Hi,
Second post.
I'm currently running Sarms S4, and have posted a summary in another thread, but now want to ask a question regarding Nolvadex and Albuterol.
I had been using my Sarms with some Nolvadex to test the effects, though It was only for a couple of days. I did a Drug Interaction search on drugs.com, and to be using Nolvadex and Alb came up with a Moderate Warning:
tamoxifen ? albuterol
Applies to: Tamoxen (tamoxifen), albuterol
MONITOR: Beta-2 adrenergic agonists can cause dose-related prolongation of the QT interval and potassium loss. Theoretically, coadministration with other agents that can prolong the QT interval may result in additive effects and increased risk of ventricular arrhythmias including torsade de pointes and sudden death. In general, the risk of an individual agent or a combination of agents causing ventricular arrhythmia in association with QT prolongation is largely unpredictable but may be increased by certain underlying risk factors such as congenital long QT syndrome, cardiac disease, and electrolyte disturbances (e.g., hypokalemia, hypomagnesemia). In addition, the extent of drug-induced QT prolongation is dependent on the particular drug(s) involved and dosage(s) of the drug(s). Clinically significant prolongation of QT interval and hypokalemia occur infrequently when beta-2 adrenergic agonists are inhaled at normally recommended dosages. However, these effects may be more common when the drugs are administered systemically or when recommended dosages are exceeded.
MANAGEMENT: Caution is advised if beta-2 adrenergic agonists are used in combination with other drugs that prolong the QT interval, including class IA and III antiarrhythmic agents, certain neuroleptic agents, phenothiazines, tricyclic antidepressants, quinolones, ketolide and macrolide antibiotics, and cisapride. Patients should be advised to seek medical attention if they experience symptoms that could indicate the occurrence of torsades de pointes such as dizziness, palpitations, or syncope.
Given that the active halflife for Nolvadex is 14 days, should I just wait out 14-20 days, and then begin using Albuterol?
Any thoughts?
Thanks.
Second post.
I'm currently running Sarms S4, and have posted a summary in another thread, but now want to ask a question regarding Nolvadex and Albuterol.
I had been using my Sarms with some Nolvadex to test the effects, though It was only for a couple of days. I did a Drug Interaction search on drugs.com, and to be using Nolvadex and Alb came up with a Moderate Warning:
tamoxifen ? albuterol
Applies to: Tamoxen (tamoxifen), albuterol
MONITOR: Beta-2 adrenergic agonists can cause dose-related prolongation of the QT interval and potassium loss. Theoretically, coadministration with other agents that can prolong the QT interval may result in additive effects and increased risk of ventricular arrhythmias including torsade de pointes and sudden death. In general, the risk of an individual agent or a combination of agents causing ventricular arrhythmia in association with QT prolongation is largely unpredictable but may be increased by certain underlying risk factors such as congenital long QT syndrome, cardiac disease, and electrolyte disturbances (e.g., hypokalemia, hypomagnesemia). In addition, the extent of drug-induced QT prolongation is dependent on the particular drug(s) involved and dosage(s) of the drug(s). Clinically significant prolongation of QT interval and hypokalemia occur infrequently when beta-2 adrenergic agonists are inhaled at normally recommended dosages. However, these effects may be more common when the drugs are administered systemically or when recommended dosages are exceeded.
MANAGEMENT: Caution is advised if beta-2 adrenergic agonists are used in combination with other drugs that prolong the QT interval, including class IA and III antiarrhythmic agents, certain neuroleptic agents, phenothiazines, tricyclic antidepressants, quinolones, ketolide and macrolide antibiotics, and cisapride. Patients should be advised to seek medical attention if they experience symptoms that could indicate the occurrence of torsades de pointes such as dizziness, palpitations, or syncope.
Given that the active halflife for Nolvadex is 14 days, should I just wait out 14-20 days, and then begin using Albuterol?
Any thoughts?
Thanks.
