Interesting results on daily vs E3.5 day testosterone injections

[readalot]

Could any difference in PK between TE and TC be attributable to the ester structure? Even if they're only 1-carbon chain difference, they have different structures. TC has that cyclic structure of carbons compared to TE's linear structure. Could that result in more resistance to enzymatic hydrolysis?

Theoretically, yes. In practice, not much...

https://forums.steroid.com/attachments/hormone-replacement-therapy-low-testosterone-treatment-anti-aging/168098d1488661137-1-2-life-testosterone-myth-injecting-every-2-weeks-better-t-cyp-kinetic-curve-2.png

Forgive me for not pulling this from original reference. Don't have that pdf handy at the moment. I am familiar with the figure though.

 

[readalot]

SteroidPlotter cites that study in reaching their PK numbers.

I guess the steroid plotter guys can't read. From the paper:

The median post hoc half-life was calculated to be 4.05 days for tT.

 

[readalot]

@lift4lyfe

If you want to estimate the number from Table 2 in the paper:

For those who are struggling on TRT

I've been thinking about this thread lately. Any theories on why you seem to respond better on 1x week versus daily? I've read a number of accounts from med-high SHBG guys like you who do better on less frequent injections. I think it’s just the simple mechanism of the medication itself and...

www.excelmale.com

3.4 to 4.4 days.

 

[Benf15harp]

SteroidPlotter is for entertainment purposes only.