There is a problem with liothyronine in general. It's not the most stable compound in the best of circumstances. I suspect it has to do with the aromatic ring of the tyrosine being especially susceptible to light and oxidation, but I really don't know.
Within the same batch of pharma compounds -- the same bottle or same blister pack -- you can get variation in dosing. It's very frustrating.
So, along with compounds being underdosed or adulterated, you've got that to worry about. Though I'm not sure I'd be able to tolerate 100 mg of the real deal anyway... it hits me pretty hard.
