Canadians talk domestic

I've used accutane a lot during my youth. It really depends on the dose you take. I'm even taking it again now to clear my face / neck from my last cycle because I'm simply prone to get it.

I take 10mg right now and will run it for another 2 weeks, which would be 2 months and a half in total. My skin is clear and I've got only the dry (barely) lips as sides. The higher the dose, the more sides will manifest themselves.

Good to know, thanks bro
 
Isotretinoin has been used to treat severe inflammatory acne that is resistant to antibiotics or topical agents; however, it also may cause alterations in lipids and liver enzymes. In this retrospective study, we evaluated changes in lipids and liver enzymes in 322 acne patients who had been treated with oral isotretinoin at our institution over a 3-year period. Each patient’s medical records were evaluated to determine baseline triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels compared to levels recorded at 3 and 6 months following initiation of treatment with oral isotretinoin. Overall, statistically significant increases in TG and LDL levels were noted following treatment with isotretinoin (P<.001 and P<.001, respectively), while HDL levels were shown to decrease (P<.001). Statistically significant increases in AST levels also were noted (P=.016). Although ALT levels also increased, the changes were not statistically significant increases in AST levels also were noted (P=.016). Although ALT levels also increased, the changes were not statistically significant (P=.72). In our study, isotretinoin appeared to have a greater effect on lipids than liver enzymes. Dermatologists should not avoid isotretinoin use for appropriate indications, but close follow-up is important.
 
Accutane wreaks havok on your liver. Take as absolute small amount as possible for the results that you need, treat it like an AAS oral in that respect. It'll probably dry your skin out a bit too. Specially in the canadian cold.

Yea I heard about the negative affect on the liver. I'm monitored by my doc at least and get blood tests regularly but unfortunately my back is a damn mess so the effective dosage may have to be on the higher end. But I'm gonna run it when I'm off everything else so atleast my liver won't be attacked by multiple drugs lol.
 
Yea I heard about the negative affect on the liver. I'm monitored by my doc at least and get blood tests regularly but unfortunately my back is a damn mess so the effective dosage may have to be on the higher end. But I'm gonna run it when I'm off everything else so atleast my liver won't be attacked by multiple drugs lol.

Yea man get those tests regularly.
My brother and I both took accutane in our teens. Both were required to have regular testing to watch liver function. I was okay but my brother was forced to stop due to liver issues that showed up on his testing. He was only a few months in.
 
I wonder how many people freaked out thinking LE had taken over and cleaned everything out of their houses in anticipation of a knock on the door. lol
lol. Any idea why they were down? Maintenance? Or some dickheads did some hacker shit and took down the server?
 
Yea man get those tests regularly.
My brother and I both took accutane in our teens. Both were required to have regular testing to watch liver function. I was okay but my brother was forced to stop due to liver issues that showed up on his testing. He was only a few months in.

Oh shit, thats hardcore. Yea definitely gonna keep on top of it, thanks man!
 
lol. Any idea why they were down? Maintenance? Or some dickheads did some hacker shit and took down the server?

Upgrades I believe, more to come is my understanding. There is a posting from Millard in General Discussion talking about the down time.
 
Hey fellas looking for some input and opinions.

When running your cycles where do you generally keep your estrogen levels?

Off cycle my estrogen level is 56 pmol/L

and,

on 500 mg's of test my estrogen was 256 pmol/L (with 12.5 mg EOD of Aromasin).

Do you believe in keeping your estrogen levels in the normal range or do you keep estrogen high as long as you don't experience symptoms?
 
Hey fellas anyone feel free to comment but I know 3ml is well versed in gh etc so I'd like to get your opinion on mk677 more specifically timing of when to take it. Read too many conflicting info on it and my assumption is its best to take few hrs before bed so you can sleep off any lethargy you may get? Also I know earlier you said keep your bg in check and it can combat this.
 
Hey fellas anyone feel free to comment but I know 3ml is well versed in gh etc so I'd like to get your opinion on mk677 more specifically timing of when to take it. Read too many conflicting info on it and my assumption is its best to take few hrs before bed so you can sleep off any lethargy you may get? Also I know earlier you said keep your bg in check and it can combat this.
My turn for the dumb question, what's bg? Just ordered some mk677, kind wondering the same, time to take it

Thanks
 
Blood Glucose, get a BG monitor at any drug store. They are typically free when you buy the strips.
Got it, like the diabetics tests, I'm planning to run 12.5mg Ed before dl bed time, even at this dosage should I test my bg or not biggie at lower dosage?
 
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