MESO-Rx
Anabolic Steroids
Hgh IM location for pinning. Where have you pinned?
- Thread starter JG1234
- Start date
Ryu82
Member
Curious as to why your pinning IM? i do believe there are studies to indicate that pinning GH IM costs you about 30% of its absorption (referenced by Kurt Havens)
For other peptides I (LR3 Etc) have done bi's, tris, traps, calves (as well as those mentioned above) etc with a slin pin.
For other peptides I (LR3 Etc) have done bi's, tris, traps, calves (as well as those mentioned above) etc with a slin pin.
Kurt or study? that's a big difference
Ryu82
Member
He references a couple studies in several different vids and lectures, but I'm too much a lazy ass to pull and read. Ironically I used to pin GH in my delts (slin pin) until I heard him reference the 30% shit over and over so I said fook it and went to sub-q gut.
shoulder and quads for me (HGH) , if you use less water for recombine HGH is a minimun volume for injection
less immunogenic response, less chances to develop antibodies, HGH linger less in the body, so less insulin resistance supposedly
urmumsurdad30
New Member
Same place I pin my gear; Delts, Quads, VG
I'd really to know if this actually true; massive difference if...
I call It bullshit 99%
I just researched it, there are not studies proving that loss of 30% anywhere
I just researched it, there are not studies proving that loss of 30% anywhere
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Btw it seems that SC Vs IM doesn't change any immunogenic response so formation of antibodies is the same
The historical context helps explain why this question has been relevant in clinical practice. Earlier growth hormone preparations contained higher percentages of aggregated HGH, which increased immunogenicity. Modern manufacturing processes have significantly reduced these aggregates, with contemporary preparations containing less than 5% aggregated HGH. This improvement in formulation quality has likely contributed to the equivalent immunogenicity profiles now observed between administration routes.
In our case a lot less than 5% aggregates as we can all see from the dimer test we have
@readalot
444 COMPARISON OF INTRAMUSCULAR AND SUBCUTANEOUS INJECTIONS OF GROWTH HORMONE - Pediatric Research
In the treatment of growth hormone deficiency, human growth hormone (hGH) injections are given intramuscularly (IM) since subcutaneous (SC) injections are considered to be immunogenic. We have demonstrated that antibody formation is likely secondary to aggregated hGH and individual...
www.nature.com
Subcutaneous versus intramuscular growth hormone therapy: growth and acute somatomedin response - PubMed
To determine the optimal route of growth hormone administration, a comparison was made of the acute somatomedin response and chronic growth response to either intramuscular or subcutaneous growth hormone in 20 children with growth hormone deficiency. None of the children had received growth...
pubmed.ncbi.nlm.nih.gov
The historical context helps explain why this question has been relevant in clinical practice. Earlier growth hormone preparations contained higher percentages of aggregated HGH, which increased immunogenicity. Modern manufacturing processes have significantly reduced these aggregates, with contemporary preparations containing less than 5% aggregated HGH. This improvement in formulation quality has likely contributed to the equivalent immunogenicity profiles now observed between administration routes.
In our case a lot less than 5% aggregates as we can all see from the dimer test we have
@readalot
xrayphoton13
Member
Biceps
Avarice911
Member
A lot of what Kurt Havens says is mildly retarded at best so I wouldn’t go off that alone
This leaves us with a slower release with SC VS IM; I've personally been doing GH IM in my thigh every morning and I much prefer this to my stomach.Btw it seems that SC Vs IM doesn't change any immunogenic response so formation of antibodies is the same
444 COMPARISON OF INTRAMUSCULAR AND SUBCUTANEOUS INJECTIONS OF GROWTH HORMONE - Pediatric Research
In the treatment of growth hormone deficiency, human growth hormone (hGH) injections are given intramuscularly (IM) since subcutaneous (SC) injections are considered to be immunogenic. We have demonstrated that antibody formation is likely secondary to aggregated hGH and individual...www.nature.com
Subcutaneous versus intramuscular growth hormone therapy: growth and acute somatomedin response - PubMed
To determine the optimal route of growth hormone administration, a comparison was made of the acute somatomedin response and chronic growth response to either intramuscular or subcutaneous growth hormone in 20 children with growth hormone deficiency. None of the children had received growth...pubmed.ncbi.nlm.nih.gov
The historical context helps explain why this question has been relevant in clinical practice. Earlier growth hormone preparations contained higher percentages of aggregated HGH, which increased immunogenicity. Modern manufacturing processes have significantly reduced these aggregates, with contemporary preparations containing less than 5% aggregated HGH. This improvement in formulation quality has likely contributed to the equivalent immunogenicity profiles now observed between administration routes.
In our case a lot less than 5% aggregates as we can all see from the dimer test we have
@readalot
Yeah it's just preference, SC can yield higher IGF1 number for what I have read.
Apart from that doesn't change much
Steve0691
New Member
Exactly what i do, shoulders if im wearing a t shirt, forearm if im wearing a longsleeve lol
AlexDavis43
Member
Btw it seems that SC Vs IM doesn't change any immunogenic response so formation of antibodies is the same
444 COMPARISON OF INTRAMUSCULAR AND SUBCUTANEOUS INJECTIONS OF GROWTH HORMONE - Pediatric Research
In the treatment of growth hormone deficiency, human growth hormone (hGH) injections are given intramuscularly (IM) since subcutaneous (SC) injections are considered to be immunogenic. We have demonstrated that antibody formation is likely secondary to aggregated hGH and individual...www.nature.com
Subcutaneous versus intramuscular growth hormone therapy: growth and acute somatomedin response - PubMed
To determine the optimal route of growth hormone administration, a comparison was made of the acute somatomedin response and chronic growth response to either intramuscular or subcutaneous growth hormone in 20 children with growth hormone deficiency. None of the children had received growth...pubmed.ncbi.nlm.nih.gov
The historical context helps explain why this question has been relevant in clinical practice. Earlier growth hormone preparations contained higher percentages of aggregated HGH, which increased immunogenicity. Modern manufacturing processes have significantly reduced these aggregates, with contemporary preparations containing less than 5% aggregated HGH. This improvement in formulation quality has likely contributed to the equivalent immunogenicity profiles now observed between administration routes.
In our case a lot less than 5% aggregates as we can all see from the dimer test we have
@readalot
About that one point in particular (see bold): see here (copied and pasted below)
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