Test/npp/mast ratio suggestions

[Jake1012]

I've decided on sust/npp/mast for my winter bulk and wanted suggestions on dosing ratios. I plan on pinning all 3 eod so I know the dosing will be a little weird so suggestions don't have to be exact just a general Idea. I was thinking something like 450/200/200 but then I've seen a couple people say they had good results doing the same dose across the board like 300/300/300

 

[Aquaman]

For me as I prefer my test lower and the rest higher would be 200 test 300 NPP 300 Mast. Less sides for me that way as less aromatisation.

 

[Str21]

ill do the same compounds this offseason
I was thinking something like:
week1-4 test 300
week5-8 test 300 mast 300 npp 200
week 9-12 test 500 mast 500 npp 300
week 13-16 test 600 mast 600 npp 400

 

[BigTomJ]

ill do the same compounds this offseason
I was thinking something like:
week1-4 test 300
week5-8 test 300 mast 300 npp 200
week 9-12 test 500 mast 500 npp 300
week 13-16 test 600 mast 600 npp 400

Why?

 

[Str21]

Why?

last time I went with 300/300/300 and bump up to 400/400/400.
this time I just want to try test higher, I will bump up the dosages only if needed.

 

[Jake1012]

last time I went with 300/300/300 and bump up to 400/400/400.
this time I just want to try test higher, I will bump up the dosages only if needed.

Why wait the 4 weeks in the beginning to start the other compounds?

 

[BigTomJ]

I

last time I went with 300/300/300 and bump up to 400/400/400.
this time I just want to try test higher, I will bump up the dosages only if needed.

I'm saying why change your protocol 4 times in one cycle.

Pick a dose and go.

 

[Str21]

Why wait the 4 weeks in the beginning to start the other compounds?

To get more gains from upping the test those 4 weeks, add the secondary peds and slowly increase the dosages

 

[Str21]

I

I'm saying why change your protocol 4 times in one cycle.

Pick a dose and go.

To get the maximum from each dosage and increase when I see I need it, so I’ll have less sides until I find my sweet spot.

 

[phenominal34]

To get more gains from upping the test those 4 weeks, add the secondary peds and slowly increase the dosages

You will not get more gains by increasing test 4 weeks lol

 

[Astartes]

To get the maximum from each dosage and increase when I see I need it, so I’ll have less sides until I find my sweet spot.

This isn’t how hormones work. You are using an antiquated thought process we now know to be defunct. AR receptors don’t “fatigue” or become “saturated” requiring titration of doses. Stick with one dosing for your bulk

 

[29trt]

This isn’t how hormones work. You are using an antiquated thought process we now know to be defunct. AR receptors don’t “fatigue” or become “saturated” requiring titration of doses. Stick with one dosing for your bulk

the titrating upwards approach is not used to enhance the anabolic effects of a compound but to ameliorate the side effects.
this is especially wise when using multiple grams of gear, the body needs time to adapt, if you jump from trt straight to 2-3 grams of gear you will definetly get more sides than if you increased the dosages over a span of months.
this might also be linked to the body limited ability to upregulate the AR, if too much androgens are present but no place to attach no bueno.
I have not found any study mentioning the speed at which the AR is increased in relation to androgens.

 

[lilchikin]

For me as I prefer my test lower and the rest higher would be 200 test 300 NPP 300 Mast. Less sides for me that way as less aromatisation.

Yep me too, trt test and let the other compounds go for the ride

 

[Astartes]

the titrating upwards approach is not used to enhance the anabolic effects of a compound but to ameliorate the side effects.
this is especially wise when using multiple grams of gear, the body needs time to adapt, if you jump from trt straight to 2-3 grams of gear you will definetly get more sides than if you increased the dosages over a span of months.
this might also be linked to the body limited ability to upregulate the AR, if too much androgens are present but no place to attach no bueno.
I have not found any study mentioning the speed at which the AR is increased in relation to androgens.

Gotcha. My commentary was more targeted at “typical” dosing at or below a gram. Interesting thought. I can see the theory behind that. Not sure I’m bought in but I certainly can’t rule it out in my mind through simple critical thinking.

I’m curious as to the science (@Type-IIx any insight?) and honestly the anecdotal experience behind it as well. I’ve never been over 1.5 grams so I can’t speak from a personal standpoint.

 

[Type-IIx]

Gotcha. My commentary was more targeted at “typical” dosing at or below a gram. Interesting thought. I can see the theory behind that. Not sure I’m bought in but I certainly can’t rule it out in my mind through simple critical thinking.

I’m curious as to the science (@Type-IIx any insight?) and honestly the anecdotal experience behind it as well. I’ve never been over 1.5 grams so I can’t speak from a personal standpoint.

In principle, I think it's true that titrating from moderately-high to very-high doses both increases the anabolic effect and tolerability (versus jumping straight to very-high doses). Certainly, the androgen/estrogen ratio modulates if not controls a lot of estrogenic effects. It's probable that the pharmacodynamic effects on E2 are more acute than the pharmacokinetic release of esterified androgen, and of course the effects that arise out of nuclear binding (protein synthesis).

 

[Astartes]

In principle, I think it's true that titrating from moderately-high to very-high doses both increases the anabolic effect and tolerability (versus jumping straight to very-high doses). Certainly, the androgen/estrogen ratio modulates if not controls a lot of estrogenic effects. It's probable that the pharmacodynamic effects on E2 are more acute than the pharmacokinetic release of esterified androgen, and of course the effects that arise out of nuclear binding (protein synthesis).

Thank you again brother. Appreciate your insight