Transdermal: Test Base vs Test-P

[baxter0312]

I made a primo cream but I think it's enanthate and not acetate

Edit: started a thread

 

[Deleted member 59947]

He doesn't actually know anything. But be grateful he figured out to mix dmso and TNE together

You're mad about something ?

 

[Deleted member 59947]

@Goingstronger

What do you know about enanthate ester getting through the skin? Not at all or 10% or what?

Given that's it's heavier by quite a few Daltons than propionate, there is no chance it goes through the dermis.

Skin permeation of testosterone and its ester derivatives in rats - PubMed

To establish the optimum conditions for improving the transdermal delivery of testosterone, we studied the relationship between the lipophilicity of testosterone ester derivatives and the rat skin permeation rate of testosterone. We performed a rat skin permeation study of testosterone and its...

pubmed.ncbi.nlm.nih.gov

 

[baxter0312]

Given that's it's heavier by quite a few Daltons than propionate, there is no chance it goes through the dermis.

Skin permeation of testosterone and its ester derivatives in rats - PubMed

To establish the optimum conditions for improving the transdermal delivery of testosterone, we studied the relationship between the lipophilicity of testosterone ester derivatives and the rat skin permeation rate of testosterone. We performed a rat skin permeation study of testosterone and its...

pubmed.ncbi.nlm.nih.gov

it's far from optimal but how can you say not at all? test enanthate is 400 g/mol which puts it right on the borderline, so you would think at least some gets through.

 

[baxter0312]

The 500 Dalton rule for the skin penetration of chemical compounds and drugs - PubMed

Human skin has unique properties of which functioning as a physicochemical barrier is one of the most apparent. The human integument is able to resist the penetration of many molecules. However, especially smaller molecules can surpass transcutaneously. They are able to go by the corneal layer...

pubmed.ncbi.nlm.nih.gov

 

[baxter0312]

1 dalton = 1 g/mol

Test base 288 g/mol
Test ace 330 g/mol
Test prop 344 g/mol
Test valerate 372 g/mol
Test e 400 g/mol
Test c 412 g/mol

If 500 is the “boundary” between getting through and not getting through and 288 is no ester logic would have it at 400 something would be getting through

 

[baxter0312]

Estradiol valerate is what they use in those patches for menopausal women. So 372 is smooth sailing but 400 is a brick wall???

 

[Deleted member 59947]

it's far from optimal but how can you say not at all? test enanthate is 400 g/mol which puts it right on the borderline, so you would think at least some gets through.

Did you read the study I posted ?

 

[Deleted member 59947]

1 dalton = 1 g/mol

Test base 288 g/mol
Test ace 330 g/mol
Test prop 344 g/mol
Test valerate 372 g/mol
Test e 400 g/mol
Test c 412 g/mol

If 500 is the “boundary” between getting through and not getting through and 288 is no ester logic would have it at 400 something would be getting through

You asked me if it's not getting through at all or if it's going through a little bit ?

Given how you formulated your question, you were ready to get "not at all" as an answer.

Why are you mad now that the answer is "not at all" ?

 

[baxter0312]

Bro nobody here is mad

Get the chip off your shoulder

If you can’t explain yourself further that’s cool,

 

[Deleted member 59947]

Bro nobody here is mad

Get the chip off your shoulder

If you can’t explain yourself further that’s cool,

The study I posted is self-explanatory.

I'm starting to question your comprehension skills.

 

[klokke23]

The study I posted is self-explanatory.

I'm starting to question your comprehension skills.

How about giving a proper answer if you already know the answer? Are you really telling him to read a whole study?

 

[baxter0312]

Regardless of the study I posted things that need Additional explanation not covered in that study . I’m not going to question his comprehension skills I think he’s just being a prick

 

[Deleted member 59947]

How about giving a proper answer if you already know the answer? Are you really telling him to read a whole study?

"Whole study" ?

The conclusions are only a few lines long.

I think you didn't even click on the link.

I gave an answer in plain English and I linked a study to substantiate my claims.

That makes two of you with questionable comprehension skills.

 

[klokke23]

"Whole study" ?

The conclusions are only a few lines long.

I think you didn't even click on the link.

I gave an answer in plain English and I linked a study to substantiate my claims.

That makes two of you with questionable comprehension skills.

No I didn't click the fucking link. You think you're hot shit for reading a study lol

 

[Deleted member 59947]

No I didn't click the fucking link. You think you're hot shit for reading a study lol

@Type-IIx this guy may be a good candidate to substantiate your claim that androgens diminish cognitive capacities, if you ever need a lab rat.

 

[klokke23]

@Type-IIx this guy may be a good candidate to substantiate your claim that androgens diminish cognitive capacities, if you ever need a lab rat.

Lol. Calling for help. Pathetic. Hello @Jin23 check out this asshole huh XDXD

 

[Deleted member 59947]

Lol. Calling for help. Pathetic. Hello @Jin23 check out this asshole huh XDXD

Seems that you are out of arguments. Not a big surprise, but still satisfying to see I was not wrong about you.

 

[klokke23]

Seems that you are out of arguments. Not a big surprise, but still satisfying to see I was not wrong about you.

Bro thinks we're in a rap battle

 

[Slicknyc]

Now you have a shit ton of BB and BA making it to your blood stream, causing black spots in visions, headaches and diarrhea. These are the compounds to be blamed for "test flu", not testosterone itself.

Not even considering it must be costing you a shit ton more than using raws.
You could have bought test prop powder and dissolved it in BA and DMSO for a fraction of the price.

The reason us transdermal researchers have struggled for the past two years to come up with the best solution, is because BA is toxic. Otherwise it's been ages everyone would be making transdermals with BA and dissolving any ester.

Question- why don’t you prefer Phlojel Ulta as carrier? Too bad Salvo by Iron Legion has been discontinued. Have you used boldenone or nandrolone base transdermals? Thoughts?