Sema/Thriz/Reta choices

[Here2Learn]

Currently I’m on Sema, up to 1.25mg/week and have been losing an average of 1lb/week or less. I started at a medspa, just shifted to Skye and now researching China direct. My inflammation can vary widely so the scale jumps all over the place. Sema has helped with inflammation and I’m looking into running BPC/TB for. 6-8 week protocol to see if it helps more and than a series of Thymosin Alpha 1 after that.

My question is with the lower pricing of China direct Tirz/Reta is more affordable so it has become and option. Sema makes me SO tired and I feel like some weeks it works really well and other weeks not as much. If you were to change what would you choose? I’ve researched all of them pretty extensively so I know the pro/cons but looking for people who have switched and what they liked or don’t like.

 

[Here2Learn]

I only know my personal experience as a woman. I was following a 1st Phorm lifting program 6 days a week plus doing light cardio 7 days. I tracked ever morsel of food, eating very clean, for a year and I gained and lost the same 5 pounds. I started Sema and I instantly, I mean within 3 days, lost inflammation like crazy. My face shrunk considerably to the point the doc was shocked. Something more than willpower over my eating going on.

 

[Clover 0080]

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

www.news-medical.net

Unveiling the Therapeutic Potential: GLP-1 Medications and Their Anti-Inflammatory Effects

www.ayafusion.com

So many new studies coming out about how GLP1s act on inflammation in the body. its crazy how much more they do than just glucose control and weightless

 

[Here2Learn]

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

www.news-medical.net

Unveiling the Therapeutic Potential: GLP-1 Medications and Their Anti-Inflammatory Effects

www.ayafusion.com

So many new studies coming out about how GLP1s act on inflammation in the body. its crazy how much more they do than just glucose control and weightless

This right here is why I started down the peptide journey. I really knew nothing about peptides but when my inflammation was eased I wanted to know what else was out there.

Recently I started a new batch Sema from Skype peptides and I have had the worst hip and back pain. My inflammation has come back, maybe not the degree as before but definitely back, and I don’t think it is a good batch. I micro dosed Reta for the first time, also from Skye, and it definitely worked. Got the cold sensation and felt some anxiety after taking it. Can’t wait for my new batch, China direct vendor, to come in so I can get on Tirz and see what it does for inflammation. Very disappointed in Skye at the moment though.

 

[Clover 0080]

oh man tirz is the absolute winner for everything. Your going to be a whole new person. I will always recommend tirz over sema and reta. No harsh side effects but all the good benefits.

 

[Here2Learn]

oh man tirz is the absolute winner for everything. Your going to be a whole new person. I will always recommend tirz over sema and reta. No harsh side effects but all the good benefits.

The exhaustion got so bad on Sema I had to figure out something different! Should be here in a week or so.

 

[reride2020]

Where are you getting your tirz

 

[reride2020]

oh man tirz is the absolute winner for everything. Your going to be a whole new person. I will always recommend tirz over sema and reta. No harsh side effects but all the good benefits.

Where are you getting you tirz?

 

[PiscesMoon]

My question is with the lower pricing of China direct Tirz/Reta is more affordable so it has become and option. Sema makes me SO tired and I feel like some weeks it works really well and other weeks not as much. If you were to change what would you choose? I’ve researched all of them pretty extensively so I know the pro/cons but looking for people who have switched and what they liked or don’t like.

It seems like the week before, during, and after one's menstruation cycle may be a time frame when semaglutide (or tirzepatide) may be working "not as much".

For example, dosing semaglutide or tirzepatide once menstruation starts has seemed to be the "least effective" time frame for some people. Benefits like appetite suppression inflammation reduction may seem less pronounced.

Keep notes about injection time/date/amount. Track the exact dates of cycle starting/stopping. Make notes (or at least be aware) about changes in mind & body each week as well.

Doing so may offer some insight - for peace of mind or possibly to make a decision about adjusting the dosing schedule.

 

[Here2Learn]

It seems like the week before, during, and after one's menstruation cycle may be a time frame when semaglutide (or tirzepatide) may be working "not as much".

For example, dosing semaglutide or tirzepatide once menstruation starts has seemed to be the "least effective" time frame for some people. Benefits like appetite suppression inflammation reduction may seem less pronounced.

Keep notes about injection time/date/amount. Track the exact dates of cycle starting/stopping. Make notes (or at least be aware) about changes in mind & body each week as well.

Doing so may offer some insight - for peace of mind or possibly to make a decision about adjusting the dosing schedule.

Little harder for me to track as I had to have a partial hysterectomy. Just a guessing game as to when the cycle is, actually since getting on Sema I’ve started having “period” pain again which is wild.

 

[Here2Learn]

I did take .5mg dose of Reta a couple days after my Sema dose and was wired. I wasn’t having heart palpitations but definitely felt off, almost like a panic attack. Or at least what I think a panic attack would feel like. On the bright side I did have a lot more energy.

 

[RonStutter]

It seems like the week before, during, and after one's menstruation cycle may be a time frame when semaglutide (or tirzepatide) may be working "not as much".

Does that mean that mean there's women that only get maximum effectiveness one week a month?

 

[egruberman]

I think people are perfectly capable of controlling their dietary intake without GLP drugs.

I’m going to try and offer a measured response to this and presume that this was just sloppy use of language.

If by “people are perfectly capable” you mean “some people are reasonably able to control their dietary intake by employing a host of different strategies, a great deal of focus and effort and then only for a short period of time during prep” then sure. I agree.

For those people it’s either their job or their hobby and many will say that during prep, everything else in their life takes a lower priority.

If you meant to apply your statement to the general population then it’s even more absurd, but I presume not. As for this forum, not everyone here is going to step on a stage. I suspect a small fraction of the folks here will. For those that aren’t, titrating appetite to meet their goals is a great tool, especially when that tool seemingly comes with a host of other benefits.

For those that do plan to step on a stage, it’s a trickier proposition, but I suspect still a useful tool for many that do plan to step on a stage, depending on individual genetics. For myself, I don’t plan on competing, but I am bulking presently and keeping in tirzepatide. I don’t have any problems gaining weight and want to grow very slowly. I will also enjoy the benefit of increased insulin sensitivity to offset the GH as well as the other benefits.

 

[Here2Learn]

Just to circle back to my post. I switch to Tirz, doing 2.5mg, has helped some with inflammation with no appetite suppression. I don’t mind not having the suppression as I can control that piece and it will only help me LT imo. Now, I did add .5mg of Reta and feel my inflammation reduction is even better and I do have better energy. Thursday is Tirz, I’m going to bump to 3mg and Tuesdays is Reta. No plans to increase Reta at this time.

 

[GearUnit]

I am on 1.4 weeogy from pharmacy in my country
I switched to 10mg Tirzepatide from qsc Yesterday
It seems alot weaker than weeogy.
But I will report back on this.

 

[Here2Learn]

I am on 1.4 weeogy from pharmacy in my country
I switched to 10mg Tirzepatide from qsc Yesterday
It seems alot weaker than weeogy.
But I will report back on this.

I’ve seen people say the name brand stuff is stronger than the peptide options. Seems to be pretty standard.

 

[GearUnit]

I’ve seen people say the name brand stuff is stronger than the peptide options. Seems to be pretty standard.

I did 20mg in total and I feel zero sides. With is great. Not sure about appetite suppressant it is not that strong. Like to try one of the other glp

 

[Here2Learn]

I did 20mg in total and I feel zero sides. With is great. Not sure about appetite suppressant it is not that strong. Like to try one of the other glp

I’m at 3 mg T and .5mg R so I am no where near being able to speak to 20mg doses. Lol.

 

[egruberman]

I’ve seen people say the name brand stuff is stronger than the peptide options. Seems to be pretty standard.

There is no evidence to that effect. I've personally used pharma and UGL semaglutide with no discernible difference.

 

[Grey Spartan]

Phentermine is like legal speed. I lost 30 lbs from my heart racing 24.7

Funny thing about Phentermine, it did nothing for my appetite but was a cool buz.

My primary doc said I was obese according to the BMI chart. So I told him to give me some sema (my wife wanted it so I figured I could get it for free). He told me to come in and see him. Well he was busy so I saw a female doc, when she walked in she gave a "What the fuck are you doing here look". She said she expected to see a obese guy not me. She actually called me vain. LOL. I told her It isn't me it the doc so to slow her name calling ass down. Anyway, she said no on the sema because they can only give to to diabetics so Phentermine it is. She says I need to get my heart and liver checked because Phentermine kills people. Sema, not one death.

 

[Ghoul]

Tirz is much gentler than Sema, and you really need the full 4 week/4 dose period to reach max blood plasma level to experience the full appetite suppression effects. That said, pharma Tirz didn't have a significant effect for me until 10mg+ doses.