how to make transdermal testosterone?

[callisto]

Depends on if you want to shoot your numbers into the stratosphere or not. Personally I find 25mgs of DHT to be sufficient if it's in DMSO. I think people tend to forget DMSO increases dermal absorption to almost 100%, certainly 90%. It comes with severe drawbacks though. The skin irritation alone is almost not worth it for me.

What are you trying to achieve with DHT? I find the smaller dosages help best, likely due to binding SHBG and freeing up some test. But the larger dosages (without T) will suppress and likely be too GABAergic. Might actually drop libido. Scrotal T would be the best way to raise DHT I think, while keeping a more favorable ratio of T/DHT/E2.

so you do 25mg 1x day?
interesting.
i get very strong anti-anxiety effects and big libido boost on it, also increased endurance, thats why im using it. weirdly my hair looks and feels thicker and i shed less since using it when usually the opposite would happen.

 

[lars49]

so you do 25mg 1x day?
interesting.
i get very strong anti-anxiety effects and big libido boost on it, also increased endurance, thats why im using it. weirdly my hair looks and feels thicker and i shed less since using it when usually the opposite would happen.

Oh it's definitely anti-anxiety, and in the lower dosages pro-libido as well. I'm not sure what makes the lower dosages (25mgs) pro-libido and the higher dosages (anything over 75mg) counterintuitive. But my speculation is the SHBG binding in the lower dosages, and the potent GABA activity at the higher dosage.

I'll do 25mgs in DMSO. I would probably do a higher dose in ethanol since the absorption would be lower. But actually I'm not using it much at all right now. I prefer the scrotal testosterone application for my DHT. I think applying the T directly to the balls will encourage DHT production while providing enough testosterone to keep me even keel.

 

[Deleted member 59947]

DHEA aromatizes much more easily than T.

I have no idea where this idea comes from, it's absolutely not the case.
I use 500mg DHEA transdermal every day, I have zero water retention and my joints slightly hurt.
Same with 500mg oral DHEA.

Whereas with even 50mg transdermal testosterone a day I have a bloated face and a raging estrogenic libido.

 

[callisto]

I have no idea where this idea comes from, it's absolutely not the case.
I use 500mg DHEA transdermal every day, I have zero water retention and my joints slightly hurt.
Same with 500mg oral DHEA.

Whereas with even 50mg transdermal testosterone a day I have a bloated face and a raging estrogenic libido.

what dosages of dht in dmso/ethanol+ips have you used and what would be the range to use, as in like minimum 10mg ed for noticeable effects and maximum 150mg ed?

 

[lars49]

I have no idea where this idea comes from, it's absolutely not the case.
I use 500mg DHEA transdermal every day, I have zero water retention and my joints slightly hurt.
Same with 500mg oral DHEA.

Whereas with even 50mg transdermal testosterone a day I have a bloated face and a raging estrogenic libido.

Your unique anecdotal doesn't make it a generalization for all or even most men. You're the same guy from RPF that crashed your E2 with aromatase inhibitors, and likely altered your steroidogenic enzymatic activity as well. The science is very clear about DHEA's aromatizing capability. I've seen endless amounts of men across forums complain about estrogen related symptoms from too much DHEA.

 

[BouleauBoulot]

Your unique anecdotal doesn't make it a generalization for all or even most men. You're the same guy from RPF that crashed your E2 with aromatase inhibitors, and likely altered your steroidogenic enzymatic activity as well. The science is very clear about DHEA's aromatizing capability. I've seen endless amounts of men across forums complain about estrogen related symptoms from too much DHEA.

I also have no symptoms of excess e2 even though I am on DHEA.

 

[BouleauBoulot]

@Goingstronger how does DHT feel compared to testosterone?

 

[Inthemixer]

True, but I don't care if I have low testosterone if my DHT is very high, as long as the anabolism remains a decent minimum.

Did you try topical DHEA yet

 

[BouleauBoulot]

Did you try topical DHEA yet

Yes, i'm currently on it

 

[Inthemixer]

Yes, i'm currently on it

How’s it going? I’m interested in trying as well

 

[BouleauBoulot]

How’s it going? I’m interested in trying as well

I feel clearer/smarter than on testosterone. I feel just as strong physically see more. The only problem is that my beard grows slower, and my libido is pretty low.

That said it may be because I'm low in e2, my lips are very chapped and pale and I have little water retention, I sometimes have knee pain and again not too much libido, erections are good but I have to force myself to excite myself beyond one orgasm a day, and if I do myself my orgasms are weaker and my loads are miserable, while having symptoms of stimulated prostates because I literally want to piss every 5 minutes there night if something upsets me and gets my adrenaline pumping. It remains easier to sleep and relax at night than under testosterone.

 

[Gjl1020]

I feel clearer/smarter than on testosterone. I feel just as strong physically see more. The only problem is that my beard grows slower, and my libido is pretty low.

That said it may be because I'm low in e2, my lips are very chapped and pale and I have little water retention, I sometimes have knee pain and again not too much libido, erections are good but I have to force myself to excite myself beyond one orgasm a day, and if I do myself my orgasms are weaker and my loads are miserable, while having symptoms of stimulated prostates because I literally want to piss every 5 minutes there night if something upsets me and gets my adrenaline pumping. It remains easier to sleep and relax at night than under testosterone.

I've also noticed on a few occasions that dhea (orally) boosts my libido more so than test (im). But I wasn't sure if some other factors were involved. You say that you feel just as strong physically on dhea. Do you have actual experience pinning test, or just creams?
Also, you say a lot about when your e2 is up or down. Do you ever get bloods to substantiate, or is it purely subjective?

 

[Deleted member 59947]

@Goingstronger how does DHT feel compared to testosterone?

Irritable, low libido, cracky joints, better mental clarity.

I feel better physically on testosterone, but my mind gets more agitated and cloudy.

 

[BouleauBoulot]

I've also noticed on a few occasions that dhea (orally) boosts my libido more so than test (im). But I wasn't sure if some other factors were involved. You say that you feel just as strong physically on dhea. Do you have actual experience pinning test, or just creams?
Also, you say a lot about when your e2 is up or down. Do you ever get bloods to substantiate, or is it purely subjective?

I already did a little enanthate cure by injection that I finally quickly stopped because of a pip that dissuaded me from starting again.

Then I came across goingstronger creams solution on the RPF.
I am several months under testosterone cream and therefore now DHEA.

I did several blood tests and my estradiol was actually higher before starting testosterone than after several months of base testosterone.
I rely on the symptoms which are quite clear:
-If I bloat, sweat like a pig at night if it's hot, jerk off 6 times a day fantasizing about BDSM, am very curious and quick-witted, I'm relatively sure of be high in estrogen.

-If I have low water retention, chronically chapped lips, little to very little libido, routine/just want to eat cakes in bed and do nothing, I'm pretty sure my estrogen is low or eclipsed by DHT (among others).

Whether it's testosterone or transdermal DHEA, I feel like it's going from the first to the second little by little.

 

[Bugsy123]

I’d love to see someone homebrew testosterone Cream with lipoderm cream.

 

[ghostpharma]

I’d love to know about the tren base, following for sure.

I’m going to attempt to make

99.9% dsmo + test base

&

96% everclear ethanol
3% IPM
+ test base

I want to try them both and potentially come up with something for my local clients that are cruising in between cycles

 

[Deleted member 59947]

I’d love to know about the tren base, following for sure.

I’m going to attempt to make

99.9% dsmo + test base

&

96% everclear ethanol
3% IPM
+ test base

I want to try them both and potentially come up with something for my local clients that are cruising in between cycles

Those are my two formulas.

I can save you time by telling you already the pros and cons of both :

DMSO
Pros : high levels, mass increase
Cons : HM chelator, burns, you smell like shrimp even if it's the purest DMSO

Ethanol + IPM
Pros : easy application, good enough levels
Cons : none

 

[tesarpaul]

Those are my two formulas.

I can save you time by telling you already the pros and cons of both :

DMSO
Pros : high levels, mass increase
Cons : HM chelator, burns, you smell like shrimp even if it's the purest DMSO

Ethanol + IPM
Pros : easy application, good enough levels
Cons : none

@ghostpharma I would add to the Ethanol formula that you will not see any muscle gains plus you will most likely experience the negative mental effects which we have disscued few pages back.

 

[BouleauBoulot]

Someone tried LSD under testosterone here ? lol
I had a drop when I was still on testosterone not long ago, it was quite different than usual.
Much less mental and much more physical, and the halucinations were much "hotter" and tropical. When I was totally natty it was much colder and "metallic".

I wonder what it would do on dhea, tren...

 

[AlwaysHungry]

It's quite similar (to a lesser extent) to what you might feel going down ketamine.

I believe that even though 5ar activity increases significantly, even to the point of spitting out e2, testosterone levels are so high that it overwhelms other downstream steroids in the competition for androgen receptors in the brain.

DHT and probably androsterone are actually much more GABAergic than testosterone, so you end up with excessive glutaminergic activity.

-You seem too mentally "wired", easily causing insomnia.
-Paradoxically not too much physical energy, especially if you lack sleep.
Generally not as "grounded" outwardly as without testosterone
-You lose part of your ability to socialize, even to "delirious", you can still make jokes and be sociable if for some reason dopamine is high, but otherwise you just stare into space with a fish face and just have simple conversations with a monotonous tone. Most of the time if you force it is unnatural and you find yourself not knowing how to tone down your sentences or that kind of thing.
-Nothing to do with autism, but in addition to being more likely to have insomnia you are less resilient to lack of sleep. You lose it cortisol relay to forcibly stimulate the CNS, if I have slept badly for several days I can feel sedation and crash about half an hour after applying the base testosterone cream. If the excess lack of sleep is too strong, I even have symptoms of Addison's disease like muscle spasms.

That's how I feel

Damn man all this caused by testosterone? All this applies to injectable also ?
I'm using testing for years and I have noticed I'm less social boring conversations monotonous tone bored all the time etc.
I drop testosterone from time to time to feel good and I've noticed without testo im way more social I can talk again while on test I don't talk that much. If I'm not on test I'm way more social athletic have good mood but my libido is ZERO.