Unbelievable... IGF-1 is low

[smartgear]

Igf-1 will be low due to

-caloric deficit
-trenbolone
-time / the longer you take exogenous rHGH the more the body adapts and produces antibodies (and the lower Igf-1 will be, to a certain point)
-low estrogen if I remember correctly but not sure so take it as what it's worth

Yes, I'm in caloric deficit right now.

I don't use trenbolone. I'm currently on testosterone and turinabol, but I'm planning to switch to testosterone and anavar soon.

Oral steroids increase liver enzymes. Can this suppress the conversion of HGH into IGF-1 by the liver?

E2 is not low, it's actually elevated - 500 pmol/L.

 

[HB_22]

Yes, I'm in caloric deficit right now.

There is your reason for seeing low igf-1.

 

[smartgear]

There is your reason for seeing low igf-1.

Well, IGF-1 is not really low, it's at the upper side of the reference range, meaning it's high. But I wanted it to be unnaturally high (above the reference range).

So, with 5 IUs HGH a day and caloric surplus, would it go beyond the reference range?

I thought that a supra physiological HGH dose (5 IUs a day) and HGH level (almost 6 ng/mL), would force to body to produce a lot of IGF-1 regardless of the diet. It seems I was wrong.

And what about the e2 level? I said it's 500 pmol/L. In such case, do I need AIs to reduce it assuming high e2 suppresses IGF-1 and makes it bound (unusable)? If it doesn't cause this, I'm not gonna use AIs because I don't have any e2 side effects.

 

[HB_22]

Well, IGF-1 is not really low, it's at the upper side of the reference range, meaning it's high. But I wanted it to be unnaturally high (above the reference range).

It's low for 5IUs, thats what I meant.

So, with 5 IUs HGH a day and caloric surplus, would it go beyond the reference range?

Yes, very likely. But you have to be in a caloric surplus for quite some time. Carbs + hgh will let your Igf-1 rise (to a certain point depending on the amount of hgh).

 

[smartgear]

It's low for 5IUs, thats what I meant.

If my IGF-1 is low for 5 IUs HGH a day, which puts me at 5.88 ng/mL HGH, and doesn't even go above the reference range, doesn't that mean my IGF-1 was near to non-existent when I had a natural HGH level, which was 0.03 ng/dL, and probably never in my life went above 1.00 ng/dL?

The reference range limit HGH is 3.00 ng/dL. If 5.88 ng/dL HGH can't increase IGF-1 above reference range and IGF-1 is actually low for that HGH level, I don't see a reason not to think I have a medical condition that caused me to have abnormally low IGF-1 my whole life, including during puberty.

If IGF-1 is low when HGH is 5.88 ng/mL, then it was non-existent when HGH was 0.03 ng/dL.

 

[songsofpyramids]

If IGF-1 is low when HGH is 5.88 ng/mL, then it was non-existent when HGH was 0.03 ng/dL

Your igf1 isn’t low, and it could be all sorts of personal reasons that are impacting your tests. You’re taking orals, have sky high estro, and in caloric deficit. All these impact conversion to igf1. Try when you’re at maintenance, with e2 in check, and not taking orals.

These tests are snapshots in time, not a holistic investigation. You could have gotten the test at a bad time, or had a bad test itself. You need more than 2 tests to make these conclusions.

 

[Toaster]

If my IGF-1 is low for 5 IUs HGH a day, which puts me at 5.88 ng/mL HGH, and doesn't even go above the reference range, doesn't that mean my IGF-1 was near to non-existent when I had a natural HGH level, which was 0.03 ng/dL, and probably never in my life went above 1.00 ng/dL?

The reference range limit HGH is 3.00 ng/dL. If 5.88 ng/dL HGH can't increase IGF-1 above reference range and IGF-1 is actually low for that HGH level, I don't see a reason not to think I have a medical condition that caused me to have abnormally low IGF-1 my whole life, including during puberty.

If IGF-1 is low when HGH is 5.88 ng/mL, then it was non-existent when HGH was 0.03 ng/dL.

Why do people like this make frantic posts looking for help then argue with people who give them answers?

As for what I quoted. None of what you said means anything because you don't have any data to back it up. You also have no idea how the drugs you're using work.

You may have a medical condition, but it's most likely psychological. This is compounded by the fact that you're trying to use drugs to fix it without an understanding of their effects.

Paranoia + lack of knowledge= this post

 

[jankoch]

-time / the longer you take exogenous rHGH the more the body adapts and produces antibodies (and the lower Igf-1 will be, to a certain point)

do you know any studies showing that?

 

[HB_22]

do you know any studies showing that?

https://www.researchgate.net/publication/8679304_Growth_Hormone_Antibodies_Formation_in_Patients_Treated_with_Recombinant_Human_Growth_Hormone