This is what finally convinced me to lower my LDL cholesterol as low as possible. There seems to be no concern here about actually "needing" LDL cholesterol for any necessary functions. In fact Dr O'Connor has been maintaining an undetectable LDL as in zero. And he's totally fine. Even if there are risks to going too low, the risks of letting ASCVD run wild by using gear and/or having unchecked LDL levels and low HDL levels far outweigh it in my mind but we all need to make that choice for ourselves. I'd also venture to say that many many steroid users who have abused the drugs for any significant length of time have some level of ASCVD beyond their age and most don't know it.
"Study suggests lower LDL cholesterol is better
A recent meta-analysis published in JAMA Cardiology suggests that it is both safe and effective to lower LDL below 70 mg/dL. The authors reviewed a large database of CVD patients with LDL levels averaging 70 mg/dL or less at the start of the studies. On average, there was a 20% drop in CVD risk seen for every 39 mg/dL drop in LDL cholesterol. In other words, a drop in LDL from 70 mg/dL down to 31 mg/dL was associated with 20% fewer CVD events such as heart attack or stroke."
Lowering LDL cholesterol has been shown to lower risk of cardiovascular disease. Recent studies have suggested that more aggressive goals for LDL levels in people who already have CVD can decrease ...
www.health.harvard.edu