Who here is on a statin?

Thanks for sharing.

Now that you mention it, I don't know if they can prescribe pita in my country. But I know they prescribe rosu, which seems superior to simvastatin. I think I'll wait, complain and try to get pita or rosuvastatin prescribed.
Rosuva is satisfactory. Side effect profile isn’t as good as pita but it’s not terrible. It will have robust effect at 5-10 mg
 
Niacin produces poor quality HDL so despite the number rising it’s either going to be useless or even harmful, since “bad” HDL is inflammatory. That’s why all the cardiology guidelines dropped it.

Pita raises HDL quantity AND increases quality. (For anyone curious, APO-I is the marker that indicates HDL quality).

Not sure what supps you’re using to lower cholesterol but I’m going to guess you could buy Pita with the money spent on them and get a better outcome.

Is one of them Red Yeast Rice?
It's not just making bad HDL but one of the terminal metabolites from niacin is known to be inflammatory on its own, so it's a double whammy.

 
I am (again).
I do not see any risk in low/moderate dose statin therapy.

I also think statins should be a staple supplement during cycle/orals.
For one they are tough on your liver and two certain statins will freely attack your muscle as readily as they will your liver.

No magic pills in this world, everything has its cost.
 
For one they are tough on your liver and two certain statins will freely attack your muscle as readily as they will your liver.

No magic pills in this world, everything has its cost.
Saying "there's no such thing as magic pills" and "everything has a cost" is just spouting some platitudes to back up whatever position you've decided you want to take.

Basing your worldview on pithy sayings doesn't make much sense.

As we understand more and more how and why things work, we are able to make better and better drugs. There are quite a few drugs that have effectively no unwanted side effects when taken at therapeutic doses.
 
Finally got back complete results, with Lp(a) finishing them out. Quite a few other results not pertinent to this thread like DHEA, Vitamin D, Prolactin, B12 etc.. all came back good. Which is remarkable in the case of DHEA because I had been chronically low for years. Can't build mass for shit, but I can stop the hell out of those plaques from forming. True genetic potential.

IMG_0367.webp
 
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Little update:
My entire bloodwork attached (all I could find)
I tried to find as much from the past I've had and knocked up all in spreadsheet.

I've had a cholesterol problem since I was a kid.
Few years ago diagnosed with hypercholesterolemia..
My lipids are shite because for few years I was on statins they were giving me were causing my muscles tearing apart literally pain af.

Specially with my low Test levels it wasn't helpful for year because 12 years ago I just stopped roids and never came off of it properly no PCT or anything..

In 2022 they sticked me on Atorvastatin 80mg I was knackered after that.
I stopped taking it and then they lovered it to 40mg and included Ezitimibe 10mg.
I kept Ezitimibe and only started Atorvastatin which ended up the same..Agony.

Now I am on Rosuva 5mg only and I am taking Red yeast rice supplements too.. LDL is going down but HDL is going with it too..
I don't feel as much bad now maybe because I've started my TRT 2 months ago now..(doing TRT myself because NHS not keen on starting it and actually I feel better I do it myself)

I do fish oil and CoQ10 supplements too

I wish somehow I could protect my HDL..
I asked for Pitavastatin but apparently NHS is not allowed Pita in UK..
Also need to keep an eye on my Triglicerides
 

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It looks like RYR in the UK is allowed to contain monacolin k, so this makes more sense than people using it in the US where it is illegal for it to contain it, but monacolin k is chemically identical to lovastatin, the first generation statin that is basically never prescribed anymore because it has one of the worst efficacy to side effect profiles of any statin.

If other statins have given you problems I would be surprised if lovastatin was better - for most people it's among the worst, and you're also effectively doubling up on statin usage.
 
It looks like RYR in the UK is allowed to contain monacolin k, so this makes more sense than people using it in the US where it is illegal for it to contain it, but monacolin k is chemically identical to lovastatin, the first generation statin that is basically never prescribed anymore because it has one of the worst efficacy to side effect profiles of any statin.

If other statins have given you problems I would be surprised if lovastatin was better - for most people it's among the worst, and you're also effectively doubling up on statin usage.
Some red yeast rice supplements also could have citrinin in them, which is a toxin that can harm the kidneys. As you point out, since the active ingredient in RYR is a statin, it doesn't make sense to combine it with a statin anyway.

If you aren't tolerating the statins well, maybe consider an alternative to statin such as bempedoic acid.
 
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