Steroid Profile Equipoise

I did test and boldenone cyp for a while and even though my e2 was about 20 in bloods I had spicy nipples and possible exacerbation of gyno. After a while of ruling everything out and identifying it was the boldenone likely ramping e1 up despite lowering/controlling e2, i tried a bit of aromasin which helped, and then i went back to test/ primo (still with a little bold) and the issue completely cleared up with e2 still in the 20's.
I’m having the same issue minus the boldenone. I’ve been running 600mg test E, 4mg Retatrutide and my estradiol,ultra sensitive came back 21. Crazy flares and tissue build up in my nipples plus back acne. 1mg Arimidex did nothing for me (maybe bunk). Switched to 12.5mg aromasin and finding some relief.
 
I’m having the same issue minus the boldenone. I’ve been running 600mg test E, 4mg Retatrutide and my estradiol,ultra sensitive came back 21. Crazy flares and tissue build up in my nipples plus back acne. 1mg Arimidex did nothing for me (maybe bunk). Switched to 12.5mg aromasin and finding some relief.
I had similar experience, I wonder if masteron as a SERM would be enough gyro relief.
 
I’m having the same issue minus the boldenone. I’ve been running 600mg test E, 4mg Retatrutide and my estradiol,ultra sensitive came back 21. Crazy flares and tissue build up in my nipples plus back acne. 1mg Arimidex did nothing for me (maybe bunk). Switched to 12.5mg aromasin and finding some relief.
I’m beginning to think wherever Quest sends their E2 Ultrasensitive labs to doesn’t know what they are doing. My June 30th E2 came back at 295. lol. I was only on 150mg Test C at the time. 12-15% BF and I don’t aromatize much at all. I felt great for 295. August first my E2 was 22 through LabCorp.
 
I’m beginning to think wherever Quest sends their E2 Ultrasensitive labs to doesn’t know what they are doing. My June 30th E2 came back at 295. lol. I was only on 150mg Test C at the time. 12-15% BF and I don’t aromatize much at all. I felt great for 295. August first my E2 was 22 through LabCorp.
That’s nuts. I was considering the same thing when I got my results back quest is exactly who I got bloods with on August 1st. They switched our tests. I’m going to go with labcorp next.
 

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You want to check your E1 as well. There is a conversation to E1 that happens at different rates in different people. That is why some people get high e2 and some get low with EQ. Type ii has a really good article on EQ. It has been a huge help while I have been trying to work out EQ.
What week into your EQ cycle would you typically get your first bloodwork?
 
Equipoise does not directly reduce DHT. Neither does Masteron. They indirectly reduce DHT proportionate with the degree to which they suppress the endogenous or natural production of testosterone.

Equipoise is only weakly potentiated by the 5α-reductase and much less so than testosterone. Masteron is not converted to DHT at all.

The net result of an Equipoise+Masteron stack is lower DHT levels.

However, this is only true if you don't include any other AAS that are converted to DHT.
 
The only thing is that boldenone converts to e1 not e2 which is more active and potent. This I think limits its abilities because you have to run high doses for good anabolic effects so its ability to stack is limited. On the other hand, it has good strength gains and equal or superior connective tissue positive effects to deca and low water retention. I probably wont use it anymore because I did get anxiety effects from it and i used bold cyp which im pretty sure is fake sometimes and the undec ester is too long imo. It does have a mild effect as a AI. I am a low aromatizer and my levels were at a all time low with bold and have never been that low again with other compounds. I do not use AIs. Besides I really love nandrolone now because it made me feel euphoric at times and super horny. And it does convert to a form of e2 which is great because I aromatize low and benifit from the extra e2 kick. I did really like how bold didnt cause a ton of hypertrophy because i dont train hypertrophy much.
Nandrolone does not convert to e2.
 
Nandrolone does not convert to e2.

That's what I'm experiencing too. Although i haven't pushed dosages high but 150-200 NPP doesn't raise e2 at all when added in my test/EQ stack.

They say if you run it solo you'll end up with zero estradiol because it's not converting but when you take test and add nandrolone it speeds up e2 conversion but that's not what I've seen.

I think those who deal with gyno issues is due to prolactin, like tren but in lesser degree instead of e2 but maybe I'm wrong.
 
I keep reading in places that boldenone aromatizes to estrone, which I don’t think is true. Only androstenedione (and prohormone precursors) will aromatize to E1.

However, estrone is both a precursor to and metabolite of estradiol via 17β-HSD1/2. So maybe boldenone and perhaps some metabolites/derivatives (including DHB & primobolan) induce or inhibit these enzymes affecting E1/E2 balance?

This would be sort of a similar case to nandrolone, which barely aromatizes but either upregulates expression of aromatase and/or sensitizes the ER to trans activation by estrogen - that’s why adding it to a cycle so commonly results in gyno or ED despite producing nearly extra estrogen on its own.

@Type-IIx any thoughts on this?
 
lol I just listened to that earlier tonight

I’m still thinking this λ1-testosterone group is altering E1/E2 ratio by interfering with the 17β-HSD enzymes. Same goes with primo.
 
Don’t. It starts reducing estrogen conversion from the first week. If you frontload it say goodbye to your estrogens haha. There’s really no need, just pin it and forget about it. Eventually it will peak and do its job while keeping your e2 in check. I hope you’re planning at least a 14+ week run with it.
So if one was to run EQ and wants to be on top of the E2, would you suggest run blood work every two weeks to stay on top of E2 “Asking for a friend” :)
 
So if one was to run EQ and wants to be on top of the E2, would you suggest run blood work every two weeks to stay on top of E2 “Asking for a friend” :)

I'd say to him, If it's the first time you'll gonna run EQ and you don't know much (if at all) suppresses your e2 I'd start with 2/1 test/eq and check e2 at 4 weeks later. It will start working immediately but it would be best to give it some time. If you don't aromatise much you could start with 5/2 test/EQ and adjust later, it's up to you. This time i started with 2/1 like before but e2 was too low after 4 weeks and i raised test. It's trial and error.
 
I'd say to him, If it's the first time you'll gonna run EQ and you don't know much (if at all) suppresses your e2 I'd start with 2/1 test/eq and check e2 at 4 weeks later. It will start working immediately but it would be best to give it some time. If you don't aromatise much you could start with 5/2 test/EQ and adjust later, it's up to you. This time i started with 2/1 like before but e2 was too low after 4 weeks and i raised test. It's trial and error.

Do you think doing bloodwork every two weeks is over kill? If EQ is fast acting on the E2 I want to be able to catch it right way and adjust from there.
 
Do you think doing bloodwork every two weeks is over kill? If EQ is fast acting on the E2 I want to be able to catch it right way and adjust from there.

Yes it’s overkill but if that brings you peace of mind then why not? Around 4-6 weeks it has to be stabilised and not change after this. No need to get obsession over e2.

Derek said 2 IU GH will cause acromegaly.

Irrelevant, this has nothing to do with the facts he presents on that video.
 

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