Grey Spartan
Member
OK, thanks. Looks like I will be ordering from PCT for the first time.
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OK, thanks. Looks like I will be ordering from PCT for the first time.
I dont think you read the full paper, it clearly shows a reduction in igf1. In this paper there are 2 studies, Study I: dose finding and Study II: PK study .These guys were put in huge doses, 25 and 50mg daily, and saw no impact to IGF.
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males
Abstract. Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestaneacademic.oup.com
I am glad started out very cautiously though, as only 12.5mg/wk was enough. It takes a long while to recover from too high a dose of this AI.
I dont think you read the full paper, it clearly shows a reduction in igf1. In this paper there are 2 studies, Study I: dose finding and Study II: PK study .
The PK study give them one dose of 25 mg only and this did not decrease igf1, the study 1 in what they give for 10 days shows a decrease in igf1View attachment 303441
By the way, I noticed this too. If the test is above 250, then aromasin doesn't seem to help.I prefer aromasin when cruising but on cruise doses of test (220mg/Wk) aromasin for me is stronger than Adex. 25mg 2x a week put my e2 at 15 where 1mg Adex 2x a week puts me at 35.
However on blast doses of test Asin loses it's potency and I need to use Adex to control my e2. I'm sure it's highly individual. I tend to aromatize a lot even though I'm lean and when using mast I aromatize like crazy, assuming it's from crushed shbg