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T3 has a role in promoting cartilage maturation/differentiation. It shouldn't have any negative impact....positive if anything. T3 is said to be "catabolic", but that term can describe many different ways of accomplishing the same net results. T3, I believe, doesn't raise cortisol levels.Ronin_ said:I was thinking of running 25mcg ED for 6-8 weeks whilst off cycle to cut up some. Is it actually bad for your connective tissue?