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This guy has been using optis from the start... Good enough for him good enough for me.
I just ran out of optis mysef recently and had a few kits of catcafe GH left. I did not notice any difference switching. QSC GH tested better than both of them though so idk if I want to keep paying 40 eur extra per kit just for pretty opti boxes. Probably giving qsc a go next.
If water weight is your only concerns there are cheaper ways to deal with it like diuretics or aldosterone antagonists.
I haven't used pharma consistently to compare but my take is generics most definitely work. I don't know what's wrong with people like chaseirons who didn't get anything out of them but I've made a huge change. Side effects are no longer an issue.