Accutane permanent cure?

[brutalbuilt]

I know the dry UGl tabs work to a degree but Accutane is supposed to be suspended in oil within gel capsules for a reason. This is not a drug I want to play guessing games with, the consequences are too serious.

I ordered some really cheap legit pharma grade capsules from India. They're available as 5,10,20,30, and 40mg capsules.

As my back and shoulder acne isn't constant and "severe", while the official calculator says I need 12,000mg total. as 50-90mg a day doses to fully shrink the sebaceous glands for a permanent one time cure, I'm going to be more conservative.

I ordered 100 10mg gelcaps and 200 20mg from a pharmacy (that was $175 delivered for reference).

I'll start with 10mg twice a day. Split dose reduces sides. After a month I'll titrate to 20mg AM and 10mg PM for a month. If all is well 20mg twice a day for 2 more months.

That's 3,750mg of total exposure and below the low range of the suggested daily dose which should avoid all short term side effects.

Hopefully that will dry me out just enough to alleviate my very oily "gear skin" and crazy earwax production, while avoiding the short and long term sides of a hardcore full treatment cycle of 12.000mg.

After a 2 month break I'll reassess and can repeat if needed. It seems shrinking those sebaceous glands is a one way street, and since I doubt I need to shut them down entirely just reduce their activity, I'm happy to take the slow, incremental route.

i see... i just wanna run a low dose 10-20mg cycle for a couple months and see how well it works

im gonna go to the dermatologist to get a script cause i dont trust ugl accutane, ive learned from a very knowledgeable person making accutane is a really difficult process and requires really high end expensive equipment that a lot of these ugl's cant afford or have the knowledge to use

 

[Ghoul]

a little off topic but i am experincing so back acne. i scrub with 10% benzol solution 2x a day. and i have been taking 100mg of doxycycine a day for about 30 days. its not horrible but still not completly going away. should i riase my dose of doxy??

Max dose is 200mg a day, but needs to be split, preferably 10 hours apart. Up to 3 months at that dose. Wear sunscreen, your skin will damage easily at 200mg.

 

[PopeyeTheSailerDude]

I've read one or two 6 month courses of Accutane can permanently cure acne in a lot of cases.

Has this worked permanently for anyone with steroid induced acne?

I suspect a permanent cure isn't for the steroid induced type, but I'd like to know if it's worth a try given the nasty sides or just stick to Doxycycline, which is effective and no sides but temporary.

accutane isn’t even a permanent fix for non steroid users. I think my doctor said it has maybe a 60/70% chance. And when using gear you’re messing with the hormones again so it’s less likely to be a permanent fix.
I’ve been prescribed it twice in my life by doctors, one before I ever touched gear and once after doing 500 test per week. I haven’t touched gear for a few years since and I still get the odd spot pop up, I’m mid 30s now.

Acctutane is the holy grail for bad acne but it comes at such a cost. Make it your last resort especially if it’s summer time!

 

[Ghoul]

accutane isn’t even a permanent fix for non steroid users. I think my doctor said it has maybe a 60/70% chance. And when using gear you’re messing with the hormones again so it’s less likely to be a permanent fix.
I’ve been prescribed it twice in my life by doctors, one before I ever touched gear and once after doing 500 test per week. I haven’t touched gear for a few years since and I still get the odd spot pop up, I’m mid 30s now.

Acctutane is the holy grail for bad acne but it comes at such a cost. Make it your last resort especially if it’s summer time!

Well a 70% success rate as a permanent cure isn't terrible, lol. From what I've read most failures are suspected to be a lack of absorption, since a lot of people don't religiously take each dose with a high fat meal. It makes a huge difference. However, the newest nano-particle versions don't require a meal at all for proper absorbtion, and there's an India pharma generic version of this drug that usually cost $21,000 for a full course! It's less than $150 for the same amount of Sotret NF, the generic of Absorica LD.

 

[ThinBulk]

Accutane is definitely by FAR the strongest acne tool I've heard of. I took it for a few months around 2010. Direct shipped India pharmacy brown gel caps. 20mg up to 40mg and back down to 20mg. It can damage your liver and cause depression. I have a normally great outlook and stopped early because I started to feel the beginnings of depression. I imagine it would crush someone that's already depressed. At 40mg my skin went from greasy to feeling like the desert. Buy good chapstick early. I don't know of a reason to use more than 40mg.

My on cycle acne afterwards was much better than off cycle before using accutane. It's worn off a little over the years, but it's a game changer for people with bad acne. Benzoyl peroxide, antibiotics, etc are all much less effective and temporary. Accutane will absolutely last for years after stopping.

 

[Ghoul]

Accutane is definitely by FAR the strongest acne tool I've heard of. I took it for a few months around 2010. Direct shipped India pharmacy brown gel caps. 20mg up to 40mg and back down to 20mg. It can damage your liver and cause depression. I have a normally great outlook and stopped early because I started to feel the beginnings of depression. I imagine it would crush someone that's already depressed. At 40mg my skin went from greasy to feeling like the desert. Buy good chapstick early. I don't know of a reason to use more than 40mg.

My on cycle acne afterwards was much better than off cycle before using accutane. It's worn off a little over the years, but it's a game changer for people with bad acne. Benzoyl peroxide, antibiotics, etc are all much less effective and temporary. Accutane will absolutely last for years after stopping.

It's definately not for casual use, you have to have a plan. Doses above 10mg should be split twice a day.

At 20mg I have no sides except dry lips. Feel completely fine, lipids in check. Staying on for 4-5 months as that often results in no recurrence of acne for life. Fixed my overactive earwax production as well!

 

[Ateam2023]

a little off topic but i am experincing so back acne. i scrub with 10% benzol solution 2x a day. and i have been taking 100mg of doxycycine a day for about 30 days. its not horrible but still not completly going away. should i riase my dose of doxy??

With my experience doxycycline wasn't the best , i was even taking 200 mg of it daily, my acne was hormonal due to high e and it just didn't budge, I switched to a clyndamiacin 1%ointment from dermatologist and got my estrogen in check and it seems to be finally fading away after 3 months

 

[Ghoul]

With my experience doxycycline wasn't the best , i was even taking 200 mg of it daily, my acne was hormonal due to high e and it just didn't budge, I switched to a clyndamiacin 1%ointment from dermatologist and got my estrogen in check and it seems to be finally fading away after 3 months

Also used Doxy and topicals and antibacterial washes but it always comes back. You get a 10% over or underdosed batch of test and the hormonal shift is enough to bring it back.

I'll be very glad to get rid of it for good.

Hell, there's a debate right now among dermatologists that for mild acne Accutane might be the better first line treatment than antibiotics.

(if you do ever switch DO NOT take Doxy while on Accutane. Tetracyclene antibiotics are the single most dangerous interaction, and can cause brain swelling.). I gave it 4 days to wash out before starting.

 

[Dirthand]

Yeah tried the doxy for about 12 weeks then started clyndamiacin and bactrim it was getting worse so I just said screw it and started acutane about 18 days ago.. 20mg morning 40mg evening. Might do 40 and 40 for about 10 days then 20 and 20.. wekl see how it goes

 

[Ghoul]

Yeah tried the doxy for about 12 weeks then started clyndamiacin and bactrim it was getting worse so I just said screw it and started acutane about 18 days ago.. 20mg morning 40mg evening. Might do 40 and 40 for about 10 days then 20 and 20.. wekl see how it goes

Consistency and time seem to be bigger factors than dose. Whatever dose you can handle for four months will yield at least some good, lasting results, if not an outright cure.

 

[PopeyeTheSailerDude]

It's definately not for casual use, you have to have a plan. Doses above 10mg should be split twice a day.

At 20mg I have no sides except dry lips. Feel completely fine, lipids in check. Staying on for 4-5 months as that often results in no recurrence of acne for life. Fixed my overactive earwax production as well!

20mg was the starting dose for me both times, and up to 60/70. Didn’t have to split dose but have to take with food. But that’s why the doctors make you take blood test before you up the dose to make sure you’re doing ok both physically and mentally. It’s a very harsh drug, worse than the gear people take In most cases. I would never self prescribe myself accutane even though I know the steps, it’s very easy to get if your in a bad way both on nhs and private.

 

[Ghoul]

20mg was the starting dose for me both times, and up to 60/70. Didn’t have to split dose but have to take with food. But that’s why the doctors make you take blood test before you up the dose to make sure you’re doing ok both physically and mentally. It’s a very harsh drug, worse than the gear people take In most cases. I would never self prescribe myself accutane even though I know the steps, it’s very easy to get if your in a bad way both on nhs and private.

The thinking around this has radically changed in the last decade. Low dose treatment protocols have made pre treatment and ongoing blood tests largely unnecessary.

10-20mg doses are almost universally side effect free.

Whoever had you taking 70mg in one shot a day didn't do you any favors, boosting side effects and lowering efficacy, given it's half life it should have been split up.

The collagen regeneration effects have dermatologists prescribing very low dose isotretinoin off label, 10mg once or twice a week, for general skin health improvement and to reverse photoaging.

 

[youwhat?]

Yeah tried the doxy for about 12 weeks then started clyndamiacin and bactrim it was getting worse so I just said screw it and started acutane about 18 days ago.. 20mg morning 40mg evening. Might do 40 and 40 for about 10 days then 20 and 20.. wekl see how it goes

Any results in those 18 days? I’m about 6 days in. My bacne is about 5-10% better I’d say.

 

[Dirthand]

Any results in those 18 days? I’m about 6 days in. My bacne is about 5-10% better I’d say.

Some areas are a little better but still getting a few spots pop uo.. mine wasn't just horribly bad to begin with but I was getting a bunch of blackheads and some swollen white heads . I mean bkackhead on the shoulders are better.

 

[Ghoul]

I didn't have a severe "purge", but about a month in a bunch of small pimples appeared where I never had any before, then disappeared after a weak.

Despite its name, nothing actually "purges", Accutane causes cells in pore lining to change and become less susceptible to acne formation. During the transition, they temporarily become more vulnerable to acne bacteria.

 

[youwhat?]

Some areas are a little better but still getting a few spots pop uo.. mine wasn't just horribly bad to begin with but I was getting a bunch of blackheads and some swollen white heads . I mean bkackhead on the shoulders are better. View attachment 287011

Looks pretty clear to me. My back looked like I had the chicken pox before I started. Never had this issue before, but as soon as I introduced tren h at 300mg a week boom. Bacne.

 

[BOSSBIG]

I did a full 6 month brutal course about 15 years ago. Definitely permanent results but I still get acne breakouts if estrogen gets too high.

 

[Ghoul]

I did a full 6 month brutal course about 15 years ago. Definitely permanent results but I still get acne breakouts if estrogen gets too high.

Accutane was reserved for the most severe cases back then, as you know. Treatment for. moderate acne has only been recently considered acceptable. One big issue with the original was it was impossible to determine the total dose absorbed, so you and another patient on the same treatment could easily vary by 30% by the end.

Sounds like it saved you from the genetic acne curse, mostly. I wonder if another low dose short course would get you over the hump to acne immunity.

I'm definitely coming to the conclusion the nano-particle versions are the only way to go, since the dose absorbed is 100% certain.

 

[Ateam2023]

so as of now, there isn't any sources for said " nano accutane"?

 

[Ghoul]

so as of now, there isn't any sources for said " nano accutane"?

PCT.Zone has Sotret NF 8mg, 16mg, 32mg. Which is equivalent to 10,20,40 of regular Accutane.

I haven't heard from PCT24 yet but his prices tend to be a little sharper so would be worth asking. Especially if you're planning a full course, and getting the 10mg dose for flexibility, you'd want 500 gelcaps+ on hand. (you may end up taking 20mg twice a day and still be "low dose" so 4 gelcaps). That's cheap with Accufine, like $100. I have yet to see the Sotret NF pricing, but in India, it's only about 85¢ more per 10 gelcap strip. so shouldn't be more than another $50 for a 500 gelcap supply.