Certainly, we can say that the 350 mg trenbolone acetate "beginner" dose is extremely high.
Human equivalent dosing from a Synovex implant that delivers 200 mg trenbolone acetate + 20 mg estradiol & has a duration of activity between 80 - 90 days equates to ≈ 0.078 mg/kg weekly, or 7.8 mg tren ace for 100 kg man.
Moreover, bovid are less AR-dense than humans in skeletal muscle, meaning that all else being equal they require a higher dose than humans for equivalent anabolism.
Of course, there are considerable differences in metabolism between man and bovid that might cause orders of magnitude discrepancies in net anabolism.
Bioluminescence data that quantifies the relative potency to transactivate the AR that suggests that 350 mg/w trenbolone is ≈ to 1.5 g/w testosterone.
Finally, we have human evidence, unfortunately with a high risk of bias, in the form of self-reports from professional bodybuilders who competed during the early 1980s to 1997 and used Negma's Parabolan. These professionals report using one or two 1.5 mL ampoules containing 76 mg of trenbolone hexahydrobenzylcarbonate (equivalent to 50 mg trenbolone base) weekly for phenomenal changes to physique.
After reasoning through all these considerations, we can say confidently that 350 mg weekly trenbolone acetate is stupidly high for a 180 lb man on his third cycle.
