Sublingual T

zkt

New Member
My wife and I went to Walmart yesterday and for some reason I started sucking on a pouch of Agel. In about an hour or so I started feeling a bit horney. It sure wasnt the eye candy at WM that was causative so it might have been the T.
So Ive been wondering about SL dosing.
Specifically what % of the dose ends up in the b;lood stream and how long it takes to reach maximum serum concentration.
I would guess that a significant proportion of the dose is absorbed. Much more than transdermally. Maybe as high as 80%? Of course, the carrier has a lot to do with it. The Etoh in Agel is absorbed very well.
Anyone have any thoughts or experience?
 
My wife and I went to Walmart yesterday and for some reason I started sucking on a pouch of Agel. In about an hour or so I started feeling a bit horney. It sure wasnt the eye candy at WM that was causative so it might have been the T.
So Ive been wondering about SL dosing.
Specifically what % of the dose ends up in the b;lood stream and how long it takes to reach maximum serum concentration.
I would guess that a significant proportion of the dose is absorbed. Much more than transdermally. Maybe as high as 80%? Of course, the carrier has a lot to do with it. The Etoh in Agel is absorbed very well.
Anyone have any thoughts or experience?

Ok...explain yourself.

Why were you sucking on the pouch of androgel? DId you have it in your pocket from earlier and were so bored you decided to stick it in your mouth?

Also, did you see Scally at WalMart? (Mike, I am not going to let this go :) )
 
My wife and I went to Walmart yesterday and for some reason I started sucking on a pouch of Agel. In about an hour or so I started feeling a bit horney. It sure wasnt the eye candy at WM that was causative so it might have been the T.
So Ive been wondering about SL dosing.
Specifically what % of the dose ends up in the b;lood stream and how long it takes to reach maximum serum concentration.
I would guess that a significant proportion of the dose is absorbed. Much more than transdermally. Maybe as high as 80%? Of course, the carrier has a lot to do with it. The Etoh in Agel is absorbed very well.
Anyone have any thoughts or experience?

 
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Ok...explain yourself.

Why were you sucking on the pouch of androgel? DId you have it in your pocket from earlier and were so bored you decided to stick it in your mouth?

Also, did you see Scally at WalMart? (Mike, I am not going to let this go :) )



No I didnt see Dr. Scally. In my part of the country all you see at Walmart is lardasses, which is how I know that the Tgel was probably responsible for the effect.
Basically, yes, that was what happened.
No, thats not exactly true. I admitably was feeling a bit less perky than usual and and actually went back to the house to get it so I could do this little experiment.
 
How did it taste? I don't think it is a real suitable option. The absorption through the membranes in the mouth is only part of the picture. How much gets stuck in saliva and accidentally swallowed? Then you are dealing with membranes in the esophagus.

Now that I am thinking about it, why don't people put it on the tops of their feet? Thin skin, and no contact to other people. Also if you use testim it would just smell up your socks, not your entire shirt. The downside would be that the feet get relatively poor bloodflow. I am not sure how this fits in. Someone should try it.
 
How did it taste? I don't think it is a real suitable option. The absorption through the membranes in the mouth is only part of the picture. How much gets stuck in saliva and accidentally swallowed? Then you are dealing with membranes in the esophagus.

Now that I am thinking about it, why don't people put it on the tops of their feet? Thin skin, and no contact to other people. Also if you use testim it would just smell up your socks, not your entire shirt. The downside would be that the feet get relatively poor bloodflow. I am not sure how this fits in. Someone should try it.

Kinda like grain alcohol or even gin. Got to go slow or else it`ll burn like hell. No doubt part is swallowed and rendered useless. Dont count this out yet. I`m not the only crazy guy here. It would be simple kitchen chemistry to evaporate the Etoh out and make a hard candy.
Gotta think outside the box. Bettter yet screw the box.
Good idea about the tops of the feet. When it warms up to flip-flop weather maybe I`ll give it a try.
 
It is a bad idea to eat Androgel on a regular basis because that would be about as toxic as eating any other cosmetic "vanishing gel" type product. Ingredients include lye and isopropyl myristate (rust remover/penetrant.)

Absorption is very fast; about 20 minutes at most. You don't need the alcohol and penetrating oils. If you want to experiment with sublingual testosterone, use the troches made specifically for that purpose, or have something compounded.

The sublingual testosterone I use is 25mg/ml. 3-4 drops is the proper dose. The effect is seen within minutes. Note that this provdes about 3mg of total testosterone into the mouth. The absorption into the blood is less than 50% -- a normal human male only produces 7mg endogenously throughout the day.

As an aside, though -- is this place really turning into a forum of men who eat Androgel or bring syringes of testosterone to bars because they aren't feeling "perky" enough or they think it'll help their boner?
 
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It is a bad idea to eat Androgel on a regular basis because that would be about as toxic as eating any other cosmetic "vanishing gel" type product. Ingredients include lye and isopropyl myristate (rust remover/penetrant.)

Absorption is very fast; about 20 minutes at most. You don't need the alcohol and penetrating oils. If you want to experiment with sublingual testosterone, use the troches made specifically for that purpose, or have something compounded.

The sublingual testosterone I use is 25mg/ml. 3-4 drops is the proper dose. The effect is seen within minutes. Note that this provdes about 3mg of total testosterone into the mouth. The absorption into the blood is less than 50% -- a normal human male only produces 7mg endogenously throughout the day.

As an aside, though -- is this place really turning into a forum of men who eat Androgel or bring syringes of testosterone to bars because they aren't feeling "perky" enough or they think it'll help their boner?

The lye (sodium hydroxide) is used to adjust the ph. Not sure about the isopropyl myristate but it doesnt matter if its absorbed into the skin or the mucus membrane of the mouth. From there it goes into the extra-cellular fluid and then into the venous capillaries and the systemic circulation.
1 drop=0.05 ml
Yes, youre right the dose was too high.
Also the half life is about 70 min
Thanks for the useful info.
This forum is and has been for as long as I`ve been here, a place to intelligently discuss whatever one wants to discuss that related to medical matters. If there is something you want to discuss simply start a thread.
 
As an aside, though -- is this place really turning into a forum of men who eat Androgel or bring syringes of testosterone to bars because they aren't feeling "perky" enough or they think it'll help their boner?

Says the guy who uses sublingual drops for the same purpose?
 
Says the guy who uses sublingual drops for the same purpose?

Yes. Because: pure testosterone sublingual drops will actually cause an immediate boost in testosterone and therefore might have an effect. I'm poking fun at the gentleman who was injecting tiny amounts of testosterone ester rather than pure testosterone, thinking it would have an effect -- and not only that -- but promoting it as effective (even though the same guy is on 8 different medications.)
 
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Yes. Because: pure testosterone sublingual drops will actually cause an immediate boost in testosterone and therefore might have an effect. I'm poking fun at the gentleman who was injecting tiny amounts of testosterone ester rather than pure testosterone, thinking it would have an effect -- and not only that -- but promoting it as effective (even though the same guy is on 8 different medications.)

If I poked fun at every stupid comment I read here I wouldnt have time left to say anything worthwhile or helpful. :(
 
And another thing:
Ever hear of the plecebo effect?
If he thinks that a poke of ester will help his libido and/or self confidence in a bar situation- it probably does.
I used to flame the dumbest poster of the day- I dont do that any more-much.
May peace and harmony come your way
 
And another thing:
Ever hear of the plecebo effect?
If he thinks that a poke of ester will help his libido and/or self confidence in a bar situation- it probably does.
I used to flame the dumbest poster of the day- I dont do that anymore-much.
May peace and harmony come your way
 
Sure, this works. The T liquid James mentioned is a good way to do it instead of fooling around with a dermal mix. There was another thread where someone was complaining about the taste of 25mg T per ml propylene glycol. It might not taste good, but it isnt toxic and it will give you a temporary kick in the pants. Not suitable for TRT, just for intermittent boosting when you need it. And I dont believe the level is high enough for transfer to be much of a concern. Some ladies could use a microdose of T every now and then anyway.

Whatever happened to T lozenges? They work too if you dont mind a tablet stuck above your canine all freakin day. Too much of a pain in the ass?
 
Sure, this works. The T liquid James mentioned is a good way to do it instead of fooling around with a dermal mix. There was another thread where someone was complaining about the taste of 25mg T per ml propylene glycol. It might not taste good, but it isnt toxic and it will give you a temporary kick in the pants. Not suitable for TRT, just for intermittent boosting when you need it. And I dont believe the level is high enough for transfer to be much of a concern. Some ladies could use a microdose of T every now and then anyway.

Whatever happened to T lozenges? They work too if you dont mind a tablet stuck above your canine all freakin day. Too much of a pain in the ass?

I`ll try most anything once. Got a link?
 
I'm not aware of anthing commercially available, but I havent looked either.

A compounding pharmacy can make them for you.
 
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