I have to say, you’re doing a very good job talking me into taking it more regularly (not that you’re trying to).This is where we have a conundrum similar to GLPs. "These benefits only apply to the obese, or diabetics.".
There is significant evidence suggesting benefits for "healthy" people using either Moda or GLPs, however, the ethics review for medical research required for approval of studies doesn't allow for long term experimentation in those without a "problem" that's supposed to be the target of the research. So we see a benefit, like white matter increasing after long term use "in narcolepsy" sufferers, and "stroke victims with fatigue", and the temptation is to dismiss these effects as being limited to those groups (which is always possible of course), but when you dig into the mechanism of action, it's not really anything to do with those conditions, and could very well apply to everyone, but modern research methods simply doesn't accommodate experimentation for "enhancement" purposes, only for treating illness.
There's a drug called "dalfampridine" that's showing the ability to boost "working memory", a major element of cognition closely associated with success and accomplishment, significantly, in healthy people. It's a drug for multiple sclerosis, and TLDR, improves the "electrical insulation" around nerves to prevent signals from "leaking" and therefore work more efficiently. It appears quite safe, with the major risk being making nerves too efficient, inducing tremors at too high of a dose.
It sounds like it's potentially an amazing physical and cognitive performance enhancer. Yet, studies on healthy people have been limited to 3 days. I'm eager to get my hands on some from India pharma.
I am very pro GLP1. I just started Retatrutide almost four weeks ago.
I take low dose lithium (10mg) and Telmisartan (40mg), along with aggressive ApoB reduction, all which have shown to be potentially anti dementia (I also take pregnenolone which could also be useful for brain health). But none of these things have a “smart drug” effect like Modafinil.
That’s being said, I do personally notice a slight increase in blood pressure on days I take Modafinil. Perhaps this is short lasting with continuous use, but not sure.
I haven’t read the whole thread. How much do you personally take?
Last edited: