Vitamin D-2 50,000 units and Thyroid connection?..

[Thirstforknowledge]

I was prescribed 50,000 units of Vitamin D-2 (although D-3 is considered more bio-active and comes over the counter) and I was to take it once a week for four weeks and then once a month after.

The first three days on this dose was a little much--very sleeply probably because of the uptake of calcium and magnesium, but after that I felt better than i have felt in years outside of a side effect of minor forgetfulness--but i had a ton of energy and was told Vit D helped regulate both thyroid and Testo.

The problem was after the first four weeks and I had to wait until the monthly dose-- I got VERY tired and in fact some shaky jitterness-anxiety like feeling and was fatigued.

Any thoughts?

 

[zkt]

Weekly And Biweekly Vitamin D2 Prevents Vitamin D Deficiency

Perhaps the efffects you describe are due to the psyche influencing the soma.

 

[Michael Scally MD]

What is your Vit. D level?

 

[amar7]

Ergocalciferol is effective, some studies compare it IU to IU, as a weak argument to prove its inefficacy. Prof. Holick, the best Vitamin D expert I came across, says Ergocalciferol aka Vitamin D2 is equally effective and it is beneficial for vegans and people who suffer a chronic kidney disease

 

[amar7]

[ame=http://www.youtube.com/watch?v=okucyte2HCE]Michael F. Holick, Ph.D., M.D. discusses THE VITAMIN D SOLUTION - YouTube[/ame]

 

[amar7]

Are the side effect you have, after you changed to the monthly intake? This may be due to the half life, you could try to split it into 4 doses a week?

I wonder if D2 is also fat soluble and how it gets converted in the body. Can you explain how this works, DrScally?

edit: Vitamin D2 lowers TSH, while colecalciferol seems to increase it
source: Ergocalciferol and Cholecalciferol Can Both Correct 25-Hydroxyvitamin D Deficiency - Renal and Urology News
maybe stacking ergo- and colecalciferol is synergistic in getting the right serum levels of 2,5 OH-D and 1,25 OH-D plus a stable TSH?

 

[Thirstforknowledge]

Weekly And Biweekly Vitamin D2 Prevents Vitamin D Deficiency

Perhaps the efffects you describe are due to the psyche influencing the soma.

Nope--I don't think so, Vitamin D acts like a hormone in the body and can affect both the thyroid and testosterone.

 

[Thirstforknowledge]

what is your vit. D level?

19-l (30-100)

 

[Thirstforknowledge]

Are the side effect you have, after you changed to the monthly intake? This may be due to the half life, you could try to split it into 4 doses a week?

I wonder if D2 is also fat soluble and how it gets converted in the body. Can you explain how this works, DrScally?

edit: Vitamin D2 lowers TSH, while colecalciferol seems to increase it
source: Ergocalciferol and Cholecalciferol Can Both Correct 25-Hydroxyvitamin D Deficiency - Renal and Urology News
maybe stacking ergo- and colecalciferol is synergistic in getting the right serum levels of 2,5 OH-D and 1,25 OH-D plus a stable TSH?

The only problem is is that the D-2 comes in a small gel cap at 50,000 units. Can't split that, so i asked the Doctor to go with 50,000IU's every 2-weeks instead of once every 4-weeks to see if it has an effect.

I am thinking the original sleepiness was because of the up take of calcium and magnesium---
I am also thinking that the anxiety later could have been not from the Vitamin D-2 itself, but either from switching from once a week for weeks to once a month and changing hormone regulation (remember Vitamin D acts like a hormone in the body) ---OR----using up my available calcium and magnesium at a higher rate than normal---especially since I don't drink milk or have a of foods that contain this in my diet=Depletion?

Calcium and magnesium are important for anxiety prevention. I am wondering what other nutrients or pathology would be affects by high dose Vitamin D-2?

I also think the reason this would happen less often with D-3 is because of the lower, over of the counter doses.

Any thoughts?

 

[hardasnails1973]

Biotics research emulsified forte only thing that helped me and many other people i have recommend it to

 

[LW64]

19-l (30-100)

That's low.

Is that after D2 supplementation?

 

[zkt]

Nope--I don't think so, Vitamin D acts like a hormone in the body and can affect both the thyroid and testosterone.

Yep, just fishin

 

[Thirstforknowledge]

That's low.

Is that after D2 supplementation?

Before.

 

[Thirstforknowledge]

Yep, just fishin

So do people need to supplement with either calcium, magnesium or both when taking Vitamin D-2?

 

[Thirstforknowledge]

Ergocalciferol is effective, some studies compare it IU to IU, as a weak argument to prove its inefficacy. Prof. Holick, the best Vitamin D expert I came across, says Ergocalciferol aka Vitamin D2 is equally effective and it is beneficial for vegans and people who suffer a chronic kidney disease

Are you saying D-2 is better than D-3 if you have chronic kidney disease?

 

[LW64]

So do people need to supplement with either calcium, magnesium or both when taking Vitamin D-2?

Not necessarily, but supping with magnesium is a good idea since it's not likely you're getting very much of it, even if you eat a healthy diet. It's a situation roughly similar to vitamin D. With Vitamin D , we end up deficient because modern lifestyle is mostly indoors. In the case of magnesium, the main dietary source for a long time was water, but now with modern water treament methods and softening, it isnt there any more.

A healthy diet will give you plenty (maybe even too much) of calcium.

I take 50,000 or 60,000 IU/week of D3 and my level is 66. I also take 300 to 450 mg/day magnesium citrate. Magnesium deficiency has been linked to depression, metabolic syndrome, migraines, osteoporosis, kidney stones...it's a rather long list...

 

[Thirstforknowledge]

Not necessarily, but supping with magnesium is a good idea since it's not likely you're getting very much of it, even if you eat a healthy diet. It's a situation roughly similar to vitamin D. With Vitamin D , we end up deficient because modern lifestyle is mostly indoors. In the case of magnesium, the main dietary source for a long time was water, but now with modern water treament methods and softening, it isnt there any more.

A healthy diet will give you plenty (maybe even too much) of calcium.

I take 50,000 or 60,000 IU/week of D3 and my level is 66. I also take 300 to 450 mg/day magnesium citrate. Magnesium deficiency has been linked to depression, metabolic syndrome, migraines, osteoporosis, kidney stones...it's a rather long list...

It's interesting that Vitamin D is also related to and linked to those very issues. In fact the Vitamin D was need for the uptake of Calcium and magnesium.

However based on what you are saying and taking in magnesium, I think I understand why I have had issues and you haven't-----(and also from what people are saying related to a Vitamin D toxicity)---in that many cases it is isn't toxicity at all but magnesium needs to be take with Vitamin D to feel good, something my doctor didn't tell me. At high levels of Vitamin D over time if you don't have decent magnesium levels there will be issues.

I do have a question---- is there a reason you chose magnesium citrate over other forms of magnesium?

 

[LW64]

A chelated form of magnesium is absorbed better. Dont waste your money on magnesium oxide. Vit D also needs vit K and vit A to work properly but, again, if you're eating a healthy diet you should be ingesting enough of them. Eat healthy fats with green, leafy vegetables to help get the fat solubles (A, D, E, and K) and minerals into your body.

Have you seen this site?

Vitamin D Council > Information on Vitamin D, Vitamin D Deficiency and Vitamin D Toxicity

I dont know that taking magnesium will make you 'feel good', but it does have a relaxing effect - it's a natural calcium channel blocker and can lower blood pressure. I take it before I go to sleep.

 

[virtuosa150]

Before supping with vit D, my level was 24. I started biotics research D at varying doses. it was found that my level didn't buge until 20000iu/day. Then I only got to around 50 or so. My doc had me go up to 28000iu. Now I'm a little high at 108.

My doc has me starting 50000 iu prescription 3x/week. The problem with biotics reasearch vit. D is, it's drops that are absorded orally. Now, is that large drops, or small drops? The prescription stuff is a pill form. Takes the guess work out of it. my doctor didn't mention magnesium or calcium supplementation.

 

[Thirstforknowledge]

Before supping with vit D, my level was 24. I started biotics research D at varying doses. it was found that my level didn't buge until 20000iu/day. Then I only got to around 50 or so. My doc had me go up to 28000iu. Now I'm a little high at 108.

My doc has me starting 50000 iu prescription 3x/week. The problem with biotics reasearch vit. D is, it's drops that are absorded orally. Now, is that large drops, or small drops? The prescription stuff is a pill form. Takes the guess work out of it. my doctor didn't mention magnesium or calcium supplementation.

Doc has you on 50,000IU 3x week?

He started me at 50,000IU once a week for 4-weeks (prescription as well) and then once a month, have you noticed any positive or negative effects?

How are you feeling so far?