Can touching a barbell in the gym get you sick with the coronavirus?

[DrinkFlintWater]

(CNN) Three months after President Donald Trump suggested ingesting disinfectants as a treatment for coronavirus, a Florida man and his three sons are facing criminal charges for allegedly selling a toxic solution to tens of thousands of people as a cure for Covid-19.

Mark Grenon, 62, and his sons, Jonathan, 34, Joseph, 32, and Jordan, 26, all of Bradenton, Florida, supposedly manufactured, promoted, and sold "Miracle Mineral Solution" (MMS), a chemical solution containing sodium chlorite and water, the criminal complaint affidavit says.

The men sold the toxic bleach under the guise of Genesis II Church of Health and Healing, an entity they allegedly created in an attempt to avoid government regulation, the US Attorney's Office for the Southern District of Florida said in a statement.

They've been charged with criminal contempt, conspiracy to defraud the United States and conspiracy to violate the Federal Food, Drug, and Cosmetic Act for their alleged actions, the US Attorney's Office said.

CNN hasn't been able to reach the Grenons or their lawyers for comment.

This is actually typical behavior for Florida.

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

Stay Home ...

 

[Michael Scally MD]

It's a COVID World

It's a world of laughter
A world of tears
It's a world of hopes
And a world of fears
There's so much that we share
That it's time we're aware
It's a COVID world after all

It's a COVID world after all
It's a COVID world after all
It's a COVID world after all
It's a COVID, COVID world

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

It's a COVID World

It's a world of laughter
A world of tears
It's a world of hopes
And a world of fears
There's so much that we share
That it's time we're aware
It's a COVID world after all

It's a COVID world after all
It's a COVID world after all
It's a COVID world after all
It's a COVID, COVID world

 

[Michael Scally MD]

“Schools—not restaurants or gyms—turned out to be the country’s worst mega-infectors.”

JERUSALEM—Like beachgoers informed there is no danger just before a tsunami hits, Israelis are stunned by the magnitude of the dramatic turn in their fortune. In under six weeks, they’ve gone from model nation fighting the novel coronavirus to a small, isolated country whose citizens face a long, deadly summer locked down.

On May 17, Israel reported only 10 new cases of COVID-19 in the entire country. It looked like Israel had succeeded in subduing the coronavirus crisis with a lockdown enforced early and strictly, reemerging on the other side with only 271 dead.

Announcing the imminent reopening of restaurants and pubs, Israeli Prime Minister Benjamin Netanyahu, who usually sticks to a formal manner, beamed and told Israelis to “go out and enjoy yourselves.”

Jump to July, when cases of COVID-19 are spiking, putting Israel high on the list of countries who’ve lost control of the virus’ contagion; the economy is cratering, with unemployment at about 23 percent, and the new government is on the verge of collapse.

What happened?

If you ask Siegal Sadetzki, the head of the nation’s public-health service, who served as an Israeli Dr. Anthony Fauci for the past six months and quit her job on Tuesday, the government “has lost its compass.”

Tuesday was Israel’s worst day of contagion, with 1,400 new cases of COVID-19 announced, a record since the start of the outbreak.
Event spaces, bars, and gyms have been re-shut but instructions regarding public transportation remain unclear, and the transport and finance ministers squabble on the airwaves.

On Tuesday, in testimony to the Israeli parliament, Udi Kliner, Sadetzki’s deputy, reported that schools—not restaurants or gyms—turned out to be the country’s worst mega-infectors.

 

[Michael Scally MD]

 

[Michael Scally MD]

Molecular Mechanisms of Sex Bias Differences in COVID-19 Mortality

More men than women have died from COVID-19. Genes encoded on X chromosomes, and sex hormones may explain the decreased fatality of COVID-19 in women.

The angiotensin-converting enzyme 2 gene is located on X chromosomes. Men, with a single X chromosome, may lack the alternative mechanism for cellular protection after exposure to SARS-CoV-2.

Some Toll-like receptors encoded on the X chromosomes can sense SARS-CoV-2 nucleic acids, leading to a stronger innate immunity response in women.

Both estrogen and estrogen receptor-α contribute to T cell activation. Interventional approaches including estrogen-related compounds and androgen receptor antagonists may be considered in patients with COVID-19.

Li Y, Jerkic M, Slutsky AS, Zhang H. Molecular mechanisms of sex bias differences in COVID-19 mortality. Crit Care. 2020;24(1):405. Published 2020 Jul 9. doi:10.1186/s13054-020-03118-8 https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03118-8

 

[Michael Scally MD]

[OA] SARS-CoV-2 and Male Infertility: Possible Multifaceted Pathology

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease 2019 (COVID-19) has been declared a pandemic by the World Health Organization (WHO) on 11th March 2020.

Bulk of research on this virus are carried out to unveil its multivariate pathology. Surprisingly, men are reportedly more vulnerable to COVID-19 even with higher fatality rate compared to women.

Thus, it is crucial to determine whether SARS-CoV-2 infection can even affect male fertility as an immediate or long-term consequence of the disease.

Among the discrete data available, an important finding is that angiotensin converting enzymes 2 (ACE2) receptor, that aids the SARS-CoV-2 entry into host cells, is profoundly expressed in testicular cells.

In addition, the endogenous androgen milieu and its receptors are associated with ACE2 activation reflecting that enhanced testosterone levels may trigger the pathogenesis of COVID-19. In contrary, hypogonadism has also been reported in the acute phase of some COVID-19 cases.

Moreover, SARS-CoV-2 infection-induced uncontrolled inflammatory responses may lead to systemic oxidative stress (OS), whose severe disruptive effects on testicular functions are well-documented.

This article aims to precisely present the possible impact of COVID-19 on male reproductive functions, and to highlight the speculations that need in-depth research for the exact underlying mechanisms how COVID-19 is associated with men's health and fertility.

Dutta S, Sengupta P. SARS-CoV-2 and Male Infertility: Possible Multifaceted Pathology [published online ahead of print, 2020 Jul 10]. Reprod Sci. 2020;10.1007/s43032-020-00261-z. doi:10.1007/s43032-020-00261-z SARS-CoV-2 and Male Infertility: Possible Multifaceted Pathology

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]

 

[Michael Scally MD]