Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[Ghoul]

Thanks man I’ll definitely check this out as an option as well. Any suggestions I’m definitely open to at this point.

Top colors don't change like a kaleidoscope, despite the disclaimer. If they did, what use are the lab reports that specify tops? Just wait for more touchdown reports in the next week or so and ask for the top colors as members chime in with their reports of getting their orders.

Hopefully the top colors will stabilize. If customs takes an interest, they're not going to be fooled by top colors or lack of a label. "Oh, this must be something wholesome!"

 

[Ghoul]

Well, it’s priced so cheap that you can viably do that as well. I just don’t want to graduate to the level of risk, myself. And don’t want to buy the equipment for brewing. So super cheap oils from QSC and filtering makes more sense for me.

I have always felt leery of ordering raws and brewing myself. I figure I am likely to get in more trouble with law enforcement by brewing raws than I am ordering finished oils. Brewing just seems like risky operation. Filtering dirt cheap vials seems like a better option for most imo.

I’m not sure if actually producing/manufacturing raws into oils carries a heavier sentence if caught. I love my gears but these wrists ain’t made for cuffs.

Although in reality enforcement is rare and done with a "light touch", in theory possession of Sched 3 drugs could land you in cuffs, court, and probation, while manufacturing Sched 3 of any amount, again in theory, could be prosecuted much more harshly, with very high mandatory minimums. It's a "top of the food chain" drug crime. But again, better to look at the big (multi million $) steroid dealing/manufacturing busts in recent years to see what really happens. (to first offenders, not much).

I'd be most worried about stepping out, god forbid my place catching fire, and the "lab" being discovered by authorities in my absence.

 

[Qingdao Sigma Chemicals]

do you have a list of any other excipients you guys add to your HGH? curious if @janoshik can identify and quantify any of it? queue in the Kurt Havens video

Serostim vs popular chinese UGL hgh since the "anabolic bodybuilding" crew and "experts" over there discuss UGL containing "polymers" probably just mannitol...

"its all the additives added to UGL hgh that change the daltons, molecular weight of the hgh, that effect absorption" - Big Paul

"when you then add Biloxone, polymers and all these other fillers it doesnt seem to absorb at the same rate, and youve changed the molecular weight of the whole thing" -Kurt Havens

"I lost 10lbs in one week when i switched back and forth from Serostim to Generics" -Chase Irons (he mentioned on instagram it was QSC hgh lol)



View: https://www.youtube.com/watch?v=K14hh2SPMNE&t=114s

We only use mannitol.
If the other excipients aren’t mentionned to janoshik it will be considered as impurity.
I remember that our past peptide engineer used to use Glycine so when we switched to him, janoshik sent us some low purity results, so when we told him that we were using Glycine excipient in these he verified the pic and it was adjusted.
And it was funny by then because he were able to detect our samples just from Glycine ratio and even can guess the resellers of our stuff.
But the engineer made a mess in 2023 and with the new one we only use mannitol.

 

[Ghoul]

Two excipient ingredient examples from pharma:

Norditropin

histidine
poloxamer 188
phenol
mannitol

Genotropin

glycine
mannitol
metacresol

Histidine and metacresol are especially significant.

In short they create an environment that prevents peptides from breaking down and reforming into aggregates. I'm not going to go into the aggregate issue here, it's been discussed in depth elsewhere, but if you understand that dimer in HGH is bad, aggregate is "super dimer" that forms after reconstitution. At the least that makes some of the peptide ineffective, can induce side effects, and rarely, can trigger an immunity to HGH that makes it ineffective (happens in about 2% of HGH recipients).

On the other hand, you can be allergic to either of these ingredients, so in that sense, if Qs HGH only has mannitol, it's more "organic" and pure.

 

[Trenbolonetax]

Two excipient ingredient examples from pharma:

Norditropin

histidine
poloxamer 188
phenol
mannitol

Genotropin

glycine
mannitol
metacresol

Histidine and metacresol are especially significant.

In short they create an environment that prevents peptides from breaking down and reforming into aggregates. I'm not going to go into the aggregate issue here, it's been discussed in depth elsewhere, but if you understand that dimer in HGH is bad, aggregate is "super dimer" that forms after reconstitution. At the least that makes some of the peptide ineffective, can induce side effects, and rarely, can trigger an immunity to HGH that makes it ineffective (happens in about 2% of HGH recipients).

On the other hand, you can be allergic to either of these ingredients, so in that sense, if Qs HGH only has mannitol, it's more "organic" and pure.

Is this a good reason to use a vial per day? Immediately use after reconstitution seems it won’t be susceptible to the same aggregate issue,

 

[Jeffholio5]

Better send me an email to tracy@sigmachemical.com.cn

my assistants can't help you that much.

I (Tracy in person) don't answer the sigma/whatsapp emails anymore, only customer service issues via tracy@sigmachemical.com.cn

That’s the email I used and received the response from. Doesn’t sound like you guys can help unfortunately since the vials have no markings on them and vial caps are random colors but i do appreciate you responding, my bad for not following the opening procedures to figure out which vial was what.

Would be nice in the future if you guys put the identifying numbers on the styrofoam that holds the vials or on the vials themselves. But now that I know the proper opening procedure I won’t make the same mistakes again.

 

[youwhat?]

Is this a good reason to use a vial per day? Immediately use after reconstitution seems it won’t be susceptible to the same aggregate issue,

Just add it to the list of reasons to use a vial a day

 

[NiMa]

That’s the email I used and received the response from. Doesn’t sound like you guys can help unfortunately since the vials have no markings on them and vial caps are random colors but i do appreciate you responding, my bad for not following the opening procedures to figure out which vial was what.

Would be nice in the future if you guys put the identifying numbers on the styrofoam that holds the vials or on the vials themselves. But now that I know the proper opening procedure I won’t make the same mistakes again.

Would be nice in the future you guy following the procedures and than all ist good.

 

[youwhat?]

Would be nice in the future you guy following the procedures and than all ist good.

Bro literally has said that 100x

 

[Ghoul]

Is this a good reason to use a vial per day? Immediately use after reconstitution seems it won’t be susceptible to the same aggregate issue,

Although I can't find it now, I read a study about aggregates in 7 different pharma rHGH formulations.

The GH that came with sterile water, not BAC, so were single dose / immediate use vials had the least aggregation and lowest rate of reported side effects.

Aggregates take time to form, an "incubation" period. The more time, the bigger they get. The larger they are, the more likely they are to cause immune reactions. That's not to say sides were definitely the result of aggregates, perhaps the lack of anti-aggregation ingredients in the immediate use formula HGH was the reason, but there's a lot of circumstantial evidence pointing to aggregates being responsible.

This applies to all peptides, by the way. The longer the chain, the more susceptible they are,

My preference is smaller dose vials of whatever peptide I'm using, so they spend the least amount of time reconstituted.

If it's a peptide used intermittently, like PT-141, hanging around for a long time, I'll filter the dose just before administration to reduce the number of large aggregates. A small reduction in potency from degradation is no big deal, but I'd rather keep the aggregates out to the extent practical.

 

[Jeffholio5]

Bro literally has said that 100x

I feel like at this point I’m mostly spamming this thread so I’m gonna step out for a while but I do appreciate everyone’s constructive feedback and assistance.

 

[Grey Spartan]

Aggregates take time to form, an "incubation" period. The more time, the bigger they get. The larger they are, the more likely they are to cause immune reactions.

Come on man. You need to tell us knuckle draggers "The incubation period for HGH is 7 days". So people like me won't order 36iu, add 3ml and take 2.4iu a day (that's 15 days a bottle for you math challenged). I know, I can take more iu's or filter but we expect more from you @Ghoul. lol

 

[Clover 0080]

I appreciate you checking man that helps me at least know the cap colors are pretty random so I’ll have to probably do some of my own testing to figure it out. I’ll probably at least figure out which ones are sustanon, mast p, and primo with the roid test kit if I’m lucky. the other two will just have to remain a mystery, I’ve ran ment before so hopefully I can figure out which one is ment from anecdotal testing then if I’m lucky I’ll have an idea which one is dhb at that point.

Lesson learned, learn from my mistakes guys don’t separate your oils from your boxes until you’re absolutely sure which one is what which and email qsc if you have questions before you do that. I may make another order sometime during a promo but I really wish there was some sort of standard for labeling the vials at qsc even if the labels were just random numbers or a QR code on the vials or caps would be awesome.

Damn I was looking forward to watching the steroid roulette play out.

 

[jasonsta]

I put 1ml of bacterio water per vial of 40ui, 3 vials which I put in a pen cartridge for a total of 120ui.
I take 6iu per day the cartridge lasts me 20 days without problem

 

[Ghoul]

Come on man. You need to tell us knuckle draggers "The incubation period for HGH is 7 days". So people like me won't order 36iu, add 3ml and take 2.4iu a day (that's 15 days a bottle for you math challenged). I know, I can take more iu's or filter but we expect more from you @Ghoul. lol

I find it comforting that the FDA's position on this is essentially (if I were writing for them):

"We know some, but not all the conditions that lead to aggregation. We don't know with certainty what the mechanisms are that lead to aggregate induced problems, but it's clear the more of that shit there is, especially the big fuckers >10um, the worse patient outcomes are, so do everything possible to minimize it."

Remember the old advice of "don't shake your peptide because it's 'fragile' and could break"? Jano did an experiment essentially disproving that.

It turns out there is something to it, but it takes time. The walls of conventional glass vials have "hot spots" of impurities that cause peptides to stick, become malformed, then aggregates "grow" on that spot. When shaken, those aggregates break loose, and now another peptide sticks to the same spot and begins growing another aggregate. So rough handling hastens aggregate formation.

And again, time is the enemy.

There are new high tech vials treated with a quartz like coating to prevent this adhesion (technically called "adsorption") and preserve peptides for longer.

Here's the same process(for the cartoon watchers here), but in a prefilled syringe where silicone lubricant is the glue making peptides stick and the aggregation process is worsened when they're knocked loose:

 

[Clyde1818]

U.S domestic have it good ! Canada dosen't even have test. No orals international

 

[bigtom343]

Well, it’s priced so cheap that you can viably do that as well. I just don’t want to graduate to the level of risk, myself. And don’t want to buy the equipment for brewing. So super cheap oils from QSC and filtering makes more sense for me.

I have always felt leery of ordering raws and brewing myself. I figure I am likely to get in more trouble with law enforcement by brewing raws than I am ordering finished oils. Brewing just seems like risky operation. Filtering dirt cheap vials seems like a better option for most imo.

I’m not sure if actually producing/manufacturing raws into oils carries a heavier sentence if caught. I love my gears but these wrists ain’t made for cuffs.

Filtering vials is also considered manufacturing in the eyes of the pigs

 

[Grey Spartan]

Filtering vials is also considered manufacturing in the eyes of the pigs

I want to call BS on this but I'm sure your right. I bet they would get you for distribution if you have more than three viles.

 

[Ghoul]

I want to call BS on this but I'm sure your right. I bet they would get you for distribution if you have more than three viles.

I mean they can charge you with whatever they want, but without direct evidence of sales it'd never stick.

Most states build their drug laws around the federal standards, and as of the new 2023 guidelines, fewer than 50 vials is a "level 6" crime, squarely in "personal use amount" territory. 1 gram of pot is "level 6".

 

[Qingdao Sigma Chemicals]

Two excipient ingredient examples from pharma:

Norditropin

histidine
poloxamer 188
phenol
mannitol

Genotropin

glycine
mannitol
metacresol

Histidine and metacresol are especially significant.

In short they create an environment that prevents peptides from breaking down and reforming into aggregates. I'm not going to go into the aggregate issue here, it's been discussed in depth elsewhere, but if you understand that dimer in HGH is bad, aggregate is "super dimer" that forms after reconstitution. At the least that makes some of the peptide ineffective, can induce side effects, and rarely, can trigger an immunity to HGH that makes it ineffective (happens in about 2% of HGH recipients).

On the other hand, you can be allergic to either of these ingredients, so in that sense, if Qs HGH only has mannitol, it's more "organic" and pure.

Metacresol is what’s responsible of the smell in geno and insulin pens