I believe this is one of those individual things as far as how people react to it and what you may experience.
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@MisterSuperGod I had a horrible spike in BP (while on script BP meds) and also a bad acid reflux issue at 100mg (I'm also on prescribed Pantoprazole). I simply can't go over 50mg ed without running into trouble, unfortunately.
Train.However, I know two fellas that have ran 100mg with no problems and overall positive experiences.
That being said, there's only one way to find out - go for it and see if it works for you.
Just guessing here due to my own chronic digestive issues but I would say anyone with a history of gastro problems would have trouble with most orals, especially at such high dosages.