Selective Estrogen Receptor Modulators (SERMs) Review
1. Maximov PY, Lee TM, Jordan VC. The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr Clin Pharmacol. 2013;8(2):135-55. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624793/
2. Hadji P. The evolution of selective estrogen receptor modulators in osteoporosis therapy. Climacteric. 2012;15(6):513-23. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793274/
3. Goldstein SR, Siddhanti S, Ciaccia AV, Plouffe L. A pharmacological review of selective oestrogen receptor modulators. Human Reproduction Update. 2000;6(3):212-24. http://humupd.oxfordjournals.org/content/6/3/212.abstract
4. Fabian CJ, Kimler BF. Selective Estrogen-Receptor Modulators for Primary Prevention of Breast Cancer. Journal of Clinical Oncology. 2005;23(8):1644-55. http://jco.ascopubs.org/content/23/8/1644.full
5. Burris TP, Solt LA, Wang Y, Crumbley C, Banerjee S, et al. Nuclear Receptors and Their Selective Pharmacologic Modulators. Pharmacological Reviews. 2013;65(2):710-78. http://pharmrev.aspetjournals.org/content/65/2/710.full
6. Nelson ER, Wardell SE, McDonnell DP. The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosis. Bone. 2013;53(1):42-50. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552054/
7. Dutertre M, Smith CL. Molecular mechanisms of selective estrogen receptor modulator (SERM) action. J Pharmacol Exp Ther. 2000;295(2):431-7. http://jpet.aspetjournals.org/content/295/2/431.full
8. Single Doses of the SERM Lasofoxifene Increases Testosterone Levels for over 28 Days in Healthy Men. https://endo.confex.com/endo/2014endo/webprogram/Paper13945.html
9. Stokes GY, Conboy JC. Measuring Selective Estrogen Receptor Modulator (SERM) - Membrane Interactions with Second Harmonic Generation. Journal of the American Chemical Society. 2014;136(4):1409-17. http://pubs.acs.org/doi/full/10.1021/ja409250y
10. Wiehle RD, Fontenot GK, Wike J, Hsu K, Nydell J, et al. Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone. Fertil Steril. 2014;102(3):720-7. http://www.fertstert.org/article/S0015-0282(14)00537-8/abstract
11. Mazzola CR, Katz DJ, Loghmanieh N, Nelson CJ, Mulhall JP. Predicting biochemical response to clomiphene citrate in men with hypogonadism. J Sex Med. 2014;11(9):2302-7. http://onlinelibrary.wiley.com/doi/10.1111/jsm.12592/abstract
12. Ramasamy R, Scovell JM, Kovac JR, Lipshultz LI. Testosterone supplementation versus clomiphene citrate for hypogonadism: an age matched comparison of satisfaction and efficacy. J Urol. 2014;192(3):875-9. http://www.jurology.com/article/S0022-5347(14)03024-9/abstract
13. Rahnema CD, Lipshultz LI, Crosnoe LE, Kovac JR, Kim ED. Anabolic steroid-induced hypogonadism: diagnosis and treatment. Fertil Steril. 2014;101(5):1271-9. http://www.fertstert.org/article/S0015-0282(14)00140-X/abstract
14. Chua ME, Escusa KG, Luna S, Tapia LC, Dofitas B, et al. Revisiting oestrogen antagonists (clomiphene or tamoxifen) as medical empiric therapy for idiopathic male infertility: a meta-analysis. Andrology. 2013;1(5):749-57. http://onlinelibrary.wiley.com/doi/10.1111/j.2047-2927.2013.00107.x/full
15. Kaminetsky J, Werner M, Fontenot G, Wiehle RD. Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel. J Sex Med. 2013;10(6):1628-35. http://onlinelibrary.wiley.com/doi/10.1111/jsm.12116/abstract
16. Moskovic DJ, Katz DJ, Akhavan A, Park K, Mulhall JP. Clomiphene citrate is safe and effective for long-term management of hypogonadism. BJU Int. 2012;110(10):1524-8. http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.10968.x/full
17. Birzniece V, Sutanto S, Ho KK. Gender difference in the neuroendocrine regulation of growth hormone axis by selective estrogen receptor modulators. J Clin Endocrinol Metab. 2012;97(4):E521-7. http://press.endocrine.org/doi/abs/10.1210/jc.2011-3347
18. Birzniece V, Sata A, Sutanto S, Ho KK. Neuroendocrine regulation of growth hormone and androgen axes by selective estrogen receptor modulators in healthy men. J Clin Endocrinol Metab. 2013;95(12):5443-8. http://press.endocrine.org/doi/full/10.1210/jc.2010-1477
19. Nilsson S, Makela¤ S, Treuter E, Tujague M, Thomsen J, et al. Mechanisms of Estrogen Action. Physiological Reviews. 2001;81(4):1535-65. http://physrev.physiology.org/content/81/4/1535
20. Tsourdi E, Kourtis A, Farmakiotis D, Katsikis I, Salmas M, et al. The effect of selective estrogen receptor modulator administration on the hypothalamic-pituitary-testicular axis in men with idiopathic oligozoospermia. Fertil Steril. 2009;91(4 Suppl):1427-30. http://www.fertstert.org/article/S0015-0282(08)01280-6/abstract
21. Doran PM, Riggs BL, Atkinson EJ, Khosla S. Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. J Bone Miner Res. 2001;16(11):2118-25. http://onlinelibrary.wiley.com/doi/10.1359/jbmr.2001.16.11.2118/full
1. Maximov PY, Lee TM, Jordan VC. The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr Clin Pharmacol. 2013;8(2):135-55. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624793/
2. Hadji P. The evolution of selective estrogen receptor modulators in osteoporosis therapy. Climacteric. 2012;15(6):513-23. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793274/
3. Goldstein SR, Siddhanti S, Ciaccia AV, Plouffe L. A pharmacological review of selective oestrogen receptor modulators. Human Reproduction Update. 2000;6(3):212-24. http://humupd.oxfordjournals.org/content/6/3/212.abstract
4. Fabian CJ, Kimler BF. Selective Estrogen-Receptor Modulators for Primary Prevention of Breast Cancer. Journal of Clinical Oncology. 2005;23(8):1644-55. http://jco.ascopubs.org/content/23/8/1644.full
5. Burris TP, Solt LA, Wang Y, Crumbley C, Banerjee S, et al. Nuclear Receptors and Their Selective Pharmacologic Modulators. Pharmacological Reviews. 2013;65(2):710-78. http://pharmrev.aspetjournals.org/content/65/2/710.full
6. Nelson ER, Wardell SE, McDonnell DP. The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosis. Bone. 2013;53(1):42-50. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552054/
7. Dutertre M, Smith CL. Molecular mechanisms of selective estrogen receptor modulator (SERM) action. J Pharmacol Exp Ther. 2000;295(2):431-7. http://jpet.aspetjournals.org/content/295/2/431.full
8. Single Doses of the SERM Lasofoxifene Increases Testosterone Levels for over 28 Days in Healthy Men. https://endo.confex.com/endo/2014endo/webprogram/Paper13945.html
9. Stokes GY, Conboy JC. Measuring Selective Estrogen Receptor Modulator (SERM) - Membrane Interactions with Second Harmonic Generation. Journal of the American Chemical Society. 2014;136(4):1409-17. http://pubs.acs.org/doi/full/10.1021/ja409250y
10. Wiehle RD, Fontenot GK, Wike J, Hsu K, Nydell J, et al. Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone. Fertil Steril. 2014;102(3):720-7. http://www.fertstert.org/article/S0015-0282(14)00537-8/abstract
11. Mazzola CR, Katz DJ, Loghmanieh N, Nelson CJ, Mulhall JP. Predicting biochemical response to clomiphene citrate in men with hypogonadism. J Sex Med. 2014;11(9):2302-7. http://onlinelibrary.wiley.com/doi/10.1111/jsm.12592/abstract
12. Ramasamy R, Scovell JM, Kovac JR, Lipshultz LI. Testosterone supplementation versus clomiphene citrate for hypogonadism: an age matched comparison of satisfaction and efficacy. J Urol. 2014;192(3):875-9. http://www.jurology.com/article/S0022-5347(14)03024-9/abstract
13. Rahnema CD, Lipshultz LI, Crosnoe LE, Kovac JR, Kim ED. Anabolic steroid-induced hypogonadism: diagnosis and treatment. Fertil Steril. 2014;101(5):1271-9. http://www.fertstert.org/article/S0015-0282(14)00140-X/abstract
14. Chua ME, Escusa KG, Luna S, Tapia LC, Dofitas B, et al. Revisiting oestrogen antagonists (clomiphene or tamoxifen) as medical empiric therapy for idiopathic male infertility: a meta-analysis. Andrology. 2013;1(5):749-57. http://onlinelibrary.wiley.com/doi/10.1111/j.2047-2927.2013.00107.x/full
15. Kaminetsky J, Werner M, Fontenot G, Wiehle RD. Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel. J Sex Med. 2013;10(6):1628-35. http://onlinelibrary.wiley.com/doi/10.1111/jsm.12116/abstract
16. Moskovic DJ, Katz DJ, Akhavan A, Park K, Mulhall JP. Clomiphene citrate is safe and effective for long-term management of hypogonadism. BJU Int. 2012;110(10):1524-8. http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.10968.x/full
17. Birzniece V, Sutanto S, Ho KK. Gender difference in the neuroendocrine regulation of growth hormone axis by selective estrogen receptor modulators. J Clin Endocrinol Metab. 2012;97(4):E521-7. http://press.endocrine.org/doi/abs/10.1210/jc.2011-3347
18. Birzniece V, Sata A, Sutanto S, Ho KK. Neuroendocrine regulation of growth hormone and androgen axes by selective estrogen receptor modulators in healthy men. J Clin Endocrinol Metab. 2013;95(12):5443-8. http://press.endocrine.org/doi/full/10.1210/jc.2010-1477
19. Nilsson S, Makela¤ S, Treuter E, Tujague M, Thomsen J, et al. Mechanisms of Estrogen Action. Physiological Reviews. 2001;81(4):1535-65. http://physrev.physiology.org/content/81/4/1535
20. Tsourdi E, Kourtis A, Farmakiotis D, Katsikis I, Salmas M, et al. The effect of selective estrogen receptor modulator administration on the hypothalamic-pituitary-testicular axis in men with idiopathic oligozoospermia. Fertil Steril. 2009;91(4 Suppl):1427-30. http://www.fertstert.org/article/S0015-0282(08)01280-6/abstract
21. Doran PM, Riggs BL, Atkinson EJ, Khosla S. Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. J Bone Miner Res. 2001;16(11):2118-25. http://onlinelibrary.wiley.com/doi/10.1359/jbmr.2001.16.11.2118/full
