Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[mochul]

@Qingdao Sigma Chemicals Will you produce in the near future?

evolocumab​

This not simple to make. It’s not a peptide that is easily made from recombinant dna. They require professional knowledge

 

[SpaceForce]

Oh yeah because you can't mix BPC and TB together yourself because this will happen:

I tried it once. Never again.

 

[Ghoul]

This not simple to make. It’s not a peptide that is easily made from recombinant dna. They require professional knowledge

You're correct, just one clarification. To my knowledge (most, if not all) UGL peptides are fully synthesized, not the much higher investment recombinant production method.

Many peptides will be off patent and soon available as generics, This "lower cost of entry" method of synthesized peptide production is an area of research focus due to the greater immunogenicity potential from impurities that can't be detected using typical purity analysis, and the fact that synthesized peptides appear less "human" to the immune system than recombinant produced ones:

https://www.sciencedirect.com/science/article/pii/S1359644623002301

 

[BP_6]

This not simple to make. It’s not a peptide that is easily made from recombinant dna. They require professional knowledge

I was thinking something along those lines as if it were easy, we probably would have seen it by now. Most peptides are basically at the end of the day a protein chain and this is a Monoclonal antibody made through a very different process.

 

[Lifting88]

Are you allergic to the BAC or to the Sema? You may want to try a bunch of solutions.
Use a longer needle 5'16" (8mm) or 6mm at least,
Inject only bac and see of you still have lumps.
Dilute your sema concentration then inject.
Else switch vendor sema

It was from a promo with clear top
Try a new batch with pink top and everything is good...so think its from sema

 

[Ghoul]

It was from a promo with clear top
Try a new batch with pink top and everything is good...so think its from sema

Was it the same amount in the vial, out of curiosity?

 

[Megachocotone]

We'll see, maybe in december, test and primo are priorities now to get them ready, and there is a looooot of test to produce, especially with the current preorders

You got some primo coming soon? Need to know how soon I’m going to sell my kidney to pay for this.

 

[ZyzzReincarnate]

You got some primo coming soon? Need to know how soon I’m going to sell my kidney to pay for this.

Its fine man. The human body can be sustained with 75% operation of ONE kidney.

 

[somenameforme]

My international raws order arrived. Everything was finalized and confirmed on October 22, and the package arrived November 14, but is missing one uncommon item. I have contacted them about that.

The missing item issue from my earlier post has been resolved as well as it can be at the moment. Unfortunately, but unsurprisingly, the uncommon item is out of stock. I see Tracy responded to my other post, so it sounds like I just need to play the waiting game until it becomes available again.

Also, Bella is a sweetheart. Thanks for your help!

 

[Ghoul]

Also, Bella is a sweetheart. Thanks for your help!

"You're my favorite customer baby! xoxoxo"

 

[mochul]

You're correct, just one clarification. To my knowledge (most, if not all) UGL peptides are fully synthesized, not the much higher investment recombinant production method.

Many peptides will be off patent and soon available as generics, This "lower cost of entry" method of synthesized peptide production is an area of research focus due to the greater immunogenicity potential from impurities that can't be detected using typical purity analysis, and the fact that synthesized peptides appear less "human" to the immune system than recombinant produced ones:

https://www.sciencedirect.com/science/article/pii/S1359644623002301

It depends if the peptide is made through recombination or through synthetic route. Complex or/and long peptides are not easy to make.
Monoclonal antibody is not a peptide. So a total different story that i am not knowledgeable enough

 

[readalot]

Also, Bella is a sweetheart. Thanks for your help!

 

[Middus]

With the low purity of the bpc it might be a smart move for tracy to mix it up with some TB; the blends don’t get purity values on Jano tests

 

[Ghoul]

It depends if the peptide is made through recombination or through synthetic route. Complex or/and long peptides are not easy to make.
Monoclonal antibody is not a peptide. So a total different story that i am not knowledgeable enough

HGH is the only protein therapeutic I know are made via the recombinant method made available through UGLs. Makes producing kilo quantities really cheap (which might explain the rapid HGH price collapse).

I'd love to know which, if any others are (HCG maybe?), but I doubt that's something we'll ever be told.

"Out of the back door" from legit pharma API producers in China I'm guessing, which is actually a good thing if it's the case.

 

[BP_6]

HGH is the only protein therapeutic I now made via the recombinant method in UGLs. Makes producing kilo quantities really cheap (which might explain the rapid price collapse).

I'd love to know which, if any others are (HCG maybe?), but I doubt that's something we'll ever be told.

"Out of the back door" from legit pharma API producers in China I'm guessing, which is actually a good thing if it's the case.

I've always wondered that myself. Wasn't there a HGH that was made using mice cells as well? I know it was only one brand. Plus I've always wondered this pre mixed HGH AQ solutions. How they were able to make it stable much longer term in liquid form vs having to reconstitute a dry powder.

 

[Middus]

You're correct, just one clarification. To my knowledge (most, if not all) UGL peptides are fully synthesized, not the much higher investment recombinant production method.

Many peptides will be off patent and soon available as generics, This "lower cost of entry" method of synthesized peptide production is an area of research focus due to the greater immunogenicity potential from impurities that can't be detected using typical purity analysis, and the fact that synthesized peptides appear less "human" to the immune system than recombinant produced ones:

https://www.sciencedirect.com/science/article/pii/S1359644623002301

Recombinant is expensive as f!! Although wastes less fluids.

 

[Ghoul]

I've always wondered that myself. Wasn't there a HGH that was made using mice cells as well? I know it was only one brand. Plus I've always wondered this pre mixed HGH AQ solutions. How they were able to make it stable much longer term in liquid form vs having to reconstitute a dry powder.

It's all in the excipient recipe. Just the right mix of preservatives, anti-oxidants, anti-aggregation ingredients that make reconstituted HGH stable at room temperature with virtually no loss
for a month or more.

On the other hand, I saw a study that noted the HGH generics that came as a single dose vial that you reconstitute with sterile water(not BAC), and use immediately (ie, fewest or no preservatives), had the lowest reported rate of sides in the FDA tracking system.

 

[Qingdao Sigma Chemicals]

You got some primo coming soon? Need to know how soon I’m going to sell my kidney to pay for this.

preorders for it will open monday, at GB pricing

 

[Middus]

HGH is the only protein therapeutic I know are made via the recombinant method made available through UGLs. Makes producing kilo quantities really cheap (which might explain the rapid HGH price collapse).

I'd love to know which, if any others are (HCG maybe?), but I doubt that's something we'll ever be told.

"Out of the back door" from legit pharma API producers in China I'm guessing, which is actually a good thing if it's the case.

UGLs reclaim HCG from pregnant peeps pee-pee

 

[ZyzzReincarnate]

UGLs reclaim HCG from pregnant peeps pee-pee

Synthetic HCG has been available for ages