RedSwingline
Member
Again, I appreciate the info. Either way, better to be safe. I don’t have a subscription to sagepub and therefore could not read the whole study but the abstract was telling:I'm sure 20% will have an effect, how quickly who can say. You'd have to analyze the gear to determine what and how much leeched into it.
Obviously the longer the time, the more will migrate into the oil.
The chemical being extracted is polydimethylsiloxane, PDMS.
PDMS isn't particularly toxic orally.
PDMS is mildly toxic subcutaneously, and appears to build up in place, since the body has no means to break it down or flush it out.
PDMS that reaches the circulatory system is toxic and can be fatal in high doses.
The max acceptable limit for injectables is 93ug/day or about 1/10ml / day. That seems like a lot, but I'd rather keep it out entirely.
PDMS with high MW has minimal toxic symptoms with non-detectable degradation/elimination by both intraperitoneal and subcutaneous administration routes, while exposure to either PDMS or small molecule dimethyl silicone compounds by the intravenous administration route may lead to death. We here determined a general parenteral permitted daily exposure (PDE) of 93 μg/day for inorganic silicon element and 100 μg/day for organic silicon element by reviewing toxicological data of both forms of silicon.
