I really like Modafinil - even at low doses

I have to say, you’re doing a very good job talking me into taking it more regularly (not that you’re trying to).

I am very pro GLP1. I just started Retatrutide almost four weeks ago.

I take low dose lithium (10mg) and Telmisartan (40mg), along with aggressive ApoB reduction, all which have shown to be potentially anti dementia (I also take pregnenolone which could also be useful for brain health). But none of these things have a “smart drug” effect like Modafinil.

That’s being said, I do personally notice a slight increase in blood pressure on days I take Modafinil. Perhaps this is short lasting with continuous use, but not sure.

I haven’t read the whole thread. How much do you personally take?
I am curious about lithium, do you find it has any mood stabilizing effects at 10mg?

I could use something like that, I am not prone to anger but yo-yo between hypomania and depression more often than I'd like to admit.
 
I am curious about lithium, do you find it has any mood stabilizing effects at 10mg?

I could use something like that, I am not prone to anger but yo-yo between hypomania and depression more often than I'd like to admit.
It’s hard to say what I notice from taking low dose lithium, especially since I take a number of things so it’s hard to point out what is doing what. I have also been taking it for years now, so being on it is normal to me. It just has some promising data for preventing cognitive decline and it’s cheap so I take it just in case it works. I don’t see any harm in trying it.
 
I am curious about lithium, do you find it has any mood stabilizing effects at 10mg?

I could use something like that, I am not prone to anger but yo-yo between hypomania and depression more often than I'd like to admit.

You may find low dose (15mg) ariprazole useful. It's called an "atypical antipsychotic" but a very effective mood stabilizer at low doses with minimal sides. Known as "Abilify" it's available from the India PCT vendors.

Friend of mine who really likes it said "Ariprazole gets rid of the asshole".
 
You may find low dose (15mg) ariprazole useful. It's called an "atypical antipsychotic" but a very effective mood stabilizer at low doses with minimal sides. Known as "Abilify" it's available from the India PCT vendors.

Friend of mine who really likes it said "Ariprazole gets rid of the asshole".
Very interesting suggestion, I have never heard anyone talk about this drug before. I took some time to briefly look into whether this is worth a shot but I think it's not for me. Reasons being:

* Price, $35-60 per month is a large percentage of my current PED budget
* Low availability (out of 3 PCT vendors I know, only 1 carried it and it ships from Turkey)
* I don't want to add 5th psychoactive drug on top of bupropion XL 300 mg, Vyvanse 50 mg, modafinil 200 mg, eszopiclone 2mg (only the first 2 are prescribed)
* It carries a higher risk of side effects compared to Lithium (I am assuming that 10 mg of lithium orotate from iHerb won't be as strong as an actual pharmaceutical drug, I could be wrong)

Bupropion XL 300 mg has helped a ton with the yo-yoing I mentioned, I was a complete wreck before starting that a couple years ago. I had literal bedridden depression for a couple months as well as moments I would call hypomanic behaviour (never done anything insane, it is more like setting unachievable goals for myself and hyperfocusing on them at the cost of everything else especially sleep, day job, relationships).

I'd say Bupropion has drastically decreased the intensity and duration of both depression and hypomania, but I still have moments that slow me down and lower my quality of life. The improvement after starting bupropion was rapid and noticeable to people around me.

I can tell you're not a fan of Vyvanse and amphetamines/stimulants but I would say that has helped me become way more stable too as well as helping me perform drastically in day to day and work tasks. I have been on break from Vyvanse for about 20 days since starting modafinil.

I am still experimenting with modafinil and eszopiclone trying to increase wakefulness and finally fix my sleep (this time for real bro, I promise!). The more I type it sounds like I should stay away from lithium too for now since I have only added in these 2 psychoactive drugs less than 30 days ago.
 
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