Bulking on GLP1 agonists

MingDao

Member
I've seen multiple posts on bulking with GLP1 agonists, which on paper makes a lot of sense due to nutrient partitioning and better insulin sensitivty. I understand that for high responders bulking on these may be very hard, but I only have mild appetite supression and no nausea from either Sema or Tirz. Fairly confident I can be in a caloric surplus, especially with liquid carbs and extra fat.
Would be very interested in bulking experiences on AAS and GLP1. Did it meaningfully change the ratio of fat v muscle gain?
 
Recent data suggests that injecting GLPs and doing nothing else generally yields better health outcomes. In that sense it is a bit of a cheat. Using anabolics without training and nutrition on the other hand generally does not.

From the perspective of this crowd, someone that has a shitty diet and doesn't exercise that goes from being obese to skinnyfat wouldn't constitute success, but they still may be healthier as a result.

Bringing things back around to OP's question, I ran a bulk on tirz earlier in the year. It was a bit unpleasant as a result of the delayed gastric emptying, but I was able to titrate my appetite to keep the weight gain in check. Without a GLP agonist in the mix and eating a relatively clean diet, my appetite tends to cause me to gain weight pretty steadily.

I'm about to start another bulk and will likely do the same.
I am hoping for leaner bulk (higher muscle/fat ratio gain) on GLP1 vs no GLP1 bulk. How did it go for you?
Gastric emptying delay is non-issue for me, very mild if any. Appetite suppression is also minimal if any, but sema/tirz kind of kill carb cravings for me, which otherwise are rather pronounced on a deficit.
With sema I had to ramp it up to 1mg for it do do anything, tirz seems to work at 2.5mg dose. On either main side effect is loose and more frequent stools and being more gassy. Still tollerable, though.
 
Last edited:
How did it go for you?

I came off entirely a few weeks prior to beginning my cycle, ballooned up in the first 4 weeks and restarted tirz at a low dose. From there I was able to get in enough carbs to have good performance in the gym and gain weight slowly. Ultimately putting on something like 10lbs of lean tissue, maybe…. I don’t totally trust the dexa scan I did after, but progress was mad which is more than I can say for the prior decade.

Also, as a former fatass, this was the first time in my life I tried to gain weight. I was afraid of getting fat again, so I took it easy. Given the amount of lean muscle tissue I have presently I think I just don’t need that much food to grow relative to the bigger guys.

Also, as a former fatass it’s weird to refer to other people as “bigger guys”.

At a low dose I get mild appetite suppression and delayed gastric emptying. Much of my protein comes from whey, which I tolerate well. I also take care not to finish eating as early as possible with my last meal of the day being quite small.
 
Not my logic, my facts.

The only thing I'm coping with is the profound ignorance of GLP haters.


I love glp-1s. Have completely changed my life. I started with prescription Mounjaro and lost over 120 lbs. 1mg a week of semaglutide will give me great blood glucose but won't slow down my digestion at least that I can notice anymore. And I get heart health benefits and everything else glp-1s offer. Given the price of Chinese semaglutide I think it's the better choice over metformin or berberine provided you don't get debilitating sides. I used to get sides a year and a half ago when I started this journey but I no longer do. I've also drastically upped my salad and green veggie intake so that may be helping with my gut flow too
 
then you must not be tracking and weighing your food

The point is to use a GLP1 RA to titrate appetite to achieve the desired amount of growth which obviates the need to track and weigh my food. I have so many other obligations on my time, particularly around meals, that preclude me from being able to do that.

Some can kill an entire pizza & more.

“Some” sure. I don’t personally have cheat days of any sort. I don’t eat fast food, or drink calories outside of whey protein. My family eats out typically once a week or less.

My diet is clean. Nonetheless, if my appetite were unconstrained, I’d gain fat. I’m not suggesting this is some kind of magic workaround to CICO, but rather the product of having been in a deficit for much of the past 18 years. I suspect my NEAT is pretty low much of the time and that nutrient partitioning is off.

I’m not saying I can’t control it or that I need GLP1 RAs to do so, but it’s the best tool I’ve tried so far.
 
Top