Low-dose clen cycles

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I'm still at 60mcg today, and I did cardio for the first time during my cut; 30 mins was a joke lol; It makes it so easy.

I don't think I'm going to higher, as I'm seeing results weekly; I rather be on it longer if there is no downregulation and no threat to my heart heath at this dose.
So you went right to clen in your cut, before adding in even a little cardio?
 
So you went right to clen in your cut, before adding in even a little cardio?
Yes, the plan was to get lean without cardio, focusing mostly on the deficit and high-volume training, because the leanness I want to achieve can be achieved without it. I'm look for 10-12%; I'm not trying to get to 7%.
 
Yes, the plan was to get lean without cardio, focusing mostly on the deficit and high-volume training, because the leanness I want to achieve can be achieved without it. I'm look for 10-12%; I'm not trying to get to 7%.
You are so ass backwards.

If you aren't even trying to get lean, all the more reason why you don't need clen in the first place
 
Ive never tried Clen before and I’m not a huge fan of stimulants in general but I’m on the tail end of a cut. Do you think I could or would see some benifits from 4-6 weeks max does of 40. My thoughts would be 20 for two weeks then up to 40 for the remaining make sure I’m comfortable with the sides if any or would this just be a waste.
 
You are so ass backwards.

If you aren't even trying to get lean, all the more reason why you don't need clen in the first place
I am trying to get lean: I've been dieting since March 1st, just going slowly.

I'm enjoying the 60mcg ED, I'm wondering if it would be damaging to my heart if I just kept taking this dose until I reach my goal, which would probably be few more months.
 
Ive never tried Clen before and I’m not a huge fan of stimulants in general but I’m on the tail end of a cut. Do you think I could or would see some benifits from 4-6 weeks max does of 40. My thoughts would be 20 for two weeks then up to 40 for the remaining make sure I’m comfortable with the sides if any or would this just be a waste.
I've taken clen before and never went above 40 until recently; and yes you will see a benefit at 40, I think.
 
I am trying to get lean: I've been dieting since March 1st, just going slowly.

I'm enjoying the 60mcg ED, I'm wondering if it would be damaging to my heart if I just kept taking this dose until I reach my goal, which would probably be few more months.
I don't like clen, makes me feel like shit. I look at it as a necessary evil when prep time comes around, but I dread it.

I'm fairly conservative in my use and try to remain as health conscious as possible, so I personally wouldn't be doing that, but who's to say for sure if, and what extent of damage that could cause, if it does.

Nobody cares about your health as much as you do, so just gonna have to make the best call on how risk adverse you're willing to be or not be.
 
I don't like clen, makes me feel like shit. I look at it as a necessary evil when prep time comes around, but I dread it.

I'm fairly conservative in my use and try to remain as health conscious as possible, so I personally wouldn't be doing that, but who's to say for sure if, and what extent of damage that could cause, if it does.

Nobody cares about your health as much as you do, so just gonna have to make the best call on how risk adverse you're willing to be or not be.
Well, my HR is only 88 resting, but 150 when I do stepper. I'm not feeling any sides like headaches, cramps, or losing any sleep, as they have subsided. I don't see the point of going any higher.

Do you subscribe to the idea that clen loses potency and needs to be cycled, or the opposite: that one can take it as long as they need and it's not diminished?

Clen makes me feel a bit drained, but once I start working out or doing cardio, suddenly I am energized. I do feel, however, the rep output has diminished, when it comes to explosive movements like bench.
 
Well, my HR is only 88 resting, but 150 when I do stepper. I'm not feeling any sides like headaches, cramps, or losing any sleep, as they have subsided. I don't see the point of going any higher.

Do you subscribe to the idea that clen loses potency and needs to be cycled, or the opposite: that one can take it as long as they need and it's not diminished?

Clen makes me feel a bit drained, but once I start working out or doing cardio, suddenly I am energized. I do feel, however, the rep output has diminished, when it comes to explosive movements like bench.
I don't know enough about it's mechanisms, and I haven't used it long enough to say for sure one way or another. Like I said, I avoid it like the plague, so I don't even have a personal anecdote on if I felt like it lost efficacy.


That's exactly why I don't like it, feel ran down throughout the day, at the gym is always fine, but rest of the day just uncomfortable.
 
I'm on day 8 of 20mcg of clen ED; seems to be doing the job. Does anyone else just take a straight dose, rather than titrating up? I may go up to 40mcg and stick with that next week.

I've read people go up to 120 by titrating up, but I've never gone passed 40 or 60. I've also read that clen doesn't downregulate, its just the sides go away so people don't think it's working anymore, but it is, so these short blasts aren't necessary.
@Type-IIx what's your take on this? Does clen need to be cycled, or is that a myth? I'm still seeing results 7 weeks in, but my body is starting to feel "drained" from it now. Feeling like taking a break this week.
 
@Type-IIx what's your take on this? Does clen need to be cycled, or is that a myth? I'm still seeing results 7 weeks in, but my body is starting to feel "drained" from it now. Feeling like taking a break this week.
It should be cycled because β2AR are subject to rapid tachyphylaxis (desensitization) because the receptor is a target for phosphorylation and because it binds β-arrestin, an accessory protein involved in G protein-coupled receptor desensitization.

To illustrate by way of example, β-arrestin -mediated G protein-coupled receptor interactions are also germane to heroin & morphine tolerance.

Doses have to increase to elicit the same results, and one should not use long-term.
 
It should be cycled because β2AR are subject to rapid tachyphylaxis (desensitization) because the receptor is a target for phosphorylation and because it binds β-arrestin, an accessory protein involved in G protein-coupled receptor desensitization.

To illustrate by way of example, β-arrestin -mediated G protein-coupled receptor interactions are also germane to heroin & morphine tolerance.

Doses have to increase to elicit the same results, and one should not use long-term.
Wow, thanks.

I actually skipped it today, since I've been on for 8 weeks, and my body just feels drained for being on so long. I know it's not the best drug for the heart, but I didn't go beyond 60mcg per day.

I plan of staying off through my vacation coming up in two weeks, so that will give my body a decent break.

So how long does the body get "used" to a specific dose? Is it two weeks, as the bro science used to claim, and cycle off? If someone wanted to go beyond that, they would have to increase the dose to stay on? Sounds like a waste of tabs to do that.

What do you recommend would be the best way to use this compound?
 
Wow, thanks.

I actually skipped it today, since I've been on for 8 weeks, and my body just feels drained for being on so long. I know it's not the best drug for the heart, but I didn't go beyond 60mcg per day.

I plan of staying off through my vacation coming up in two weeks, so that will give my body a decent break.

So how long does the body get "used" to a specific dose? Is it two weeks, as the bro science used to claim, and cycle off? If someone wanted to go beyond that, they would have to increase the dose to stay on? Sounds like a waste of tabs to do that.

What do you recommend would be the best way to use this compound?
It's rapid. You're kind of asking me to do the impossible here, predict the extent and degree of tachyphylaxis for you.

I wouldn't be surprised that with 1.5 - 2 weeks of daily 50 mcg clen, its efficacy is reduced by ~40%ish on average - such that titrating the dose to 70 mcg for the same efficacy would be necessary for the average person. Are you the average person? Maybe. Maybe not. As Duchaine would say, you have to prove you're average.

I generally individualize its use if it is to be used at all. You might not be described by the mean, and not everybody has the same risk tolerance. For example, it's generally irrational to use clen if you're > 15% body fat and not deriving an income from your physique.

Nutrition is a more powerful lever than clen, doesn't risk fatal cardiovascular events - it actually reduces them, and doesn't cost money - it actually saves it.

My approach is proprietary and not something that I divulge on an internet forum.

I have written a comprehensive quasiarticle about clen here: Clenbuterol focus: Practical Research on Clen & Beta2- Adrenergic Compounds, Protocols
 
Never been a fan of clen. I’ve run it with t3 and still didn’t like it. I’ve done 2 weeks on/off, pyramid titrating, and using ketotifen to clear the receptors. Never did anything for me, to each their own
 
start 20mcg op 10 and max 40mcg of GOOD clen. PG Sopharma i feel i need 3-4 tabs 20mcg to feel the same as 1 40mcg Hilma tab. So It's not strange people 'need' +80-100mcg
 
It should be cycled because β2AR are subject to rapid tachyphylaxis (desensitization) because the receptor is a target for phosphorylation and because it binds β-arrestin, an accessory protein involved in G protein-coupled receptor desensitization.

To illustrate by way of example, β-arrestin -mediated G protein-coupled receptor interactions are also germane to heroin & morphine tolerance.

Doses have to increase to elicit the same results, and one should not use long-term.
Hi, I have come across this (and maybe you already have, as well):


What do you think about it?
 

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