how to make transdermal testosterone?

[callisto]

i have read about apparent neurotoxicity of BA but is this a possibility if you use it transdermal? if not, whats the best transdermal solvent that has the least toxic effects, highest absorbtion rate and least skin irritation?
importance is
skin irritation>toxicity>absorbtion

 

[john_snow]

i have read about apparent neurotoxicity of BA but is this a possibility if you use it transdermal? if not, whats the best transdermal solvent that has the least toxic effects, highest absorbtion rate and least skin irritation?
importance is
skin irritation>toxicity>absorbtion

If absorption is the last priority I guess the answer is the 96% ethanol + isopropyl myriatate formula

If I understood correctly, it’s something like this:

96% ethanol + IPM = 30% absorption approx, least irritation, least toxicity

Benzyl Alcohol + IPM = 50% absorption approx, with the risk of more toxicity

DMSO = nearly 100% absorption, but the most irritation, the need to be careful with cleaning the skin and the risk of mobilizing heavy metals in your body

Don’t take it as face value, I might be wrong, that’s the summary I got to my best understanding by reading this topic here and on ray peats forum

 

[Chris6]

New accounts ? Where ?

Dude, I initiated the homemade transdermal trend two years ago via different forums, I'm completely comfortable with this success and I have no issues recommending different formulas when necessary.

Back to the topic : do you have an opinion on BA ?

So then stop creating new accounts on RPF over and over again every time you switch a formula or hormone protocol.

I don't have an opinion on it. I was just following your older posts about it and some days you like it and some days you don't. You said BA causes you blurry vision and in an older you post here you say salvo doesn't absorb because it uses benzyl alcohol. Pls make up your mind.

 

[callisto]

If absorption is the last priority I guess the answer is the 96% ethanol + isopropyl myriatate formula

If I understood correctly, it’s something like this:

96% ethanol + IPM = 30% absorption approx, least irritation, least toxicity

Benzyl Alcohol + IPM = 50% absorption approx, with the risk of more toxicity

DMSO = nearly 100% absorption, but the most irritation, the need to be careful with cleaning the skin and the risk of mobilizing heavy metals in your body

Don’t take it as face value, I might be wrong, that’s the summary I got to my best understanding by reading this topic here and on ray peats forum

could i combine the 96% ethanol with ipm and maybe 10% dmso for better absorbtion? or would that small amount alone be too irritating?

 

[tesarpaul]

could i combine the 96% ethanol with ipm and maybe 10% dmso for better absorbtion? or would that small amount alone be too irritating?

The thing is you dont want the ethanol to get into your bloodstream. So I would advoid the combination of DMSO with other stuff.

 

[Deleted member 59947]

You said BA causes you blurry vision and in an older you post here you say salvo doesn't absorb because it uses benzyl alcohol.

How are the two mutually exclusive ?

Yes BA causes blurry vision, and it does leave an oily residue on the skin that doesn't go away.

That doesn't mean it's not a tremendous solvent and penetration enhancer.

 

[Deleted member 59947]

So then stop creating new accounts on RPF over and over again every time you switch a formula or hormone protocol.

I create new accounts on RPF because I keep being banned for reasons independant of hormone protocole changes, namely because cry-babies report me when they can't handle my straight-forward way of writing.

If it was up to me I'd still have my original account, while changing hormone protocols because I don't pretend to know it all, I keep experimenting and changing protocols when one works better than the other.

It's easy to comment on what people do in life, it's harder to actually do

 

[BouleauBoulot]

I create new accounts on RPF because I keep being banned for reasons independant of hormone protocole changes, namely because cry-babies report me when they can't handle my straight-forward way of writing.

If it was up to me I'd still have my original account, while changing hormone protocols because I don't pretend to know it all, I keep experimenting and changing protocols when one works better than the other.

It's easy to comment on what people do in life, it's harder to actually do

Maybe Charlie doesn't like you. He banned me simply for "bothering" him in a private message with a simple request, yet written in a courteous manner.

 

[tesarpaul]

Did anyone try the testosterone undecanoate instead of test base?

The price is the same as test base but the oral availibility should be better.

​

 

[callisto]

The thing is you dont want the ethanol to get into your bloodstream. So I would advoid the combination of DMSO with other stuff.

okay, i will order a small amount of dmso and test my skins reaction to it as it has the highest absorbtion rate and isnt toxic as BA
if i react vad i will probably just use the ethanol + ipm combo

 

[Deleted member 59947]

okay, i will order a small amount of dmso and test my skins reaction to it as it has the highest absorbtion rate and isnt toxic as BA
if i react vad i will probably just use the ethanol + ipm combo

DMSO is a heavy metal chelator.
We are all burdened with metals, it will stir them around without evacuating them, causing neurological issues.

You won't notice this right away, don't use DMSO.

 

[callisto]

DMSO is a heavy metal chelator.
We are all burdened with metals, it will stir them around without evacuating them, causing neurological issues.

You won't notice this right away, don't use DMSO.

okay, thank you

 

[pstnf1]

Did anyone try the testosterone undecanoate instead of test base?

The price is the same as test base but the oral availibility should be better.

​

I was wondering the same, if anyone's tried it.

 

[john_snow]

Anyone had the issue with water retention and solved it? I'll stop applying the T solution because I hate how my face looks.

Back to Pansterone + Kuinone + Androsterone until I have a plan to manage water retention on T

 

[Deleted member 59947]

Anyone had the issue with water retention and solved it? I'll stop applying the T solution because I hate how my face looks.

Back to Pansterone + Kuinone + Androsterone until I have a plan to manage water retention on T

My face used to look very bloated on the cream from the pharmacy.

I look lean with my homemade ethanol + IPM eventhough the concentration is the same as the cream.

 

[Chris6]

How are the two mutually exclusive ?

Yes BA causes blurry vision, and it does leave an oily residue on the skin that doesn't go away.

That doesn't mean it's not a tremendous solvent and penetration enhancer.

Explain to us why salvo doesn't absorb then. Especially if it contains the most "tremendous solvent" benzyl alcohol?

 

[Chris6]

I create new accounts on RPF because I keep being banned for reasons independant of hormone protocole changes, namely because cry-babies report me when they can't handle my straight-forward way of writing.

If it was up to me I'd still have my original account, while changing hormone protocols because I don't pretend to know it all, I keep experimenting and changing protocols when one works better than the other.

It's easy to comment on what people do in life, it's harder to actually do

Interesting...I hope "Matestube" and "Santosh" are both doing well with their post AI issues.

 

[tesarpaul]

My face used to look very bloated on the cream from the pharmacy.

I look lean with my homemade ethanol + IPM eventhough the concentration is the same as the cream.

Same. I got some water retention from the beggining. I gained like 5 kg.

But I did a little cut plus I started the ethanol formula a I dont hold much water now. But I was using DHEA And DHT which could also help.

 

[Deleted member 59947]

Explain to us why salvo doesn't absorb then. Especially if it contains the most "tremendous solvent" benzyl alcohol?

I just explained to you that benzyl alcohol stays on the skin as an oily residue, although it makes the raw powder penetrate the dermis layer.

I'm starting to think you can't read or comprehend.

 

[Deleted member 59947]

Interesting...I hope "Matestube" and "Santosh" are both doing well with their post AI issues.

You forgot a few of my accounts :

TheBeard
Madato
Zibernet
Matestube
Santosh

I'm doing fine thanks to experimenting and not just commenting on other people's life while mine is passing by