MESO-Rx Sponsor Steroidify - Official Worldwide Pharma Distributor since 2008

[Steroidify Rep]

Bloodwork – What to look for?

If you’re willing to start a cycle, the best advice in theory is to look for a doctor to help you with it. Sounds easy, but in practice not many doctors are willing to aid in the task of making sure you do the least damage to your body while using PEDs. If you’re lucky enough to find one that’s willing to cope with steroid use, it probably won’t come cheap. Your second-best bet is to learn yourself how to check if your body is working as it should at least at a basic level. One way to do it is by doing your blood work regularly, especially before, during and after the use of hormones. Here’s what you should look for:

1 - Complete blood count (CBC): A CBC consists of a group of tests that evaluate the various cells that circulate in the body, both in quantity and quality, including red blood cells, white blood cells and platelets. These parameters can help evaluate overall health and detect a variety of diseases and conditions early on.

2 - Comprehensive Metabolic Profile (CMP): The purpose of a CMP is to conduct a broad assessment of various aspects of physical well-being. With 14 measurements, it can detect a range of abnormalities in blood sugar, nutrient balance, liver and kidney health. It consists of glucose, calcium, sodium, potassium, bicarbonates, chloride, blood urea nitrogen, creatinine, albumin, total protein, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase and bilirubin tests.

3 - Dosage of Estradiol (E2): Especially useful in the middle of testosterone-based cycles as E2 levels tend to rise as testosterone is converted into estradiol (female hormone) by a process called aromatization. May help you choose whether or not to include an anti-aromatase drug in your protocol.

4 - Follicle-Stimulating Hormone (FSH): FSH is made by your pituitary gland, a small gland located underneath the brain. FSH plays an important role in sexual development and functioning. In men, FSH helps control the production of sperm. During a cycle, FSH production tends to decrease drastically, so keeping track of your levels might help decide on the inclusion of countermeasures if necessary.

5 - Complete Lipid Panel with LDL to HDL ratio: Every steroid has the ability change an individual’s lipid profile to some extent, so it’s always a good idea to never stop doing cardio and include healthy oily fish and other sources of omega 3 in your diet. This test shows every lipid parameter in the body, which can be helpful as staying in a dyslipidemia state for a long extent of time is one of the main factors for cardiac events. Other conditions such as pancreatic failure can also be foreseen by unbalance in lipids.

6 - Luteinizing Hormone (LH): LH helps your reproductive system function as it should: cellularly, it indicates the function of a woman’s ovaries and a man’s testes. It’s also called lutropin and interstitial cell stimulating hormone. It’s made in your pituitary gland, which sits just behind your nose. An LH test may be helpful for reversing an infertility situation or to check for a pituitary gland problem.

7 - Progesterone: In men, progesterone is produced in adrenal and testicular tissue. It is the precursor to cortisol, testosterone, estrogen and other hormones. May indicate the beginning of a gynecomastia condition.

8 - Testosterone, total and free: Useful before a cycle to see your base levels, during to see how much has risen with your particular gear/dosage and after 45/60 days of completing a PCT to see how much of your natural production has bounced back.

9 - Thyroid Stimulating Hormone (TSH), T4, T3: These should all work in tandem if you have a healthy thyroid, so this test may come in handy if you’re suspecting your thyroid isn’t working as it should or if you’ve taken or is taking T3, T4 or other hormones of this kind.

Please keep in mind that a blood panel is like a snapshot of your body: it will give you a pretty good idea of what’s happening, but you can’t really make a verdict out of it. For that, it’s best to take several blood samples and see if the pattern holds. At that point, if any suspicion arises, it’s probably best to go see a doctor.

This panel is the basic a person looking to start a cycle should get, but of course there are more complete (and more expensive) tests out there: which may include IGF-1 and HGH levels, specific enzymes, glycemic curves, cortisol, several vitamins, etc. and are just too specific to be covered here.

https://steroidify.blog/health-science/bloodwork-what-to-look-for/

 

[Steroidify Rep]

Periodization Basics – What is it and why you should do it

Have you ever felt like you hit a plateau in the gym? In order to keep gaining both strength and size, sometimes you can’t just keep increasing volume and intensity. Often times the best way to keep evolving is to give yourself a break, let your body adapt and consolidate your gains in order to keep going forward.

However, as you may have guessed, there are many and many different ways to program these breaks and how to get back into training in order to evolve at the maximum possible rate. Throughout the history of resisted training, different professionals of various countries have developed several methods and it is no easy task to simply pick “the best”, as you have to keep in mind the intensity of training, the total and periodic volumes, the metabolic and central nervous system impact of the proposed program, among many other variables.

Although this concern with the organization of training is more important for competitive athletes in categories such as powerlifting, Olympic weightlifting, strength sports and any other high-performance activity that benefits from resisted training, bodybuilders can apply the concepts to maximize expected results in terms of strength and size in the least amount of time possible.

Formally, the term periodization refers to a way of organizing training into basic workable units. From the shortest to the longest, these units are organized as the training session, the microcycle, the mesocycle, the macrocycle and the quadrennial. Let’s define and detail each one of these:

- The training session: it’s the structural unit of training, designed to fulfill a specific purpose, such as training a particular muscle group, lifting a certain amount of weight in a specific movement for a given number of repetitions, or serving a restorative/recovery goal;

- The microcycle: usually consists of 2 to 9 training sessions with different individual purposes, with 7 being the average, or simply a week of training. Usual microcycles are the introductive, restorative, competitive and shock microcycles;

- The mesocycle: this cycle is made up of many microcycles designed around one purpose, usually a component of fitness such as strength, power, endurance, hypertrophy or other physical ability or even focus on the quality and technique of the exercise. Lasts from one month to about 4 months;

- The macrocycle: consists of many mesocycles, usually comprising the whole season of an athlete and lasting about a year. It’s the medium-term cycle where goals will be set for the competitive period and a decently built macrocycle will prepare the athlete for the new season;

- The quadrennial: originally thought for olympic cycle, hence the 4-year period. This is the long-term planning where the correction of major flaws like disproportions should be addressed, longevity of training and the overall development of the program.

One major problem today is that many training sessions we see around in the gym have no specific purpose that leads to the short or long-term goals of the person, all the way from beginners to advanced gym-goers. In order to develop and fulfill the desired purpose of training, each training session must build on the others and not just go to the gym and do whatever you feel like doing.

In the end, if you build yourself a nice, periodized training plan and stick to it, you will find that you will develop at a much faster rate than if you don’t. Of course, a periodization plan isn’t static, and can be changed and adapted as you go because, as we all know, life is full of surprises and an injury, for example, can make you replan everything in your life.

https://steroidify.blog/training/periodization-basics-what-is-it-and-why-you-should-do-it/

 

[Steroidify Rep]

BTW Labs Has Officially Landed In The US 25% OFF

The wait is over. BTW Labs has officially landed at US Premium Warehouse 1, bringing lab-tested excellence straight to your doorstep. No customs, no delays, no BS.

With a 25% discount to celebrate our US arrival.

Visit link below and take advantage now:

https://steroidify.ltd/news/domestic-domination

All the lab tests for these are here, guys:

https://steroidify.ltd/labtests

Local shipping with a 25% discount and premium quality. Can't beat it.

 

[Steroidify Rep]

Does Trenbolone cause Alzheimer’s?

Trenbolone (also known as Trienolone and Trienbolone) is a Nandrolone (19-Nortestosterone) derivative and perhaps the most infamous AAS ever developed.

It was first synthesized from Nandrolone in the late 1960s and starting in the early 1970s it was sold for the purpose of growing lean mass and increasing appetite in cattle.

Trenbolone was adopted by bodybuilders as a contest prep agent in the 1980s, and it has remained the king of cutting AAS ever since.

Its powerful, versatile nature and potentially devastating side-effects have turned it into one of the most feared yet appealing AAS on the market, with thousands of people risking their health to get insane results from it.

What benefits can one expect from it? Well, other than a ridiculous increase in lean muscle tissue and strength, one will experience improved vascularity, muscle hardness, fat loss, libido and even confidence. It is not uncommon for enhanced bodybuilders to claim that Trenbolone causes a “god-like” feeling.

Unfortunately, it is not all fun and games.

In terms of side-effects, Trenbolone is infamous for causing aggression, damaging the organs, making it hard to sleep properly and increasing prolactin levels by acting as a progestin, but one of the most serious aspects of Trenbolone that does not get much attention is the effect it has on the brain.

According to animal (rat) studies, Trenbolone is able to cross the blood-brain barrier and induce apoptosis of primary hippocampal neurons while increasing the concentration of a protein known as A-Beta-42.

https://pubmed.ncbi.nlm.nih.gov/25461682/

In other words, Trenbolone kills neurons in the hippocampus, which is the region of the brain that controls both short-term and long-term memory. Furthermore, high AB42 concentrations have been linked to Alzheimer’s disease. [R]

https://pubmed.ncbi.nlm.nih.gov/9789825/

This is incredibly concerning, because it means that repeated Trenbolone use could seriously affect one’s memory, promote neurodegeneration and increase the chances of developing dementia or Alzheimer’s later in life.

What is also concerning is that in this study, not even Testosterone and estradiol were able to protect the brain from Trenbolone, meaning that the theory that keeping estradiol levels slightly high on Trenbolone to prevent brain damage is NOT valid.

But is all hope lost? Is it possible to use avoid or at least mitigate this terrible side-effect?

The truth is we don’t know. We could theorize that supplementing with neuroprotective nootropics that stimulate memory by increasing the expression of neurotransmitters like glutamate and acetylcholine in the hippocampus MAY counteract the neurotoxicity of Trenbolone, but this is just a theory that has never been studied.

A possible solution may be Oxiracetam, which has been shown to decrease the expression of the protein A-Beta-42 (which is linked to Alzheimer’s and which Trenbolone increases).

https://pubmed.ncbi.nlm.nih.gov/32765394/

In our opinion, athletes who want (or rather NEED) to use Trenbolone should consider supplementing with nootropics like Oxiracetam + Alpha-GPC and limit Trenbolone use as much as possible to prevent long-term brain damage.

https://steroidify.blog/hormones-peds/does-trenbolone-cause-alzheimers/

 

[Steroidify Rep]

Muscle memory: how powerful is it and how does it work?

Muscle memory is a popular concept in fitness, often described as the body’s ability to “remember” previous muscle size and strength levels, allowing for quicker recovery after a period of inactivity. But just how real is this idea? What happens to your muscles during a long break, and how does muscle memory really work? This article explores the science behind muscle memory and what you can expect after interrupting your regular training routine for different amounts of time.

Generally speaking, muscle memory refers to the body’s ability to regain muscle mass and strength more quickly after a period of inactivity. It’s not just a motivational concept; it’s grounded in biological science, involving two primary mechanisms: neurological adaptations and muscle cell changes. Here’s how each one of them works:

Neurological adaptations

When you begin strength training, your nervous system becomes more efficient at recruiting muscle fibers, coordinating movements, and generating force. These neurological adaptations are crucial for improving strength and muscle control. Even during long breaks, these adaptations persist, which is why people often find it easier to get back into their older form when they return to training.

Muscle cell changes

Muscle cells are unique in that they can add more nuclei (called myonuclei) as they grow in size. These myonuclei are responsible for controlling protein synthesis and cellular repair, playing a key role in hypertrophy (muscle growth). Notably, once muscle cells gain these nuclei, they tend to keep them, even if the muscle shrinks due to inactivity. This retention is the core of muscle memory, allowing for faster muscle regrowth when you resume training.

When you stop training for a period, changes occur in your body and muscles:

Muscle atrophy

Muscle atrophy, or the shrinking of muscle fibers, starts within weeks of inactivity due to reduced protein synthesis and increased breakdown. However, the muscle cells retain their added nuclei, allowing for quicker regrowth when you resume training.

Strength loss

Strength loss is slower than muscle atrophy because neurological adaptations last longer. Your muscles may look and feel smaller, but your strength doesn’t decline as rapidly, making it easier to regain previous strength levels.

Metabolism changes

Extended breaks can lead to metabolic shifts, like reduced insulin sensitivity and increased fat storage, making body composition harder to maintain. While these changes can be harder to overcome, muscle memory still aids in faster recovery of fitness levels with proper diet and exercise.

The length of your break significantly influences how muscle memory functions and how quickly you can regain your previous muscle mass and strength:

Short-term breaks (1-4 weeks)

Minimal muscle atrophy occurs, and most gains are preserved. Strength remains stable, allowing you to resume training with little to no loss in performance or muscle size.

Moderate breaks (1-3 months)

Muscle atrophy and strength loss become more noticeable, but muscle memory helps you quickly regain most of your previous size and strength within a few weeks of consistent training.

Long-term breaks (3+ months)

Significant muscle atrophy and strength loss occur, but muscle memory enables quicker regrowth once training resumes, making recovery faster than starting from scratch.

When you return to training after an extended break, it’s essential to approach your workouts with a plan to maximize the benefits of muscle memory:

Start slow

Gradually increase intensity to allow your body to re-adapt.

Compound movements

Exercises like presses, rows, squats and deadlifts engage multiple muscles, helping you regain strength and size faster.

Recovery

Proper rest, nutrition, and hydration are crucial for rebuilding muscle.

Consistency

Regular training is key to regaining your previous gains quickly.

Muscle memory is a scientifically validated phenomenon that explains why it’s easier to regain muscle mass and strength after a break than it was to build them in the first place. The retention of myonuclei and neurological adaptations are the primary mechanisms behind this process. While long periods of inactivity can lead to muscle loss and reduced strength, all the work done in previous training allow for quicker recovery once you resume.

So, in conclusion, muscle memory is a powerful tool that enables you to bounce back from extended breaks with greater ease than many might expect. While inactivity can result in muscle atrophy and strength loss, your body naturally has the ability to regain these losses more quickly thanks to the biological mechanisms of muscle memory. By approaching your return to training with a strategic plan (starting slowly, focusing on compound movements, prioritizing recovery, and maintaining consistency), you can rebuild your physique and strength faster and more effectively, ensuring that your hard work in the gym is never completely lost.

__________________________________________________

https://steroidify.blog/health-science/muscle-memory-how-powerful-is-it-and-how-does-it-work/