Your E2 it's very high and this is not healthy for you. 6.25 mg twice a week is far from a dose that will crash that high of E2. The nice thing is that Exemastane will lower your E2 quickly so you can get a blood test pretty soon after starting to see what effect it has. Also Exemastane can lower E2 rapidly but it is much harder to fully tank your E2 than with Anastrozole.
If I had E2 a. As high as yours I would feel like absolute shit. It's different for every guy but most like it somewhere in mid 20's to mid 30.