Different strokes for different folks. I've tried and could not stand cramps from clen, even just 50 mcg per day. Once cramps were so bad I couldn't walk more than 10 steps without stopping and stretching in pain, even at night in bed I was feeling cramps through my ribs at every twist or turn from a morning dose. In contrast 300 mg of dnp daily makes me feel much more comfortable and the results are much better too.