RHR difference between HGH brands

[Rbvasques]

As much as it makes sense, i wonder why on pharma hgh people also report less sides to the same dosage? @Ghoul
I have only used SSA, Hygentropin and Lobster.
Got severe sides from ssa, likely my mistake, as only did 1ml of bac water to 18iu, even though was still doing same IU dosage, was way less bac water

 

[Stubb]

As much as it makes sense, i wonder why on pharma hgh people also report less sides to the same dosage? @Ghoul
I have only used SSA, Hygentropin and Lobster.
Got severe sides from ssa, likely my mistake, as only did 1ml of bac water to 18iu, even though was still doing same IU dosage, was way less bac water

Not related to hgh but I noticed when I halved the concentration of my retatrutide reconsitution, my alledonia (skin sensitivity) reduced massively.

 

[Scottomus]

Not related to hgh but I noticed when I halved the concentration of my retatrutide reconsitution, my alledonia (skin sensitivity) reduced massively.

what did you change too?

ive got 15mg vials and using 1.5ml bac

only started last friday with 0.5mg but the nausea/sickness and now that i know what it is, alledonia. it hasnt been the best experience. im down about 12lbs in the week though as i legit cant stomach anything haha

 

[Ghoul]

what did you change too?

ive got 15mg vials and using 1.5ml bac

only started last friday with 0.5mg but the nausea/sickness and now that i know what it is, alledonia. it hasnt been the best experience. im down about 12lbs in the week though as i legit cant stomach anything haha

That sounds like an incredibly strong reaction to a microdose of Reta.

Have you used GLPs before? That sounds more like .5mg of Semaglutide.

 

[scottomus0]

That sounds like an incredibly strong reaction to a microdose of Reta.

Have you used GLPs before? That sounds more like .5mg of Semaglutide.

That was my thought process.

First time using any glps.

Got the 15mg June deal from ssa. Not really seen any feedback from anyone else though to confirm if just me, although expect they have prior experience.

Got some for others to try but only I’ve started myself so far.

Was meant to have second injection today, but I certainly don’t feel up to it!

Would you suggest 0.25mg ? Or try another source

 

[Ghoul]

As much as it makes sense, i wonder why on pharma hgh people also report less sides to the same dosage? @Ghoul
I have only used SSA, Hygentropin and Lobster.
Got severe sides from ssa, likely my mistake, as only did 1ml of bac water to 18iu, even though was still doing same IU dosage, was way less bac water

It's almost certainly just from something as simple as overdosing.

Pharma dose margins of error are kept below 5% for therapeutic proteins, and more often below 3%.

In addition, a dose that exceeds the labeled amount will fail modern QA standards. Production is designed to ensure the margin of dose error falls to the low side, rather than the high side, for safety and legal liability reasons.

So a 6mg (18iu) vial of Serostim would be between 5.8-6mg to pass QA.

UGL is more often overdosed than underdosed, and there's no precision QA going on so variation between vials can be large. I've seen 20%, and that's probably not the worst, I think SSA black top 36iu is testing at 41iu. That's a 13% overdose in one representative vial. Wouldn't surprise me if some are 45iu and others 38iu, it's only takes a difference of few drops of the solution that gets lyophilized.

There are a few more esoteric reasons why. Could be from absorption rates from high concentration or excipients causing higher peak GH (known to cause sides), or the lower likelihood of user error since pharma comes in prefilled pens or if a vial the diluent is included. But I think it's most often inadvertent overdosing.

 

[Ghoul]

That was my thought process.

First time using any glps.

Got the 15mg June deal from ssa. Not really seen any feedback from anyone else though to confirm if just me, although expect they have prior experience.

Got some for others to try but only I’ve started myself so far.

Was meant to have second injection today, but I certainly don’t feel up to it!

Would you suggest 0.25mg ? Or try another source

It's not impossible, there's always some outlier strong reaction. It's just that Sema starts at .25mg, and what you're describing sounds so close to what first timers get with that at .50mg rather than Reta, which often gets "I'm not feeling anything at 1-2mg".

But yes. assuming you reconstituted correctly go ahead and half the dose if its intolerable now.

What color are the tops?

 

[Stubb]

what did you change too?

ive got 15mg vials and using 1.5ml bac

only started last friday with 0.5mg but the nausea/sickness and now that i know what it is, alledonia. it hasnt been the best experience. im down about 12lbs in the week though as i legit cant stomach anything haha

Went from 10mg/1ml to 2ml. I am on 5mg a week though so your reaction is quite extreme.

 

[scottomus0]

It's not impossible, there's always some outlier strong reaction. It's just that Sema starts at .25mg, and what you're describing sounds so close to what first timers get with that at .50mg rather than Reta, which often gets "I'm not feeling anything at 1-2mg".

But yes. assuming you reconstituted correctly go ahead and half the dose if its intolerable now.

What color are the tops?

If it makes any difference, I did start gh at 3ius too same day.

They are blue tops

I wil continue with 0.25mg and see how I am.

I need to lick up some more electrolytes tomorrow as believe that has an impact. My water intake has suffered with how I’ve been feeling so will make sure to be on it tomorrow.

Appreciate the responses

 

[AlexDavis43]

If it makes any difference, I did start gh at 3ius too same day.

My water intake has suffered with how I’ve been feeling so will make sure to be on it tomorrow.

Water intake is important for people taking GH or GLP1

You're on both

Get on top of that water intake brother

 

[scottomus0]

I found the problem.

Swear I’m long in this game, bar glps so don’t be too harsh haha.

I was mixing both my gh and Reta. It seems v likely I’ve mixed them up.

So therefore, Instead of doing 3iu gh a day, I’ve been doing 2mg a day of Reta !!! So about 12-15mg give or take for the first week….

I’m not dead. So, but yeah. Lesson learned.

I’m assuming it’s gona be a while before it settles as it’s building in my system still.

IM A MONG LADS

 

[Ghoul]

View attachment 335404
I found the problem.

Swear I’m long in this game, bar glps so don’t be too harsh haha.

I was mixing both my gh and Reta. It seems v likely I’ve mixed them up.

So therefore, Instead of doing 3iu gh a day, I’ve been doing 2mg a day of Reta !!! So about 12-15mg give or take for the first week….

I’m not dead. So, but yeah. Lesson learned.

I’m assuming it’s gona be a while before it settles as it’s building in my system still.

IM A MONG LADS

Well now you know you can easily handle 4mg/wk, which was one of the doses that was considered as a starting point in the trials.

10 days after stopping you'll be at roughly 3-4mg equivalent blood levels and can restart at whatever dose you want to use.

 

[subzero88]

Qsc 10iu (tested at 12iu), lobster 10iu, (tested at 11iu), SSA 24iu incoming.

Even if QSC is way overdosed, which I doubt, how does that cause a +7bpm effect on RHR where Lobster had no effect on RHR. I just don't get it.

I'll hold off the tossing for now. Until I evaluated SSA and maybe I'll source some pharma gh somewhere to compare as well.

Hey man,.
Did you receive your SSA HGH? Mine should be arriving next week

 

[Stubb]

Good! Let me know. Maybe we can find a few more people to share cost for a jano test ($300). Who knows, maybe the HGH sent in by Lob is not the same stuff as we got. I haven't seen many user testing for the stuff.

Since these posts, I was on SSA 36ui for several weeks and I did not notice any increase in RHR at around 6iu (RHR seems to vary from 62-67).

Did get very mild CT symptoms when I increased the SSA dosage from 3-6iu which lasted less than a week.

Since then I've had a week off HGH and ive come back into lobsters ay 5iu with very similar CT symptoms.

No bloods to show but my feelz-reports very little differences between the two brands.

 

[Kralteramon]

Since these posts, I was on SSA 36ui for several weeks and I did not notice any increase in RHR at around 6iu (RHR seems to vary from 62-67).

Did get very mild CT symptoms when I increased the SSA dosage from 3-6iu which lasted less than a week.

Since then I've had a week off HGH and ive come back into lobsters ay 5iu with very similar CT symptoms.

No bloods to show but my feelz-reports very little differences between the two brands.

Seems like the RHR effect is very individual. I'm on 24iu SSA right now 4.5IU daily and my RHR is up 4-8 points ( between 70-74bpm on 250mg test c cruise) from baseline. I've noticed it is closely related to my sleep. If I sleep better, RHR is lower. HGH is still wrecking my sleep a bit. If I smoke a joint I'm knocked out cold and my RHR actually decreases. I've not had CT symptoms since I'm cutting, this was more an prominent during my bulk.

I know Chatgpt isn't always great but it blames my symptoms on my COMT met/met SNP and another SNP that makes me extra sensitive to HGH.

For now I've accepted the side effects and hope they will dissapear at some point. I have IGF and free t3 t4 bloodwork coming up early next week. I'm still puzzeled by the variance.

 

[Kralteramon]

Seems like the RHR effect is very individual. I'm on 24iu SSA right now 4.5IU daily and my RHR is up 4-8 points ( between 70-74bpm on 250mg test c cruise) from baseline. I've noticed it is closely related to my sleep. If I sleep better, RHR is lower. HGH is still wrecking my sleep a bit. If I smoke a joint I'm knocked out cold and my RHR actually decreases. I've not had CT symptoms since I'm cutting, this was more an prominent during my bulk.

I know Chatgpt isn't always great but it blames my symptoms on my COMT met/met SNP and another SNP that makes me extra sensitive to HGH.

For now I've accepted the side effects and hope they will dissapear at some point. I have IGF and free t3 t4 bloodwork coming up early next week. I'm still puzzeled by the variance.

Hi all, I'm back from my break briefly to share my IGF1 levels on 4.5iu SSA HGH in a slight caloric deficit and cruising on 250mg test. I'm pretty shocked by the result but also a bit relieved as it might be the cause of the side effects that I have experienced (most have subsided with the help of an MRA and melatonin). Resting heart rate still up let's say 6 points on average.

Drumroll...

IGF1: 94.4nmol/l or 723.8ng/mL
Free T3: 5.17 pmol/l
Free T4: 17.63 pmol/l
TSH: 1.37 mU/l

I think that is....a good response. I'll go back into hiding soon. Just wanted to share this and wondering if I'm blessed or cursed. I have a lot of hgh lying around and ordered a decent amount of IGF1 LR3 to try. How soon until I need new shoes? A bit worried about acromegaly lol.

 

[Ghoul]

Hi all, I'm back from my break briefly to share my IGF1 levels on 4.5iu SSA HGH in a slight caloric deficit and cruising on 250mg test. I'm pretty shocked by the result but also a bit relieved as it might be the cause of the side effects that I have experienced (most have subsided with the help of an MRA and melatonin). Resting heart rate still up let's say 6 points on average.

Drumroll...

IGF1: 94.4nmol/l or 723.8ng/mL
Free T3: 5.17 pmol/l
Free T4: 17.63 pmol/l
TSH: 1.37 mU/l

I think that is....a good response. I'll go back into hiding soon. Just wanted to share this and wondering if I'm blessed or cursed. I have a lot of hgh lying around and ordered a decent amount of IGF1 LR3 to try. How soon until I need new shoes? A bit worried about acromegaly lol.

Not sure of your age, but from 40-50, based on what's been observed, if you maintain an IGF of 723 here's a rough timeline so you can plan ahead for new shoes and gloves:

 

[readalot]

Hi all, I'm back from my break briefly to share my IGF1 levels on 4.5iu SSA HGH in a slight caloric deficit and cruising on 250mg test. I'm pretty shocked by the result but also a bit relieved as it might be the cause of the side effects that I have experienced (most have subsided with the help of an MRA and melatonin). Resting heart rate still up let's say 6 points on average.

Drumroll...

IGF1: 94.4nmol/l or 723.8ng/mL
Free T3: 5.17 pmol/l
Free T4: 17.63 pmol/l
TSH: 1.37 mU/l

I think that is....a good response. I'll go back into hiding soon. Just wanted to share this and wondering if I'm blessed or cursed. I have a lot of hgh lying around and ordered a decent amount of IGF1 LR3 to try. How soon until I need new shoes? A bit worried about acromegaly lol.

R

Post in thread 'Post up your Natty IGF-1 Level'

Sep 16, 2024

Reference Intervals for Insulin-like Growth Factor-1 (IGF-I) From Birth to Senescence: Results From a Multicenter Study Using a New Automated Chemiluminescence IGF-I Immunoassay Conforming to Recent International Recommendations

Context:. Measurement of IGF-I is a cornerstone in diagnosis and monitoring of GH-related diseases, but considerable discrepancies exist between analytical

academic.oup.com

FIG. 2
Individual points and fitted percentiles for males (right side) and females (left side). Displayed are the 2.5%, 25%, 50%, 75%, and 97.5% percentiles calculated by quantile regression via vector generalized additive models (LMS VGAM method).

Gory details: see supplemental data (link in paper)

• readalot

• 

 

[readalot]

Hi all, I'm back from my break briefly to share my IGF1 levels on 4.5iu SSA HGH in a slight caloric deficit and cruising on 250mg test. I'm pretty shocked by the result but also a bit relieved as it might be the cause of the side effects that I have experienced (most have subsided with the help of an MRA and melatonin). Resting heart rate still up let's say 6 points on average.

Drumroll...

IGF1: 94.4nmol/l or 723.8ng/mL
Free T3: 5.17 pmol/l
Free T4: 17.63 pmol/l
TSH: 1.37 mU/l

I think that is....a good response. I'll go back into hiding soon. Just wanted to share this and wondering if I'm blessed or cursed. I have a lot of hgh lying around and ordered a decent amount of IGF1 LR3 to try. How soon until I need new shoes? A bit worried about acromegaly lol.

Incredible response.

Normalized dose response curves based on clinical trials data.

R

Post in thread 'HGH Sensitivity Discussion'

Feb 26, 2025

• readalot

• 
• 

 

[Kralteramon]

Not sure of your age, but from 40-50, based on what's been observed, if you maintain an IGF of 723 here's a rough timeline so you can plan ahead for new shoes and gloves:

View attachment 343505

Crazy.. I'm in the 35-40 bracket. Hmm.. and this is continuous use? So what if I would run Hgh 6 months a year? Would it cut the time in half or even more because of some reversal in the abstinence period?