Thegodofwar
New Member
100 percent it’s from the hcg….
Do you realise that hcg raises e2 through the roof?
Cmon man you must know this
MESO-Rx
Anabolic Steroids
High e2 on 2.5mg anastrozole per week
- Thread starter HUGE McBIGLARGE
- Start date
Do you realise that hcg raises e2 through the roof?
Cmon man you must know this
Thegodofwar
New Member
Brother you are using hcg everyday what do you expect???
Cut out the hcg and then retest you will realise I am right.
Of anyone tells you otherwise I would be weary of their advice.
HUGE McBIGLARGE
Member
Yeah that’s what I’m gonna do.
Im gonna do just T and proviron, AI the e2 into range, then retest twice to confirm my e2 is stable. Then add HCG at the same dose for a month and test again to see how much my e2 rises. If it is the HCG I’ll then have a big think about how much I regret buying a few years worth of HCG
In addition, if you really want to go down the rabbit hole do a series of experiments with (+)hCG at different letro dosing and populate your dose response curve
.Good luck with the (-)hCG experiment.
HUGE McBIGLARGE
Member
Yeah I’ll consider that. Bit harder for me to get letro thoughIn addition, if you really want to go down the rabbit hole do a series of experiments with (+)hCG at different letro dosing and populate your dose response curve
Good luck with the (-)hCG experiment.
I might just ditch the HCG entirely if I feel fine. I’ve had a vasectomy anyway so it’s not like I wanna preserve fertility. I just wanted the theoretical downstream hormone effects from the HCG. But if it means indiscriminately inhibiting aromatase, I think I’d fare better with a low/no AI dose than a big AI dose and HCG.
Agreed. Was just speaking more hypothetically. Take care of yourself. Personally I can't justify running an AI long term for myself.
HUGE McBIGLARGE
Member
Thanks man. Glad I’ve got a plan going forward now.
And thanks to everyone else for the help
I have used HCG for over 20 years regularly with no issues. Many have no problem when taking it. But if you have some studies showing different i am more then willing to read them.. Thanks.
Grey Spartan
New Member
I second this. I did an experiment, took 350-400iu Every other day and dropped the AI. My estrogen only raised to 40. I was also taking 100mg Test C twice a week.
HUGE McBIGLARGE
Member
any idea why my e2 was so high then?
As I wrote before...
Taking HCG increases aromatase activity in Leydig cells in the testes. Under normal circumstances, there is roughly 20% aromatization of TST in the testes. If men start taking AAS, which are suppressive and reduce the production of endogenous TST in the testes, aromatization in the testes will decline. Adding HCG to the cycle will in turn return it to its original level, which should not exceed 20% at normal HCG doses of 250 to 500 iu every 3 to 4 days. In other words, at normal doses of HCG, you don't have to worry about too much increased aromatization activity and therefore high E2 levels.
“Hcg increases e2 to the roof is just fucking broscience”
Taking HCG increases aromatase activity in Leydig cells in the testes. Under normal circumstances, there is roughly 20% aromatization of TST in the testes. If men start taking AAS, which are suppressive and reduce the production of endogenous TST in the testes, aromatization in the testes will decline. Adding HCG to the cycle will in turn return it to its original level, which should not exceed 20% at normal HCG doses of 250 to 500 iu every 3 to 4 days. In other words, at normal doses of HCG, you don't have to worry about too much increased aromatization activity and therefore high E2 levels.
“Hcg increases e2 to the roof is just fucking broscience”
Whats your test on bloods?
Shbg?
do 500ui 2x week instead of pinning every day, max peak in e2 is around 24hr from your pin
HUGE McBIGLARGE
Member
I don’t have a better explanation though.
The below are the results of a test I did a few years ago while on 1000mg test undeconate every 70 days. No HCG. No AI. E2 nice and normal.
The below was 6 months ago. I was on the 54mg TE EoD for about a month at the time. 1mg anastrozole per week. I had stopped Testogel for 96 hours; enough for a full washout. 200iu HCG every other day.
And here’s what I last tested as. Less TE, 2.5x the AI, and 50% more HCG dosed daily instead of EOD. I also took 0.5mg anastrozole 16 hours prior to the blood draw, rather than 24 hours with the previous test
The only other explanation is that my testosterone was somehow much higher on those doses, but I doubt it. Or maybe that the mt2 or pt141 is somehow estrogenic.
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HUGE McBIGLARGE
Member
Testosterone? Not sure. I can guess around 50nmol/l, but I didn’t test it as most of the time the tests cap at 52.
SHBG wasn’t tested either. Likely around 30nmol/l
Would daily pinning cause a disproportionate rise in e2 relative to the total weekly dose? If so, that might explain it.
Grey Spartan
New Member
We all respond differently. The HCG defiantly raises your e2, so start with that and check blood work. Pinning daily could cause a build up, but I have never tried it on myself so I can not give you a "for sure" answer.
To be clear for future readers, the post I shared shares references that indicate letro absolutely does cross into testes.
