HCG and permanent pituitary shutdown/suppression

[5millionbucks]

I mentioned this on the other thread about HCG and post bloodwork; but I found something interesting another thread from years ago about someone using HCG while on his 3rd cycle and after that his pituitary was literally fucked. His testes were fine, but the pituitary was still messed up post pct months later. Basically he has secondary hypogonadism; if this is a possibility even with people who do low doses of anabolics; can HCG then be dangerous? One member on here said that its possible it could of been drug use; but in the thread the guy said he changed nothing and just ran HCG during his 3rd cycle and then after he wasnt the same after post pct. Here is the old thread.

https://thinksteroids.com/community/threads/hcg-and-hypothalmus-pituitary-shutdown.134274302/

 

[Drew dude]

I mentioned this on the other thread about HCG and post bloodwork; but I found something interesting another thread from years ago about someone using HCG while on his 3rd cycle and after that his pituitary was literally fucked. His testes were fine, but the pituitary was still messed up post pct months later. Basically he has secondary hypogonadism; if this is a possibility even with people who do low doses of anabolics; can HCG then be dangerous? One member on here said that its possible it could of been drug use; but in the thread the guy said he changed nothing and just ran HCG during his 3rd cycle and then after he wasnt the same after post pct. Here is the old thread.

https://thinksteroids.com/community/threads/hcg-and-hypothalmus-pituitary-shutdown.134274302/

too much HCG for too long will absolutely cause LH desensitization of the receptors in your testicules, which would result in a permanent low testosterone state that is pretty irreversible. Its only dangerous to the uninformed.

 

[5millionbucks]

too much HCG for too long will absolutely cause LH desensitization of the receptors in your testicules, which would result in a permanent low testosterone state that is pretty irreversible. Its only dangerous to the uninformed.

the guy only ran 250 IU 2x a week though

 

[Mac11wildcat]

the guy only ran 250 IU 2x a week though

For how long? What other drugs? Nothing is certain because these drugs are rarely studied for our use.

 

[5millionbucks]

To be honest I have no idea; the thread is posted on my first post in the thread though. You guys could see for yourself; the guy ran several cycles recovered fine after; and then he did HCG on one of his cycles and supposedly his pituitary was never the same. HCG does shutdown the pituitary mimicing LH so I mean it could be a factor; but I dunno. I always thought the pituitary recovered faster than the testes.

 

[T-Bagger]

This is some scary crap right here.

 

[master.on]

I mentioned this on the other thread about HCG and post bloodwork; but I found something interesting another thread from years ago about someone using HCG while on his 3rd cycle and after that his pituitary was literally fucked. His testes were fine, but the pituitary was still messed up post pct months later. Basically he has secondary hypogonadism; if this is a possibility even with people who do low doses of anabolics; can HCG then be dangerous? One member on here said that its possible it could of been drug use; but in the thread the guy said he changed nothing and just ran HCG during his 3rd cycle and then after he wasnt the same after post pct. Here is the old thread.

https://thinksteroids.com/community/threads/hcg-and-hypothalmus-pituitary-shutdown.134274302/

There's no evidence that the temporary LH/FSH shutdown by HCG can become permanent.

LH/FSH may remain suppressed if
1 there's excess androgens (i.e. bridging, TRT)
2 too much estrogen
3 SARMs used
#1 and #3 may come as undeclared ingredients in supplements

too much HCG for too long will absolutely cause LH desensitization of the receptors in your testicules, which would result in a permanent low testosterone state that is pretty irreversible. Its only dangerous to the uninformed.

high HCG doses will give you nasty gyno long before desensitizing testes, if that even happens
IMO there's no evidence for that.

 

[Drew dude]

To be honest I have no idea; the thread is posted on my first post in the thread though. You guys could see for yourself; the guy ran several cycles recovered fine after; and then he did HCG on one of his cycles and supposedly his pituitary was never the same. HCG does shutdown the pituitary mimicing LH so I mean it could be a factor; but I dunno. I always thought the pituitary recovered faster than the testes.

If he was only taking 250iu twice a week. Then it's not the HCG causing his problem. And HCG itself has no effect on the pituitary, but disrupts the HPTA by making your testis produce more testosterone then the body is telling it to with its own LH, which results in low testosterone when you come off the HCG, because of the higher estrogen levels that will be detected by the hypothalamus gland, which will then NOT send "gonadotropin-releasing hormone" or GnRH to the pituitary causing the pituitary to NOT release LH and FSH. That's why you need SERMS. I'm literally 2 weeks in to my pct as I write this... I'm taking a lot of HCG and serms.

 

[master.on]

If he was only taking 250iu twice a week. Then it's not the HCG causing his problem. And HCG itself has no effect on the pituitary, but disrupts the HPTA by making your testis produce more testosterone then the body is telling it to with its own LH, which results in low testosterone when you come off the HCG, because of the higher estrogen levels that will be detected by the hypothalamus gland, which will then NOT send "gonadotropin-releasing hormone" or GnRH to the pituitary causing the pituitary to NOT release LH and FSH. That's why you need SERMS. I'm literally 2 weeks in to my pct as I write this... I'm taking a lot of HCG and serms.

You shouldn't allow estrogen to skyrocket when using HCG.

 

[Drew dude]

You shouldn't allow estrogen to skyrocket when using HCG.

I came really close to incorporating aromisin in my pct at a low dosage. I still might, but for now the Serms are doing a good job of managing my estrogen.

 

[rpbb]

To be honest I have no idea; the thread is posted on my first post in the thread though. You guys could see for yourself; the guy ran several cycles recovered fine after; and then he did HCG on one of his cycles and supposedly his pituitary was never the same. HCG does shutdown the pituitary mimicing LH so I mean it could be a factor; but I dunno. I always thought the pituitary recovered faster than the testes.

I'm 57, have went on and off test. Have used hcg alot. Never had a problem with recovery

 

[The Terminator]

If he was only taking 250iu twice a week. Then it's not the HCG causing his problem. And HCG itself has no effect on the pituitary, but disrupts the HPTA by making your testis produce more testosterone then the body is telling it to with its own LH, which results in low testosterone when you come off the HCG, because of the higher estrogen levels that will be detected by the hypothalamus gland, which will then NOT send "gonadotropin-releasing hormone" or GnRH to the pituitary causing the pituitary to NOT release LH and FSH. That's why you need SERMS. I'm literally 2 weeks in to my pct as I write this... I'm taking a lot of HCG and serms.

I would think hCG would suppress your lh directly especially because it’s not going to raise T to supraphysiological levels. There’s only so much your balls can produce. Pretty sure it directly suppresses lh directly. Maybe @Dr JIM could clarify.

 

[Dr JIM]

I would think hCG would suppress your lh directly especially because it’s not going to raise T to supraphysiological levels. There’s only so much your balls can produce. Pretty sure it directly suppresses lh directly. Maybe @Dr JIM could clarify.

A direct negative feedback loop bt the HTPA and HCG has not been demonstrated

However HCG does suppress gonadotropin (LH and FSH) levels indirectly, as a result it’s ability to enhance gonadal androgen/estrogen secretion.

JIM

 

[The Terminator]

A direct negative feedback loop bt the HTPA and HCG has not been demonstrated

However HCG does suppress gonadotropin (LH and FSH) levels indirectly, as a result it’s ability to enhance gonadal androgen/estrogen secretion.

JIM

Didn’t know that, appreciate the info sir. So if someone was primary, like dead testes then hCG would not suppress lh/fsh because there would be no increase in T/E..

 

[Dr JIM]

Didn’t know that, appreciate the info sir. So if someone was primary, like dead testes then hCG would not suppress lh/fsh because there would be no increase in T/E..

Correct