Giant Semaglutide Thread (and other GLP-1 / GIP agonists)

[Doodle]

Wanted to create a thread where everyone can post their experiences with different sourced Semaglutide.

Who are you using?
Pharma vs non?
Dosage?
How long have you been taking it?
What are your thoughts?
Have you lost weight?
Side effects?
Oral vs injection?
Tests?

 

[Ghoul]

Thank you for chiming, I was hoping you would. Much info I have got at this point was from you and I didn't want to depart from practices you shown drug company's recommended.

These compounds are by far the fastest, most effective weight loss drugs ever developed. They only require a small amount of patience as the body adjusts to a higher level of GLP, but it does, and by following the pharma protocol you're nearly guaranteed to be successful at getting to your ideal weight, and with a maintainance dose, staying there for a lifetime.

Right now, her digestive system is going from 100 to 30 miles per hour in an instant, so the side effects are potent. Everything else in her metabolic system needs a little time to catch up and reregulate, but it will. Future increases in dose will cause some mild effects, temporarily, but it'll never be as bad as it is now. Once she gets to her goal weight, she'll feel nothing. People in the long term studies take the same (maintainance) dose for years, and overwhelmingly don't experience any side effects.

That's the "promised land" she'll eventually reach. For most, it's around 6 months.

In a sense she's lucky to be such a good responder. Many, especially males, feel no effect until reaching 7.5mg or higher and don't lose as high of a percentage rate of overall weight. Thats a combination of males having more receptors requiring activation to regulate to a lower weight, and the person to person variation in GLP insufficiency and need more of the hormone to get to the ideal level.

Beyond all of this, GLPs are "putting money in the bank" for better long term health. Almost all organs show evidence of direct beneficial effects from GLP receptor activation. Systemic inflammation is reduced. It protects against the development. of everything from arthritis to alzheimer's and heart disease. The nervous system in particular seems to gain significantly, protecting against the ravages of oxidation and general degradation, preserving vision and cognition.

 

[benfrankparkway]

These compounds are by far the fastest, most effective weight loss drugs ever developed. They only require a small amount of patience as the body adjusts to a higher level of GLP, but it does, and by following the pharma protocol you're nearly guaranteed to be successful at getting to your ideal weight, and with a maintainance dose, staying there for a lifetime.

Right now, her digestive system is going from 100 to 30 miles per hour in an instant, so the side effects are potent. Everything else in her metabolic system needs a little time to catch up and reregulate, but it will. Future increases in dose will cause some mild effects, temporarily, but it'll never be as bad as it is now. Once she gets to her goal weight, she'll feel nothing. People in the long term studies take the same (maintainance) dose for years, and overwhelmingly don't experience any side effects.

That's the "promised land" she'll eventually reach. For most, it's around 6 months.

In a sense she's lucky to be such a good responder. Many, especially males, feel no effect until reaching 7.5mg or higher and don't lose as high of a percentage rate of overall weight. Thats a combination of males having more receptors requiring activation to regulate to a lower weight, and the person to person variation in GLP insufficiency and need more of the hormone to get to the ideal level.

Beyond all of this, GLPs are "putting money in the bank" for better long term health. Almost all organs show evidence of direct beneficial effects from GLP receptor activation. Systemic inflammation is reduced. It protects against the development. of everything from arthritis to alzheimer's and heart disease. The nervous system in particular seems to gain significantly, protecting against the ravages of oxidation and general degradation, preserving vision and cognition.

Sounds good and I will provide this as encouragement as I pass it along to here. In the meantime I have read of some things that could perhaps help, ginger chews, alka seltzer, and I believe I can get some anti nausea medication from a family member who is pregnant.

 

[Ghoul]

Sounds good and I will provide this as encouragement as I pass it along to here. In the meantime I have read of some things that could perhaps help, ginger chews, alka seltzer, and I believe I can get some anti nausea medication from a family member who is pregnant.

Whatever you do, don't start messing with the dose or timing.

And Metamucil. That'll help with the worst of the effects more than anything, in my opinion. It'll take a few days to start working, but for most who've tried it, they stick with that even if they stop taking GLPs. It's just natural fiber from the psyllium flower, but what it does for you in the bathroom is amazing. It corrects constipation and the opposite, making things much more pleasant while digestion is in turmoil.

 

[Avies48]

Sounds good and I will provide this as encouragement as I pass it along to here. In the meantime I have read of some things that could perhaps help, ginger chews, alka seltzer, and I believe I can get some anti nausea medication from a family member who is pregnant.

So there are pct sources where u can buy the anti nausea meds zofran : Ondansetron is what the scientific name is…

Also….

I respond well to meds and a lot of times i
cannnoottt take the starting dosage regardless of what the docs state the starting dosage should be… everyone is different… im trying to to talk my wife into starting lower than the recommended 2.5 mlg per week…. Because when she is dehydrated and has nausea… its bad to the point of non stop puking…, so i hope she takes this into account… it took how many years to pack on the weight yet everyone wants it magically gone in a few months? Sure… for some… and for others?? It could take longer… and if under the official dosage… may take a bit longer but shouldnt pose any real issues…imo

 

[Anat]

Can someone please clarify something about bac water? I’m using Pfizer. If I open a new vial and dilute my 20mg Tirz, which lasts me a month, can I still use the same bac water after that month? All online sources say it’s not recommended to use it after 28 days, but isn’t that more for hospitals where contamination risks are higher? Do you guys keep using it until the 30ml is finished? Thanks!

 

[Ghoul]

Can someone please clarify something about bac water? I’m using Pfizer. If I open a new vial and dilute my 20mg Tirz, which lasts me a month, can I still use the same bac water after that month? All online sources say it’s not recommended to use it after 28 days, but isn’t that more for hospitals where contamination risks are higher? Do you guys keep using it until the 30ml is finished? Thanks!

Provided you use sterile practices, wiping the stopper with an alcohol swab before use, and only going in with a clean needle (not back and forth to the peptide vial) it's fine to use until it's empty.

28 days is the FDA advised limit for all multi-dose vials, but really doesn't apply to BAC.

 

[Anat]

Provided you use sterile practices, wiping the stopper with an alcohol swab before use, and only going in with a clean needle (not back and forth to the peptide vial) it's fine to use until it's empty.

28 days is the FDA advised limit for all multi-dose vials, but really doesn't apply to BAC.

Thanks a lot! I always stick to sterile practices - fresh needles, alcohol swabs, and no cross-contamination. I really appreciate the explanation - it clears up my doubts completely!

 

[Ghoul]

Thanks a lot! I always stick to sterile practices - fresh needles, alcohol swabs, and no cross-contamination. I really appreciate the explanation - it clears up my doubts completely!

As it's extremely pure water and benzyl alcohol, there's nothing to spoil and bacterial growth is impossible within this environment, provided it's uncontaminated the only limiting factor is the integrity of the stopper.

Good choice going with pharma.

 

[Anat]

As it's extremely pure water and benzyl alcohol, there's nothing to spoil and bacterial growth is impossible within this environment, provided it's uncontaminated the only limiting factor is the integrity of the stopper.

Good choice going with pharma.

Your posts have completely changed my approach - from using vial adapters, filtered needles, and BD needles to properly administering Tirz and bac water. Plus, learning how GLP-1 is such an amazing medication, with weight loss being just a bonus, really shifted my perspective. Even if it costs more, it’s absolutely worth it. Thanks again!