock and if I'd like to order the 15mg and take a store credit... WTF? Endless nightmare.
You gotta consider the scale of their operation. Its much larger than any of us can imagine lol. There are bound to be logistical technicalities every now and then.
 
It's a frustrating, moving target. The only time I got any appetite suppression was a few years ago when I first used Sema. It was fantastic. Then the two subsequent attempts yielded no appetite suppression and constipation I didn't have the first round. Enter Tirzepatide... initially fewer sides, better regularity, but again no appetite suppression. I've attempted to increase dose, but it makes me too sick the day of injection and yields no (perceivable) benefits. I do alright without either, but having that food noise and edge taken off in deficit is really pretty damned nice. I wouldn't be against taking any for the longer-term benefits, but even 3.3mg of the Tirz makes me sick... and without actual feels, it's hard to continue. Not sure if moving up the chain to Reta is worth it, or my body has just learned to recognize this class of medication and pretty much reject it.

Try to get back on Sema or Tirz and use the pharma dosing. protocol. Stay at each dose titration level until sides become tolerable.

This works for 95%+ of people in the pharma trials involving over 10.000+, who achieve significant weight loss that's sustained for years via a maintenance dose, with, generally, no sides and a multitude of health benefits that go beyond weight loss.

Going on and off is a bad idea. You're likely inducing immunogenicity, training your immune system to quickly clear the drug, and you may even fuck your response to naturally produced GLPs.
 
Inventory management at QSC seems to be a mess.

On 11/11, the day the promo is announced, I order the Reta 20mg... they never respond. I follow up 2 days later and finally get a response saying the 20mg is now out of stock. I am offered the 10mg as a replacement, and I take it and pay for it.

Then today, a week later, I get an email saying the 10mg is out of stock and if I'd like to order the 15mg and take a store credit... WTF? Endless nightmare.
Yeah it's a mess, sorry about that, we still have some kits rea 10mg in stock, your order will be sorted asap, please email me about it now to sigma@sigma email

Our internal communication was a mess lately, because ERP hasn't updated inventory stats compared to real inventory
 
Try to get back on Sema or Tirz and use the pharma dosing. protocol. Stay at each dose titration level until sides become tolerable.

This works for 95%+ of people in the pharma trials involving over 10.000+, who achieve significant weight loss that's sustained for years via a maintenance dose, with, generally, no sides and a multitude of health benefits that go beyond weight loss.

Going on and off is a bad idea. You're likely inducing immunogenicity, training your immune system to quickly clear the drug, and you may even fuck your response to naturally produced GLPs.
Thank you. That's what I've been wondering based on your posts... immunogenicity. It does seem to mesh with my experience. I've actually been very methodical about dosing and ramping but now seem to only experience side effects, making it impossible to increase to a point where the appetite suppression might return. I'm only a day or two outside of my weekly injection. I had started at 2.5mg (Tirz) for a month and then increased to 3.3mg for the past three weeks, but each week that injection day seems to be getting worse. I'm going to drop back to 2.5mg and stay there for longer. Might it be worth using even less?
 
Yeah it's a mess, sorry about that, we still have some kits rea 10mg in stock, your order will be sorted asap, please email me about it now to sigma@sigma email

Our internal communication was a mess lately, because ERP hasn't updated inventory stats compared to real inventory
Sent you an e-mail to tracy@sigma about another Irene fuck up. You know what, if she managed to fuck up the BPC order too just give a refund for that and the kilo of raws that your warehouse forgot to pack.
 
Just to echo what Max said. GIP acts on the brain as an anti-nauseant. But to get enough GLP will require a high dose.

If she's used to 2.4mg pharma Sema, switch her to 10mg Tirz, and if that's not getting the job done just go straight to 15 on the next dose. Luckily Tirz has fallen so much in price. You can point out it's got additional health benefits beyond Sema as well,

Normally I would recommend caution, but if she needs very strong appetite suppression and already used to 2.4mg pharma Sema, this would be an exception.

Try to make sure her doses are .5ml in volume as well.

You're doing this woman a real kindness. It speaks to your character as a man.
Hi Ghoul, I currently am using Retatrutide.
I have 20mg vials and I reconstitute with 2ml BAC water.
My current dose is 3mg so I do .3ml.
Would you recommend me to add more water?
 

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