Enclo protocol

[Testocyp]

What’s the best enclomiphene citrate protocol for TRT, cruise and cycle? I’ve read it has a half life of 10 hours, for a dosage of 12.5mg. It acts as an anti-estrogen in the brain, especially in the pituitary, by this mechanism it prevent endogenous shutdown and increase LH/FSH, however I’ve read it can be bad to block estrogen in the brain 24/7, because we need estrogen too.

To prevent side effects of blocked estrogen in the brain, I’ve seen a protocol taking 12.5mg enclo E3D. However, since it has a half life of only 10 hours, wouldn’t it be optimal to use it ED for less shutdown? If taken before bed it will be active during night and morning (which might be optimal with the circadian rythm in mind, since it secrete LH most in the early morning), and out of the system during the day.

Might be a good idea to include some exemestane too, since it can increase LH/FSH and increase IGF-1 which enclo seem to lower.

What do you think about this cruise protocol?
Testo C 250mg EW
Enclo 12.5mg ED before bed
Exemestane 6.25mg E3D or EOD

 

[Testocyp]

Did some more research and seem like enclomiphene usually don’t raise LH/FSH much on bloodwork while on TRT, but people that did use it on TRT experience less athrophy, so maybe it does something afterall. I believe that in order to make enclo effectively prevent shutdown on TRT, and raise LH/FSH, it should be combined with a short acting ester.

A TRT protocol like this might work?

Monday 12.5mg enclo + 6.25mg exemestane

Tuesday 12.5mg enclo + 6.25mg exemestane

Wednesday 25mg enclo + 12.5mg exemestane

Thursday 100mg Test P 12.5mg exemestane

Friday

Saturday 6.25mg exemestane

Sunday

 

[Klimmzugernie]

You want to take clomiphene to prevent your hpta axis shut down while taking testosterone?

 

[Alistair7]

I don’t see any reason to take more than 12.5mg daily. That is a lot of exemestane for just a TRT dose of test.

 

[Alistair7]

What’s with the once a week dose of test P? Did you mean to type CYP?

 

[OmL]

Well, this thread is scary.

 

[Testocyp]

You want to take clomiphene to prevent your hpta axis shut down while taking testosterone?

Basically, yes.

 

[Testocyp]

I don’t see any reason to take more than 12.5mg daily. That is a lot of exemestane for just a TRT dose of test.

The idea behind exemestane is to help enclomiphene improve endogenous production, and prevent HPTA shutdown.

 

[Testocyp]

What’s with the once a week dose of test P? Did you mean to type CYP?

No I mean propionate. With cypionate the testosterone levels will stay elevated, shutting down the HPTA the whole week and thus preventing enclo from doing its job.

I’ve read that propionate has a half life of about 3 days. So in my protocol only 25% of the 100mg injection should be left at wednesday. Such small amount shouldn’t be too suppressive for enclo and exemestane to overcome, so if endogenous production is maintained there won’t be any highs and lows, only highs.

 

[Klimmzugernie]

Your protocol is bullshit.

Do you want to be fertile during TRT?
Or is it just to maintain the size of your testicles? Then add HCG.

 

[Testocyp]

Your protocol is bullshit.

Do you want to be fertile during TRT?
Or is it just to maintain the size of your testicles? Then add HCG.

Might be so. I want to keep both fertility and size. I know HCG + Test C is a safer bet (maybe combined with HMG to ensure fertility), the pros with Test P + enclo protocol is that it require fewer injections and will restore the HPTA (endogenous production of LH/FSH, not only bypass it with HCG/HMG). The cons is that it will give less steady T levels than Test C and it might not work to restore HPTA to 100%.

My idea is basically that, hopefully, there would be plenty of low-T time to keep the HPTA going, with enclo, as long as serum testosterone isn't excessive in the post-injection interval. If this work, testosterone levels will never be hypogonadal low, endogenous T + 50-25mg of propionate will still be present. I realize the exemestane dosage in my protocol is excessive though and have to be reduced.

 

[Alistair7]

OP you should speak to your doctor about Natesto. It’s testosterone delivered through the nose that is supposed to prevent shut down. I have no experience with it but this test P protocol you have outlined is stupid.

Alternatively, test cyp plus HCG is the way to go if it were me. I don’t think enclomiphene is something anyone would want to use long term.

 

[Testocyp]

OP you should speak to your doctor about Natesto. It’s testosterone delivered through the nose that is supposed to prevent shut down. I have no experience with it but this test P protocol you have outlined is stupid.

Alternatively, test cyp plus HCG is the way to go if it were me. I don’t think enclomiphene is something anyone would want to use long term.

Thank you for your advice. I’ve thought about Natesto as an option, however I won’t be able to get Natesto. Making my own Natesto might be an option though, using testosterone base for injection.