Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[FastBun]

Aggregates form over time. The less time between reconstitution and use the better. Or the less time between filtering and use is better.

Since you're using a vial every 3 days, I'd reconstitute however many vials would fit into a 10ml syringe. Draw them all into the syringe, remove needle and attach filter, reattach needle.

Then backfill an insulin syringe just before you use it. Once you do it a few times it only takes seconds. Then whatever aggregates grow in syringe are filtered out and there's not enough time for new ones to form in the insulin syringe,

If that's too much work, just filter a few vials at a time (draw into syringe, attach filter, inject back into vial) and use however you normally would, or backfill a bunch of insulin syringes in advance from the filtered syringe,

Where is best place and filter you recommend???

 

[MissedArmDay66]

Realizing aggregates must be reforming over time, I moved to the next level, loading a 3ml syringe with the entire vial contents and filtering right into an insulin syringe just before injecting.

Were you able to source a syringe with a stopper that minimizes leaching while the reconned peptide is sitting in it for the duration of time it takes to get through the vial?

 

[mok4315]

Where is best place and filter you recommend???

Sterile 0.2 μm PES Syringe Filters

Hydrophilic PES syringe filters with single or double-layer membrane. Pore sizes of 0.2μm. Diameter of 13mm/25mm/33mm with Luer lock. Sterile individually packed.

shop.cobetter.com

Or these:

(75/Pk) PALL Acrodisc 13mm 0.2um Supor Membrane Syringe Filters 4602 | eBay

Find many great new & used options and get the best deals for (75/Pk) PALL Acrodisc 13mm 0.2um Supor Membrane Syringe Filters 4602 at the best online prices at eBay! Free shipping for many products!

www.ebay.com

Edit to say both for peptides.

 

[throwawaybb21]

How long has this been? and is it a USPS number?

12/31. YunExpress

 

[0x33]

Where is best place and filter you recommend???

I'd suggest this hydrophilic PVDF filter as it has the lowest protein binding Amazon.com

 

[MissedArmDay66]

Where is best place and filter you recommend???

 

[expylon]

Imagine qsc returns under a new name but for security they cant say they are qsc so we think all other new sources are some random ass chinese and we ignore them and they go bankrupt while we are discussing color tops here

 

[Excel.exe]

so we think all other new sources are some random ass chinese

how long do you think tracy will not be able to ask someone to eat shit?

we ignore them and they go bankrupt while we are discussing color tops here

lol

 

[Middus]

12/31. YunExpress

Hmm... Can't help with any info on that especially as Yun suffered a bust stateside.. Maybe just keep hitting multiple trackers to see if any info pops up

 

[hghlover]

They're expected to be back soon?

Also, other experiences with their tirzepatide? Getting swelling at the injection site doesn't sound too nice.

 

[Nested]

I wonder though if he does come back that he will just sell peps and hgh. The margins are better and there's less drama with the authorities.

**** This

 

[SWFL-239]

Aggregates form over time. The less time between reconstitution and use the better. Or the less time between filtering and use is better.

Since you're using a vial every 3 days, I'd reconstitute however many vials would fit into a 10ml syringe. Draw them all into the syringe, remove needle and attach filter, reattach needle.

Then backfill an insulin syringe just before you use it. Once you do it a few times it only takes seconds. Then whatever aggregates grow in syringe are filtered out and there's not enough time for new ones to form in the insulin syringe,

If that's too much work, just filter a few vials at a time (draw into syringe, attach filter, inject back into vial) and use however you normally would, or backfill a bunch of insulin syringes in advance from the filtered syringe,

Right now for the GH I just mix up two vials and backfill it all into pins. I could almost fit a kit into a 10ml. I’m guessing I could do the same with a 3ml for hcg and Tirz. Would there be any problem loading a slin pin with GH, Tirz and hcg if you are immediately using it. How is back loading with the bigger syringes seems like it would be hard to push .2ml accurately or without shooting it all the way to the tip.

 

[dasking]

Hmm... Can't help with any info on that especially as Yun suffered a bust stateside.. Maybe just keep hitting multiple trackers to see if any info pops up

That's what I was about to say if it's a Yun express package I wouldn't hold my breath. Mine was China post and usps claims my package has now left Cali. Praying it is my new years promo and not a seizure letter I'm tracking lmfao.

 

[bigtom343]

Hey is Tracy single?

 

[Ghoul]

Right now for the GH I just mix up two vials and backfill it all into pins. I could almost fit a kit into a 10ml. I’m guessing I could do the same with a 3ml for hcg and Tirz. Would there be any problem loading a slin pin with GH, Tirz and hcg if you are immediately using it. How is back loading with the bigger syringes seems like it would be hard to push .2ml accurately or without shooting it all the way to the tip.

No absolutely do not mix peptides in the same container, syringe or otherwise.

All you are doing is is creating more points for peptides to adhere to each other, forming unique aggregates, effectively creating millions of random new drug molecules, which, at the least will inactivate a certain amount of the peptides and trigger more of an immune reponse.

The FDA has warned about this reckless practice with unknown consequences. There are no pharma drugs that include multiple peptides. The few that have considered combining two, none of which are approved, used polymers to ensure they couldn't stick to each other.

People need to get over the notion that if they inject something and they don't feel anything bad happen within a day it must be fine.

 

[Ghoul]

I'd suggest this hydrophilic PVDF filter as it has the lowest protein binding Amazon.com

View attachment 314243

I know there's sometimes conflicting information out there, but PES is hands down the lowest protein binding membrane in real world applications where minimal loss is a factor and always chosen over PVDF in aqueous protein filtering unless harsh solvents are involved:

 

[narta]

People need to get over the notion that if they inject something and they don't feel anything bad happen within a day it must be fine.

Do we have any measurable data on real life implications from aggregates aka double blind studies?

 

[Ghoul]

Do we have any measurable data on real life implications from aggregates aka double blind studies?

Double blind implies in humans.

So your question is do we have double blind studies in which humans were intentionally injected with protein aggregates, something every organization involved in the development and regulation of pharmaceuticals knows are harmful?

We have plenty of animal studies demonstrating the damage protein aggregates cause.

It's now the main area of focus related to peptide/protein drug safety. Above everything else, from initial development, production, packaging, and onwards, since there are dozens of factors involved that can cause aggregation. (PH, physical stress, temperature, interactions with surfaces like glass or plastic, etc).

 

[narta]

We have plenty of animal studies demonstrating the damage protein aggregates cause.

Do we have any measurable data on animals then? That n subjects were injected with aggregate containing solutions and a non acceptable percentage suffered serious damage and/or developed an immunological adverse response?

In addition is there actual measurable data that gives us a cause and effect correlation between factors that cause aggregates and their end result? P.x. physical stress causes % much aggregates +/-5 Celsius that much etc

 

[SpicyMeatball]

Imagine qsc returns under a new name but for security they cant say they are qsc so we think all other new sources are some random ass chinese and we ignore them and they go bankrupt while we are discussing color tops here

the next chinses source to join meso is is going to be accused of being tracy no matter what