Has anyone managed to damage their kidneys in the absence of high BP?

[explodingHeart]

A better question:

Is gear (mainly testosterone) directly damaging kidneys even if your BP is sub 120/80 throughout most of the day?

Another factor could be overly hard workouts to failure, giving you high CKI and temporarily protein in urine (common with crossfit), or even high protein intakes in general.

I've noticed my cystatin C goes from .65 to .85ish on a blast. Could also be the fact I'm lifting heavier and generating more waste for my kidneys to filter.

Kidney issues are scary. Once you damage them, your life is basically over.

 

[Imip007]

A better question:

Is gear (mainly testosterone) directly damaging kidneys even if your BP is sub 120/80 throughout most of the day?

Another factor could be overly hard workouts to failure, giving you high CKI and temporarily protein in urine (common with crossfit), or even high protein intakes in general.

I've noticed my cystatin C goes from .65 to .85ish on a blast. Could also be the fact I'm lifting heavier and generating more waste for my kidneys to filter.

Kidney issues are scary. Once you damage them, your life is basically over.

kidney can be scary iv recently been going through this issue of protein leaking in urine firstime ever i gave a sample results came in at shocking 1400s range 0 -30 wtf.

They since last 6 months been running all kind of labs to still discover the root of this issue man. Biopsy is next resort but i declind as iv come off all protein supps changed my diet as iv always lived a high protein low carb for years as its works for me.

Now new lifestyle is wtf can i eat having to use carbs & fats and min protein has got my numbers down to 100 - 300 still.
They got me on bp meds low dose losartan to help the issue but that shit has thrown off my alt ast on bloods so now im looking to find natural option even tho my bp hardly goes over 135s /80s.

I may try a plantbased foods/supps which they think is what i need to switch too going forward.

 

[IndividualMan]

Blood Thickness, consistently high Blood sugar (180+), higher stress on the body through strenous workouts, can all damage/ lower Glomerular filtration rate and damage kidneys.
Sepsis is also a big one, that shit is real bad for kidneys. but if you're septic, you have a more pressing issue at hand.

I've noticed my cystatin C goes from .65 to .85ish on a blast. Could also be the fact I'm lifting heavier and generating more waste for my kidneys to filter.

in your case, it probably really is just the heavier lifting+upped dosages temporarily generating more waste

 

[explodingHeart]

im looking to find natural option even tho my bp hardly goes over 135s /80s.

age?

 

[Imip007]

Im 42 bud

 

[lift4lyfe]

A better question:

Is gear (mainly testosterone) directly damaging kidneys even if your BP is sub 120/80 throughout most of the day?

Another factor could be overly hard workouts to failure, giving you high CKI and temporarily protein in urine (common with crossfit), or even high protein intakes in general.

I've noticed my cystatin C goes from .65 to .85ish on a blast. Could also be the fact I'm lifting heavier and generating more waste for my kidneys to filter.

Kidney issues are scary. Once you damage them, your life is basically over.

Yeah... my cysC got very high on a blast with a caloric surplus despite BP never above 130. Creatinine stayed very low. Everything else on blood work was normal. I think it was the high doses of AAS + high protein intake and not drinking enough water. I dropped the AAS dose to half, lowered protein, and drastically increased water intake, and my cysC came back into normal range.

 

[Slowww]

I have a friend who is 30 who has damaged his kidney with his last couple cycles. It’s obvious based on his blood work. His blood pressure is fine though.

 

[Eddie.]

Hello everyone! @explodingHeart sorry for hijacking your thread but I think there’s no need to open a new one.

I’d appreciate some thoughts regarding my situation. I recently tested my cystatin c and it doesn’t look so good. It’s the first time I’m testing it since in my country all labs and suggest only creatinine and urea for kidney function and some labs don’t even test cystatin c.

I’ve never had issues with kidney markers, I was always in range. Creatinine would be from 0,9 to 1,2 with top range 1,4. So my cystatin c came out 1,2 which kinda panicked me but I quickly realised that top of the range in the specific lab is 1,5 so I’m inside the range but still high. Unfortunately I was so dumb this morning that I didn’t even thought to order a e-gfr based on cystatin c. I never payed attention because so far I could only have the egfr based on creatinine which is inaccurate.

Creatinine came out 1,1 and urea 31 with top range 35. My bp is always low, currently at 108/55. I already supplement astragalus root 4gr once a day from nutricost which I’m planning to double.

I’m in a slight deficit with 300gr protein from all sources (including oats, rice etc) and the bloods were taken after 6 weeks on 600 test and 300 primo. I also take 3,5 IU gh and 1,5mg reta.

What I can think of a med that can potentially affect kidneys if taken long term and I’m already taking is nexium , a ppi which I’m taking for 12 years straight (yes, I know) but I’m taking half of the lowest dose (10mg a day).

Obviously I’m not seeking medical advice here, I’m planning to see a nephrologist soon, probably do some ultrasound and further labs, just some thoughts about my situation from anyone that knows a few things. TIA.

 

[IndividualMan]

Getting an appointment with your nephro is a great idea, plus did you get your kidneys checked for Cysts when you were younger/ are kidney cysts a thig in your family? Is you Blood sugar fine ( not continously above 200)?

What I can think of a med that can potentially affect kidneys if taken long term and I’m already taking is nexium , a ppi which I’m taking for 12 years straight (yes, I know) but I’m taking half of the lowest dose (10mg a day).

Regarding Nexium, while if have heard of longterm use, the "long term" part usually refers to a few months at a time at your (10mg) dose.
Seeing as Nexium might fuck with with a few sytems that are kidney adjacent (nr1 non stomach related side effect is excessive swelling in the legs/feet, a water retention issue,) and some rather important minerals (magnesium and potassium), I would bet a large sum of 1-cent-coins (at least 12), that it might have something to do with your mildly elevated kidney markers.

However, if your kidney markers have always been in that range, (0.9-1.2, now at 1.1), and while your CysC is kinda high (assuming that it is steady), there could be other reasons for it to be that way (past sepsis, chemo, past rec drug abuse, etc.)

 

[Sampei]

Hello everyone! @explodingHeart sorry for hijacking your thread but I think there’s no need to open a new one.

I’d appreciate some thoughts regarding my situation. I recently tested my cystatin c and it doesn’t look so good. It’s the first time I’m testing it since in my country all labs and suggest only creatinine and urea for kidney function and some labs don’t even test cystatin c.

I’ve never had issues with kidney markers, I was always in range. Creatinine would be from 0,9 to 1,2 with top range 1,4. So my cystatin c came out 1,2 which kinda panicked me but I quickly realised that top of the range in the specific lab is 1,5 so I’m inside the range but still high. Unfortunately I was so dumb this morning that I didn’t even thought to order a e-gfr based on cystatin c. I never payed attention because so far I could only have the egfr based on creatinine which is inaccurate.

Creatinine came out 1,1 and urea 31 with top range 35. My bp is always low, currently at 108/55. I already supplement astragalus root 4gr once a day from nutricost which I’m planning to double.

I’m in a slight deficit with 300gr protein from all sources (including oats, rice etc) and the bloods were taken after 6 weeks on 600 test and 300 primo. I also take 3,5 IU gh and 1,5mg reta.

What I can think of a med that can potentially affect kidneys if taken long term and I’m already taking is nexium , a ppi which I’m taking for 12 years straight (yes, I know) but I’m taking half of the lowest dose (10mg a day).

Obviously I’m not seeking medical advice here, I’m planning to see a nephrologist soon, probably do some ultrasound and further labs, just some thoughts about my situation from anyone that knows a few things. TIA.

EGFR can be easily calculated by yourself lol no need to get it from the lab. You have creatine, you have cystatin C you just need a calculator that you can find anywhere on the web, just Google it

 

[Eddie.]

Getting an appointment with your nephro is a great idea, plus did you get your kidneys checked for Cysts when you were younger/ are kidney cysts a thig in your family? Is you Blood sugar fine ( not continously above 200)?


Regarding Nexium, while if have heard of longterm use, the "long term" part usually refers to a few months at a time at your (10mg) dose.
Seeing as Nexium might fuck with with a few sytems that are kidney adjacent (nr1 non stomach related side effect is excessive swelling in the legs/feet, a water retention issue,) and some rather important minerals (magnesium and potassium), I would bet a large sum of 1-cent-coins (at least 12), that it might have something to do with your mildly elevated kidney markers.

However, if your kidney markers have always been in that range, (0.9-1.2, now at 1.1), and while your CysC is kinda high (assuming that it is steady), there could be other reasons for it to be that way (past sepsis, chemo, past rec drug abuse, etc.)

No rec use or even smoke, no chemo or other heavy treatments and long term use of drugs. I take sildenafil or tadalafil though (not ed ofc).

Kidney cysts no I don’t recall something from my family. Recently my mother was diagnosed with enlarged adrenals but that’s it regarding kidney issues.

I’ve heard of people being longer on ppis and much bigger dosages,eg 20-40mg of esomeprazole. I’ve made multiple attempts to stop it but withdrawal is horrendous.

Forgot to mention that I have almost a year that I started taking ezetimibe and 2,5mg rosuvostatin twice a week. I know they can elevate liver markers but I have no clue if they can harm kidneys too.

I have more than a year I checked serum minerals, everything was in check, calcium, magnesium, sodium, potassium though was borderline low. Also d3 and b12 were good.

Apparently I’ve never experienced water retention or edema, either from high estrogens or feasting on salty foods, or while I was taking 100mg anadrol, when I introduced hgh etc.

Also, another thing I forgot to mention is that my piss is kinda on the yellow side despite I’m drinking at least a gallon of water. It’s on the clear side half of the times I pee and the rest is going yellowish. Well, first couple times in the morning is due to b complex and multivitamin though.

Thanks for taking the time man, appreciate it.

Edit: my blood glucose I’ve no idea how much is it between meals but my fasting is between 80-100 and my A1c is 4,9 to 5,2 for the latest year at least.

EGFR can be easily calculated by yourself lol no need to get it from the lab. You have creatine, you have cystatin C you just need a calculator that you can find anywhere on the web, just Google it

Hey thanks man, I didn’t know it. I’ve found a calculator and it shows the egfr from both combined at 76 but tbh I don’t think it’s accurate. I believe it takes the usual cystatin c range which tops at 1,2 and not my lab’s assay which has a range of 0,3 to 1,5. I’ll try to find a different lab and test again cystatin c with egfr this time.

 

[Sampei]

No rec use or even smoke, no chemo or other heavy treatments and long term use of drugs. I take sildenafil or tadalafil though (not ed ofc).

Kidney cysts no I don’t recall something from my family. Recently my mother was diagnosed with enlarged adrenals but that’s it regarding kidney issues.

I’ve heard of people being longer on ppis and much bigger dosages,eg 20-40mg of esomeprazole. I’ve made multiple attempts to stop it but withdrawal is horrendous.

Forgot to mention that I have almost a year that I started taking ezetimibe and 2,5mg rosuvostatin twice a week. I know they can elevate liver markers but I have no clue if they can harm kidneys too.

I have more than a year I checked serum minerals, everything was in check, calcium, magnesium, sodium, potassium though was borderline low. Also d3 and b12 were good.

Apparently I’ve never experienced water retention or edema, either from high estrogens or feasting on salty foods, or while I was taking 100mg anadrol, when I introduced hgh etc.

Also, another thing I forgot to mention is that my piss is kinda on the yellow side despite I’m drinking at least a gallon of water. It’s on the clear side half of the times I pee and the rest is going yellowish. Well, first couple times in the morning is due to b complex and multivitamin though.

Thanks for taking the time man, appreciate it.

Edit: my blood glucose I’ve no idea how much is it between meals but my fasting is between 80-100 and my A1c is 4,9 to 5,2 for the latest year at least.



Hey thanks man, I didn’t know it. I’ve found a calculator and it shows the egfr from both combined at 76 but tbh I don’t think it’s accurate. I believe it takes the usual cystatin c range which tops at 1,2 and not my lab’s assay which has a range of 0,3 to 1,5. I’ll try to find a different lab and test again cystatin c with egfr this time.

You need to use a proper one that correct for area.

eGFR Calculator

www.kidney.org

Use this one. The lab range means nothing

 

[CorgisOnTren]

No rec use or even smoke, no chemo or other heavy treatments and long term use of drugs. I take sildenafil or tadalafil though (not ed ofc).

Kidney cysts no I don’t recall something from my family. Recently my mother was diagnosed with enlarged adrenals but that’s it regarding kidney issues.

I’ve heard of people being longer on ppis and much bigger dosages,eg 20-40mg of esomeprazole. I’ve made multiple attempts to stop it but withdrawal is horrendous.

Forgot to mention that I have almost a year that I started taking ezetimibe and 2,5mg rosuvostatin twice a week. I know they can elevate liver markers but I have no clue if they can harm kidneys too.

I have more than a year I checked serum minerals, everything was in check, calcium, magnesium, sodium, potassium though was borderline low. Also d3 and b12 were good.

Apparently I’ve never experienced water retention or edema, either from high estrogens or feasting on salty foods, or while I was taking 100mg anadrol, when I introduced hgh etc.

Also, another thing I forgot to mention is that my piss is kinda on the yellow side despite I’m drinking at least a gallon of water. It’s on the clear side half of the times I pee and the rest is going yellowish. Well, first couple times in the morning is due to b complex and multivitamin though.

Thanks for taking the time man, appreciate it.

Edit: my blood glucose I’ve no idea how much is it between meals but my fasting is between 80-100 and my A1c is 4,9 to 5,2 for the latest year at least.



Hey thanks man, I didn’t know it. I’ve found a calculator and it shows the egfr from both combined at 76 but tbh I don’t think it’s accurate. I believe it takes the usual cystatin c range which tops at 1,2 and not my lab’s assay which has a range of 0,3 to 1,5. I’ll try to find a different lab and test again cystatin c with egfr this time.

Increase your fluid intake. You’re likely short at a gallon if large and active.

 

[explodingHeart]

Hello everyone! @explodingHeart sorry for hijacking your thread but I think there’s no need to open a new one.

I’d appreciate some thoughts regarding my situation. I recently tested my cystatin c and it doesn’t look so good. It’s the first time I’m testing it since in my country all labs and suggest only creatinine and urea for kidney function and some labs don’t even test cystatin c.

I’ve never had issues with kidney markers, I was always in range. Creatinine would be from 0,9 to 1,2 with top range 1,4. So my cystatin c came out 1,2 which kinda panicked me but I quickly realised that top of the range in the specific lab is 1,5 so I’m inside the range but still high. Unfortunately I was so dumb this morning that I didn’t even thought to order a e-gfr based on cystatin c. I never payed attention because so far I could only have the egfr based on creatinine which is inaccurate.

Creatinine came out 1,1 and urea 31 with top range 35. My bp is always low, currently at 108/55. I already supplement astragalus root 4gr once a day from nutricost which I’m planning to double.

I’m in a slight deficit with 300gr protein from all sources (including oats, rice etc) and the bloods were taken after 6 weeks on 600 test and 300 primo. I also take 3,5 IU gh and 1,5mg reta.

What I can think of a med that can potentially affect kidneys if taken long term and I’m already taking is nexium , a ppi which I’m taking for 12 years straight (yes, I know) but I’m taking half of the lowest dose (10mg a day).

Obviously I’m not seeking medical advice here, I’m planning to see a nephrologist soon, probably do some ultrasound and further labs, just some thoughts about my situation from anyone that knows a few things. TIA.

I actually had you in mind when I made this thread. I hope things get better for you, brother.

Your situation scares the shit out of me, that my benign 250mg to 500mg test is killing my kidneys, although I would assume injectable test is fairly harmless without high bp.

 

[Eddie.]

Increase your fluid intake. You’re likely short at a gallon if large and active.

Yeah, actually a gallon is not usual, most days I’m at 4,5 - 5 liters plus other fluids from coffees, energy drinks, Diet Coke etc. Currently not so active I’m doing a desk job but yeah, it makes sense.. I’ll increase water and drop 20-30gr of protein to help with the waste.

I actually had you in mind when I made this thread. I hope things get better for you, brother.

Your situation scares the shit out of me, that my benign 250mg to 500mg test is killing my kidneys, although I would assume injectable test is fairly harmless without high bp.

Thanks man, really appreciate it! Honestly kidneys is the only organ I’d rather not to mess with but hey, life is full of surprises.

You need to use a proper one that correct for area.

eGFR Calculator

www.kidney.org

Use this one. The lab range means nothing

Thanks man! That showed better results when I added height and weight.

 

[xrayphoton13]

kidney can be scary iv recently been going through this issue of protein leaking in urine firstime ever i gave a sample results came in at shocking 1400s range 0 -30 wtf.

They since last 6 months been running all kind of labs to still discover the root of this issue man. Biopsy is next resort but i declind as iv come off all protein supps changed my diet as iv always lived a high protein low carb for years as its works for me.

Now new lifestyle is wtf can i eat having to use carbs & fats and min protein has got my numbers down to 100 - 300 still.
They got me on bp meds low dose losartan to help the issue but that shit has thrown off my alt ast on bloods so now im looking to find natural option even tho my bp hardly goes over 135s /80s.

I may try a plantbased foods/supps which they think is what i need to switch too going forward.

Magnesium acts as a calcium channel blocker which is a tie of blood pressure lowering medication. Eat foods high in magnesium and supplement with mag glycinate if needed too. Vitamin E is supposedly nature's aspirin but I haven't had as much luck with that one yet. Magnesium and beet root powder (contains nitrates I think) really get my bp down

 

[juicebro]

Something to keep in mind is when you use GH it may give you false kidney readings for both creatinine and cystatin c... Making it look like your kidneys are working better than they actually are. @Eddie.

Anyway, I've said it before in other threads but I'll say it again. I'm a believer in astragulus root extract. My cystatin C just keeps dropping slowly every time i test it. Two years ago average was 0.93 few weeks ago it was 0.69. This is while being on multiple grams+tren the whole time.

 

[Eddie.]

Something to keep in mind is when you use GH it may give you false kidney readings for both creatinine and cystatin c... Making it look like your kidneys are working better than they actually are. @Eddie.

Anyway, I've said it before in other threads but I'll say it again. I'm a believer in astragulus root extract. My cystatin C just keeps dropping slowly every time i test it. Two years ago average was 0.93 few weeks ago it was 0.69. This is while being on multiple grams+tren the whole time.

I’ve never heard of this and can’t say anything about cystatin c since it is the first time that I’m testing it but as far as creatinine, HGH hasn’t affected mine at all. It was always between 0.9 to 1,1.

Also I’m taking already 4gr astragalus for months now and at least my creatinine levels remained the same. As of 3 days ago I raised it to 8gr.

 

[CorgisOnTren]

Something to keep in mind is when you use GH it may give you false kidney readings for both creatinine and cystatin c... Making it look like your kidneys are working better than they actually are. @Eddie.

Anyway, I've said it before in other threads but I'll say it again. I'm a believer in astragulus root extract. My cystatin C just keeps dropping slowly every time i test it. Two years ago average was 0.93 few weeks ago it was 0.69. This is while being on multiple grams+tren the whole time.

I’m 99% sure this is not accurate

 

[juicebro]

I’m 99% sure this is not accurate

View: https://www.youtube.com/watch?v=ZgIuoOfKTJM

HGH increases renal plasma flow and glomerular filtration rate, which might temporarily make kidneys look like they're filtering more efficiently.

But looks like it actually falsely raises Cystatin C at the same time which is interesting....